Basic Information:

  VIRBase ID:  

HHID00099562

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:  MIMAT0027574          SUFU:  NM_016169     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-6836-5p	SUFU
miRBase Accession/Entrez ID	MIMAT0027574	51684
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	JBTS32//PRO1280//SUFUH//SUFUXL

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-6836-5p	rs1175923434 chr7:2257551    A/T rs1397797431 chr7:2257557    G/T rs1402374487 chr7:2257560    C/T rs373301992 chr7:2257555    C/T rs751019973 chr7:2257572    G/A rs751019973 chr7:2257572    G/T rs752401585 chr7:2257559    G/A rs752401585 chr7:2257559    G/C rs762697510 chr7:2257562    A/T rs765066033 chr7:2257558    C/A rs765066033 chr7:2257558    C/T rs767238780 chr7:2257563    G/A rs767238780 chr7:2257563    G/T rs776617786 chr7:2257553    G/A rs776617786 chr7:2257553    G/T rs1378787511 chr7:2257565    G/A rs747250755 chr7:2257571    C/CT rs756757197 chr7:2257570    G/A rs768462924 chr7:2257568    C/G rs780841384 chr7:2257571    C/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SUFU	chr10:104279803(+) A-I      intronic chr10:104365062(+) A-I      intronic chr10:104331397(+) A-I      intronic chr10:104331379(+) A-I      intronic chr10:104288098(+) A-I      intronic chr10:104331388(+) A-I      intronic chr10:104348233(+) A-I      intronic chr10:104328481(+) A-I      intronic chr10:104328479(+) A-I      intronic chr10:104334660(+) A-I      intronic chr10:104334692(+) A-I      intronic chr10:104334734(+) A-I      intronic chr10:104334910(+) A-I      intronic chr10:104335695(+) A-I      intronic chr10:104324113(+) A-I      intronic chr10:104335707(+) A-I      intronic chr10:104337623(+) A-I      intronic chr10:104345287(+) A-I      intronic chr10:104347307(+) A-I      intronic chr10:104288078(+) A-I      intronic chr10:104351182(+) A-I      intronic chr10:104358009(+) A-I      intronic chr10:104324176(+) A-I      intronic chr10:104364805(+) A-I      intronic chr10:104313257(+) A-I      intronic chr10:104312115(+) A-I      intronic chr10:104364954(+) A-I      intronic chr10:104288071(+) A-I      intronic chr10:104320316(+) A-I      intronic chr10:104312023(+) A-I      intronic chr10:104311992(+) A-I      intronic chr10:104365016(+) A-I      intronic chr10:104365017(+) A-I      intronic chr10:104284222(+) A-I      intronic chr10:104311744(+) A-I      intronic chr10:104317702(+) A-I      intronic chr10:104284255(+) A-I      intronic chr10:104324216(+) A-I      intronic chr10:104311734(+) A-I      intronic chr10:104317751(+) A-I      intronic chr10:104272661(+) A-I      intronic chr10:104317837(+) A-I      intronic chr10:104325431(+) A-I      intronic chr10:104311693(+) A-I      intronic chr10:104326497(+) A-I      intronic chr10:104326979(+) A-I      intronic chr10:104328359(+) A-I      intronic chr10:104287019(+) A-I      intronic chr10:104286966(+) A-I      intronic chr10:104286901(+) A-I      intronic chr10:104318042(+) A-I      intronic chr10:104313301(+) A-I      intronic chr10:104286877(+) A-I      intronic chr10:104330144(+) A-I      intronic chr10:104286859(+) A-I      intronic chr10:104330197(+) A-I      intronic chr10:104286189(+) A-I      intronic chr10:104295774(+) A-I      intronic chr10:104330200(+) A-I      intronic chr10:104317118(+) A-I      intronic chr10:104331412(+) A-I      intronic chr10:104331166(+) A-I      intronic chr10:104285119(+) A-I      intronic chr10:104332304(+) A-I      intronic chr10:104311681(+) A-I      intronic chr10:104311274(+) A-I      intronic chr10:104271535(+) A-I      intronic chr10:104322582(+) A-I      intronic chr10:104365010(+) A-I      intronic chr10:104316572(+) A-I      intronic chr10:104338342(+) A-I      intronic chr10:104300310(+) A-I      intronic chr10:104367831(+) A-I      intronic chr10:104322243(+) A-I      intronic chr10:104365022(+) A-I      intronic chr10:104285089(+) A-I      intronic chr10:104311667(+) A-I      intronic chr10:104363067(+) A-I      intronic