Detail Information

Basic Information:


  VIRBase ID:  

HHID00099565

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           STEAP3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p STEAP3
miRBase
Accession/Entrez ID		 MIMAT0027574 55240
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AHMIO2//dudlin-2//dudulin-2//pHyde//STMP3//TSAP6

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR STEAP3
chr2:119994783(+) A-I      intronic
chr2:119994859(+) A-I      intronic
chr2:119994028(+) A-I      intronic
chr2:119997640(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED STEAP3
chr2:119985420(+) T-A intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase STEAP3
chr2:119981422-119981423(+) m6A 5'UTR       24981863
chr2:119988264-119988265(+) m6A 5'UTR//intron       24981863
chr2:119988441-119988442(+) m6A 5'UTR//intron       -
chr2:119988470-119988471(+) m6A 5'UTR//intron       -
chr2:119988483-119988484(+) m6A 5'UTR//intron       -
chr2:119988510-119988511(+) m6A 5'UTR//intron       -
chr2:119988571-119988572(+) m6A 5'UTR//intron       -
chr2:120003088-120003089(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr2:120003118-120003119(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr2:120003184-120003185(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr2:120003424-120003425(+) Cm CDS       -
chr2:120005648-120005649(+) m6A CDS       24284625
chr2:120015071-120015072(+) m6A CDS//intron       -
chr2:120015079-120015080(+) m6A CDS//intron       -
chr2:120015099-120015100(+) m6A CDS//intron       -
chr2:120015128-120015129(+) m6A CDS//intron       -
chr2:120020692-120020693(+) m6A 3'UTR//CDS       24284625
chr2:120020817-120020818(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr2:120020879-120020880(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr2:120020935-120020936(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr2:120021046-120021047(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr2:120021194-120021195(+) m6A 3'UTR       -
chr2:120021809-120021810(+) m6A 3'UTR       24981863//22608085
chr2:120021848-120021849(+) m6A 3'UTR       25456834//24981863//22608085
chr2:120021906-120021907(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr2:120021946-120021947(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085
chr2:120021970-120021971(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr2:120021979-120021980(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr2:120022025-120022026(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr2:120022059-120022060(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr2:120022187-120022188(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr2:120022224-120022225(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr2:120022261-120022262(+) m6A 3'UTR       25456834//24981863
chr2:120022570-120022571(+) m6A 3'UTR       -
chr2:120022910-120022911(+) m6A 3'UTR       24284625//25456834//24981863
chr2:120022928-120022929(+) m6A 3'UTR       24284625//25456834//24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
STEAP3
Chromatin K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: STEAP3

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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