Detail Information

Basic Information:


  VIRBase ID:  

HHID00099568

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           PANX2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p PANX2
miRBase
Accession/Entrez ID		 MIMAT0027574 56666
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - hPANX2//PX2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PANX2
chr22:50613900-50613901(+) m6A 3'UTR//intron       24981863
chr22:50613905-50613906(+) m6A 3'UTR//intron       25456834//24981863
chr22:50615371-50615372(+) m6A 3'UTR//CDS       25456834//24981863
chr22:50615763-50615764(+) m6A 3'UTR//CDS       24981863
chr22:50616021-50616022(+) m6A 3'UTR//CDS       -
chr22:50616045-50616046(+) m6A 3'UTR//CDS       -
chr22:50616201-50616202(+) m6A 3'UTR//CDS       24981863
chr22:50616234-50616235(+) m6A 3'UTR//CDS       24981863//22575960
chr22:50616350-50616351(+) m6A 3'UTR//CDS       22575960
chr22:50616357-50616358(+) m6A 3'UTR//CDS       22575960
chr22:50616501-50616502(+) m6A 3'UTR//CDS       24209618//25456834//24981863
chr22:50616549-50616550(+) m6A 3'UTR//CDS       24209618//25456834//24981863
chr22:50616573-50616574(+) m6A 3'UTR//CDS       24209618//25456834//24981863
chr22:50617620-50617621(+) m6A CDS//intron       24284625//24209618//25456834//24981863
chr22:50617776-50617777(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr22:50617881-50617882(+) m6A 3'UTR       24284625//25456834//24981863//22575960
chr22:50618068-50618069(+) m6A 3'UTR       -
chr22:50618193-50618194(+) m6A 3'UTR       24284625//24981863
chr22:50618217-50618218(+) m6A 3'UTR       24284625//24981863
chr22:50618275-50618276(+) m6A 3'UTR       24284625//24981863
chr22:50618293-50618294(+) m6A 3'UTR       24284625//24981863
chr22:50618306-50618307(+) m6A 3'UTR       24284625//24981863
chr22:50618329-50618330(+) m6A 3'UTR       24284625//24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
PANX2
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: PANX2

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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