chr10:104314033(+) A-I      intronic chr10:104285087(+) A-I      intronic chr10:104279668(+) A-I      intronic chr10:104336609(+) A-I      intronic chr10:104311248(+) A-I      intronic chr10:104279598(+) A-I      intronic chr10:104279177(+) A-I      intronic chr10:104322496(+) A-I      intronic chr10:104318236(+) A-I      intronic chr10:104279169(+) A-I      intronic chr10:104311244(+) A-I      intronic chr10:104325510(+) A-I      intronic chr10:104311242(+) A-I      intronic chr10:104279163(+) A-I      intronic chr10:104328392(+) A-I      intronic chr10:104279008(+) A-I      intronic chr10:104278751(+) A-I      intronic chr10:104285088(+) A-I      intronic chr10:104278440(+) A-I      intronic chr10:104311117(+) A-I      intronic chr10:104290383(+) A-I      intronic chr10:104310780(+) A-I      intronic chr10:104276925(+) A-I      intronic chr10:104312124(+) A-I      intronic chr10:104273797(+) A-I      intronic chr10:104317760(+) A-I      intronic chr10:104273783(+) A-I      intronic chr10:104270512(+) A-I      intronic chr10:104273743(+) A-I      intronic chr10:104322544(+) A-I      intronic chr10:104290733(+) A-I      intronic chr10:104272805(+) A-I      intronic chr10:104272663(+) A-I      intronic chr10:104270623(+) A-I      intronic chr10:104270622(+) A-I      intronic chr10:104326338(+) A-I      intronic chr10:104270501(+) A-I      intronic chr10:104316869(+) A-I      intronic chr10:104314039(+) A-I      intronic chr10:104314008(+) A-I      intronic chr10:104276329(+) A-I      intronic chr10:104278487(+) A-I      intronic chr10:104310735(+) A-I      intronic chr10:104331150(+) A-I      intronic chr10:104310684(+) A-I      intronic chr10:104316335(+) A-I      intronic chr10:104272760(+) A-I      intronic chr10:104367523(+) A-I      intronic chr10:104367830(+) A-I      intronic chr10:104322573(+) A-I      intronic chr10:104318094(+) A-I      intronic chr10:104366992(+) A-I      intronic chr10:104269700(+) A-I      intronic chr10:104326647(+) A-I      intronic chr10:104310660(+) A-I      intronic chr10:104313940(+) A-I      intronic chr10:104310616(+) A-I      intronic chr10:104290311(+) A-I      intronic chr10:104304377(+) A-I      intronic chr10:104326254(+) A-I      intronic chr10:104278562(+) A-I      intronic chr10:104304342(+) A-I      intronic chr10:104311970(+) A-I      intronic chr10:104304306(+) A-I      intronic chr10:104279629(+) A-I      intronic chr10:104320217(+) A-I      intronic chr10:104288117(+) A-I      intronic chr10:104336565(+) A-I      intronic chr10:104278470(+) A-I      intronic chr10:104313480(+) A-I      intronic chr10:104338452(+) A-I      intronic chr10:104320221(+) A-I      intronic chr10:104316421(+) A-I      intronic chr10:104304200(+) A-I      intronic chr10:104366900(+) A-I      intronic chr10:104302150(+) A-I      intronic chr10:104311383(+) A-I      intronic chr10:104288177(+) A-I      intronic chr10:104276805(+) A-I      intronic chr10:104318140(+) A-I      intronic chr10:104320625(+) A-I      intronic chr10:104290384(+) A-I      intronic chr10:104290739(+) A-I      intronic chr10:104286840(+) A-I      intronic chr10:104295919(+) A-I      intronic chr10:104295193(+) A-I      intronic chr10:104320273(+) A-I      intronic chr10:104314040(+) A-I      intronic chr10:104322118(+) A-I      intronic chr10:104322126(+) A-I      intronic chr10:104272683(+) A-I      intronic chr10:104290905(+) A-I      intronic chr10:104278804(+) A-I      intronic chr10:104322134(+) A-I      intronic chr10:104317786(+) A-I      intronic chr10:104322446(+) A-I      intronic chr10:104288306(+) A-I      intronic chr10:104322501(+) A-I      intronic chr10:104322527(+) A-I      intronic chr10:104313609(+) A-I      intronic chr10:104347963(+) A-I      intronic chr10:104322541(+) A-I      intronic chr10:104288181(+) A-I      intronic chr10:104317200(+) A-I      intronic chr10:104313604(+) A-I      intronic chr10:104288125(+) A-I      intronic chr10:104286899(+) A-I      intronic chr10:104272592(+) A-I      intronic chr10:104318067(+) A-I      intronic chr10:104316814(+) A-I      intronic chr10:104338344(+) A-I      intronic chr10:104311743(+) A-I      intronic chr10:104326975(+) A-I      intronic chr10:104311756(+) A-I      intronic chr10:104324219(+) A-I      intronic chr10:104330138(+) A-I      intronic chr10:104310592(+) A-I      intronic chr10:104311139(+) A-I      intronic chr10:104347899(+) A-I      intronic chr10:104324355(+) A-I      intronic chr10:104266404(+) A-I      intronic chr10:104311291(+) A-I      intronic chr10:104320319(+) A-I      intronic chr10:104323428(+) A-I      intronic chr10:104272588(+) A-I      intronic chr10:104286292(+) A-I      intronic chr10:104288242(+) A-I      intronic chr10:104295066(+) A-I      intronic chr10:104273882(+) A-I      intronic chr10:104320141(+) A-I      intronic chr10:104370030(+) A-I      intronic chr10:104301256(+) A-I      intronic chr10:104322212(+) A-I      intronic chr10:104324364(+) A-I      intronic chr10:104364789(+) A-I      intronic chr10:104337810(+) A-I      intronic chr10:104295795(+) A-I      intronic chr10:104279137(+) A-I      intronic chr10:104347378(+) A-I      intronic chr10:104279628(+) A-I      intronic chr10:104312024(+) A-I      intronic chr10:104313360(+) A-I      intronic chr10:104316380(+) A-I      intronic chr10:104326334(+) A-I      intronic chr10:104272776(+) A-I      intronic chr10:104322160(+) A-I      intronic chr10:104318211(+) A-I      intronic chr10:104364873(+) A-I      intronic chr10:104302572(+) A-I      intronic chr10:104331236(+) A-I      intronic chr10:104318068(+) A-I      intronic chr10:104285050(+) A-I      intronic chr10:104328450(+) A-I      intronic chr10:104295803(+) A-I      intronic chr10:104326553(+) A-I      intronic chr10:104271571(+) A-I      intronic chr10:104288145(+) A-I      intronic chr10:104318047(+) A-I      intronic chr10:104331221(+) A-I      intronic chr10:104326581(+) A-I      intronic chr10:104273906(+) A-I      intronic chr10:104278404(+) A-I      intronic chr10:104313973(+) A-I      intronic chr10:104283998(+) A-I      intronic chr10:104278469(+) A-I      intronic chr10:104312069(+) A-I      intronic chr10:104313325(+) A-I      intronic chr10:104320189(+) A-I      intronic chr10:104325419(+) A-I      intronic chr10:104265703(+) A-I      intronic chr10:104335619(+) A-I      intronic chr10:104314092(+) A-I      intronic chr10:104307345(+) A-I      intronic chr10:104316775(+) A-I      intronic chr10:104269708(+) A-I      intronic chr10:104337992(+) A-I      intronic chr10:104326344(+) A-I      intronic chr10:104269742(+) A-I      intronic chr10:104310599(+) A-I      intronic chr10:104271689(+) A-I      intronic chr10:104365121(+) A-I      intronic chr10:104317203(+) A-I      intronic chr10:104337809(+) A-I      intronic chr10:104276825(+) A-I      intronic chr10:104374535(+) A-I      intronic chr10:104278539(+) A-I      intronic chr10:104347898(+) A-I      intronic chr10:104314081(+) A-I      intronic chr10:104374625(+) A-I      intronic chr10:104271633(+) A-I      intronic chr10:104311973(+) A-I      intronic chr10:104331246(+) A-I      intronic chr10:104313472(+) A-I      intronic chr10:104286285(+) A-I      intronic chr10:104290932(+) A-I      intronic chr10:104288309(+) A-I      intronic chr10:104272740(+) A-I      intronic chr10:104326898(+) A-I      intronic chr10:104311275(+) A-I      intronic chr10:104285339(+) A-I      intronic chr10:104320651(+) A-I      intronic chr10:104317256(+) A-I      intronic chr10:104270757(+) A-I      intronic chr10:104288065(+) A-I      intronic chr10:104314072(+) A-I      intronic chr10:104295943(+) A-I      intronic chr10:104276870(+) A-I      intronic chr10:104276434(+) A-I      intronic chr10:104328455(+) A-I      intronic chr10:104291914(+) A-I      intronic chr10:104269643(+) A-I      intronic chr10:104290288(+) A-I      intronic chr10:104272769(+) A-I      intronic chr10:104271703(+) A-I      intronic chr10:104302119(+) A-I      intronic chr10:104285353(+) A-I      intronic chr10:104313494(+) A-I      intronic chr10:104364769(+) A-I      intronic chr10:104294995(+) A-I      intronic chr10:104367890(+) A-I      intronic chr10:104272679(+) A-I      intronic chr10:104318107(+) A-I      intronic chr10:104312067(+) A-I      intronic chr10:104291973(+) A-I      intronic chr10:104272668(+) A-I      intronic chr10:104314946(+) A-I      intronic chr10:104317365(+) A-I      intronic chr10:104331368(+) A-I      intronic chr10:104312049(+) A-I      intronic chr10:104288290(+) A-I      intronic chr10:104334891(+) A-I      intronic chr10:104297135(+) A-I      intronic chr10:104300343(+) A-I      intronic chr10:104330103(+) A-I      intronic chr10:104311344(+) A-I      intronic chr10:104336606(+) A-I      intronic chr10:104291961(+) A-I      intronic chr10:104270414(+) A-I      intronic chr10:104311230(+) A-I      intronic chr10:104345376(+) A-I      intronic chr10:104311611(+) A-I      intronic chr10:104326304(+) A-I      intronic chr10:104367407(+) A-I      intronic chr10:104272704(+) A-I      intronic chr10:104330171(+) A-I      intronic chr10:104311209(+) A-I      intronic chr10:104300521(+) A-I      intronic chr10:104367547(+) A-I      intronic chr10:104285529(+) A-I      intronic chr10:104330206(+) A-I      intronic chr10:104316701(+) A-I      intronic chr10:104311581(+) A-I      intronic chr10:104320072(+) A-I      intronic chr10:104322593(+) A-I      intronic chr10:104311621(+) A-I      intronic chr10:104316853(+) A-I      intronic chr10:104334904(+) A-I      intronic chr10:104332183(+) A-I      intronic chr10:104272614(+) A-I      intronic chr10:104382597(+) A-I      intronic chr10:104276951(+) A-I      intronic chr10:104278416(+) A-I      intronic chr10:104278550(+) A-I      intronic chr10:104270731(+) A-I      intronic chr10:104272564(+) A-I      intronic chr10:104310555(+) A-I      intronic chr10:104369879(+) A-I      intronic chr10:104313888(+) A-I      intronic chr10:104269741(+) A-I      intronic chr10:104326477(+) A-I      intronic chr10:104326369(+) A-I      intronic chr10:104286042(+) A-I      intronic chr10:104335865(+) A-I      intronic chr10:104322471(+) A-I      intronic chr10:104345475(+) A-I      intronic chr10:104272566(+) A-I      intronic chr10:104323343(+) A-I      intronic chr10:104305005(+) A-I      intronic chr10:104285425(+) A-I      intronic chr10:104348946(+) A-I      intronic chr10:104273754(+) A-I      intronic chr10:104272639(+) A-I      intronic chr10:104310761(+) A-I      intronic chr10:104327042(+) A-I      intronic chr10:104313595(+) A-I      intronic chr10:104340761(+) A-I      intronic chr10:104335751(+) A-I      intronic chr10:104310762(+) A-I      intronic chr10:104295851(+) A-I      intronic chr10:104312153(+) A-I      intronic chr10:104311689(+) A-I      intronic chr10:104317071(+) A-I      intronic chr10:104324207(+) A-I      intronic chr10:104331434(+) A-I      intronic chr10:104272655(+) A-I      intronic chr10:104326370(+) A-I      intronic chr10:104272770(+) A-I      intronic chr10:104276984(+) A-I      intronic chr10:104285047(+) A-I      intronic chr10:104294061(+) A-I      intronic chr10:104286055(+) A-I      intronic chr10:104278397(+) A-I      intronic chr10:104364818(+) A-I      intronic chr10:104270758(+) A-I      intronic chr10:104367823(+) A-I      intronic chr10:104366906(+) A-I      intronic chr10:104293257(+) A-I      intronic chr10:104266398(+) A-I      intronic chr10:104374055(+) A-I      intronic chr10:104312079(+) A-I      intronic chr10:104269850(+) A-I      intronic chr10:104320320(+) A-I      intronic chr10:104313427(+) A-I      intronic chr10:104314115(+) A-I      intronic chr10:104366923(+) A-I      intronic chr10:104272670(+) A-I      intronic chr10:104290280(+) A-I      intronic chr10:104300545(+) A-I      intronic chr10:104320065(+) A-I      intronic chr10:104367016(+) A-I      intronic chr10:104374534(+) A-I      intronic chr10:104312075(+) A-I      intronic chr10:104288185(+) A-I      intronic chr10:104331207(+) A-I      intronic chr10:104328478(+) A-I      intronic chr10:104316717(+) A-I      intronic chr10:104269618(+) A-I      intronic chr10:104312116(+) A-I      intronic chr10:104278818(+) A-I      intronic chr10:104326265(+) A-I      intronic chr10:104284036(+) A-I      intronic chr10:104270369(+) A-I      intronic chr10:104367901(+) A-I      intronic chr10:104318133(+) A-I      intronic chr10:104317080(+) A-I      intronic chr10:104316726(+) A-I      intronic chr10:104336608(+) A-I      intronic chr10:104318009(+) A-I      intronic chr10:104330180(+) A-I      intronic chr10:104367893(+) A-I      intronic chr10:104295904(+) A-I      intronic chr10:104337579(+) A-I      intronic chr10:104316838(+) A-I      intronic chr10:104327724(+) A-I      intronic chr10:104285835(+) A-I      intronic chr10:104326402(+) A-I      intronic chr10:104288207(+) A-I      intronic chr10:104318182(+) A-I      intronic chr10:104334271(+) A-I      intronic chr10:104285441(+) A-I      intronic chr10:104316725(+) A-I      intronic chr10:104284948(+) A-I      intronic chr10:104360376(+) A-I      intronic chr10:104322823(+) A-I      intronic chr10:104291735(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SUFU	chr10:104272704(+) A-I intron -    22327324 chr10:104272592(+) A-G intron -    22484847 chr10:104272704(+) A-G intron -    22484847 chr10:104272769(+) A-G intron -    22484847 chr10:104272770(+) A-G intron -    22484847 chr10:104286292(+) A-G intron -    22484847 chr10:104311973(+) A-G intron -    22484847 chr10:104312153(+) A-G intron -    22484847 chr10:104330171(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SUFU	chr10:104263757-104263758(+) m6A 5'UTR       24981863 chr10:104263787-104263788(+) m6A 5'UTR       24981863 chr10:104264007-104264008(+) m6A CDS       24209618 chr10:104351310-104351311(+) Y intron       16381836 chr10:104351319-104351320(+) Y intron       16381836 chr10:104389827-104389828(+) m6A CDS       24284625//22608085 chr10:104390010-104390011(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:104390025-104390026(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:104390164-104390165(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:104390215-104390216(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:104390240-104390241(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:104390294-104390295(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:104390375-104390376(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr10:104390428-104390429(+) m6A 3'UTR       24284625//24981863 chr10:104390490-104390491(+) m6A 3'UTR       24981863 chr10:104390495-104390496(+) m6A 3'UTR       24981863 chr10:104390512-104390513(+) m6A 3'UTR       24981863 chr10:104391229-104391230(+) m6A 3'UTR       24284625 chr10:104391277-104391278(+) m6A 3'UTR       24284625 chr10:104391420-104391421(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr10:104391504-104391505(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr10:104391615-104391616(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr10:104391658-104391659(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:104391695-104391696(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:104391834-104391835(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr10:104391851-104391852(+) m6A 3'UTR       24284625//25456834//24981863 chr10:104391993-104391994(+) m6A 3'UTR       24284625//25456834//24981863 chr10:104392012-104392013(+) m6A 3'UTR       24284625//25456834//24981863 chr10:104392023-104392024(+) m6A 3'UTR       24284625//25456834//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-6836-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	SUFU	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-6836-5p
Interactor2: SUFU

Evidence Support:

Weak-Evidence	Illumina sequencing
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32223537	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Calu-3 cells	Interactor2 expression	Downregulation
Description	The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.