Basic Information:

  VIRBase ID:  

HHID00099558

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:  MIMAT0027574          CNNM4:  NM_020184     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-6836-5p	CNNM4
miRBase Accession/Entrez ID	MIMAT0027574	26504
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ACDP4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-6836-5p	rs1175923434 chr7:2257551    A/T rs1397797431 chr7:2257557    G/T rs1402374487 chr7:2257560    C/T rs373301992 chr7:2257555    C/T rs751019973 chr7:2257572    G/A rs751019973 chr7:2257572    G/T rs752401585 chr7:2257559    G/A rs752401585 chr7:2257559    G/C rs762697510 chr7:2257562    A/T rs765066033 chr7:2257558    C/A rs765066033 chr7:2257558    C/T rs767238780 chr7:2257563    G/A rs767238780 chr7:2257563    G/T rs776617786 chr7:2257553    G/A rs776617786 chr7:2257553    G/T rs1378787511 chr7:2257565    G/A rs747250755 chr7:2257571    C/CT rs756757197 chr7:2257570    G/A rs768462924 chr7:2257568    C/G rs780841384 chr7:2257571    C/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CNNM4	chr2:97443662(+) A-I      intronic chr2:97473730(+) A-I      intronic chr2:97470438(+) A-I      intronic chr2:97473378(+) A-I      intronic chr2:97473792(+) A-I      intronic chr2:97470462(+) A-I      intronic chr2:97470439(+) A-I      intronic chr2:97470440(+) A-I      intronic chr2:97470447(+) A-I      intronic chr2:97470459(+) A-I      intronic chr2:97473755(+) A-I      intronic chr2:97448038(+) A-I      intronic chr2:97451283(+) A-I      intronic chr2:97451407(+) A-I      intronic chr2:97451420(+) A-I      intronic chr2:97450715(+) A-I      intronic chr2:97453493(+) A-I      intronic chr2:97453718(+) A-I      intronic chr2:97453745(+) A-I      intronic chr2:97453777(+) A-I      intronic chr2:97455530(+) A-I      intronic chr2:97455556(+) A-I      intronic chr2:97455869(+) A-I      intronic chr2:97461982(+) A-I      intronic chr2:97469212(+) A-I      intronic chr2:97469286(+) A-I      intronic chr2:97469305(+) A-I      intronic chr2:97469332(+) A-I      intronic chr2:97469342(+) A-I      intronic chr2:97469343(+) A-I      intronic chr2:97469388(+) A-I      intronic chr2:97469675(+) A-I      intronic chr2:97469753(+) A-I      intronic chr2:97469765(+) A-I      intronic chr2:97470647(+) A-I      intronic chr2:97469860(+) A-I      intronic chr2:97470256(+) A-I      intronic chr2:97470661(+) A-I      intronic chr2:97472828(+) A-I      intronic chr2:97472841(+) A-I      intronic chr2:97472847(+) A-I      intronic chr2:97472865(+) A-I      intronic chr2:97472873(+) A-I      intronic chr2:97472887(+) A-I      intronic chr2:97473182(+) A-I      intronic chr2:97473352(+) A-I      intronic chr2:97473365(+) A-I      intronic chr2:97473392(+) A-I      intronic chr2:97473393(+) A-I      intronic chr2:97473649(+) A-I      intronic chr2:97473651(+) A-I      intronic chr2:97473670(+) A-I      intronic chr2:97473712(+) A-I      intronic chr2:97473751(+) A-I      intronic chr2:97473811(+) A-I      intronic chr2:97430470(+) A-I      intronic chr2:97430537(+) A-I      intronic chr2:97430545(+) A-I      intronic chr2:97430546(+) A-I      intronic chr2:97430547(+) A-I      intronic chr2:97433645(+) A-I      intronic chr2:97433787(+) A-I      intronic chr2:97437187(+) A-I      intronic chr2:97440530(+) A-I      intronic chr2:97442453(+) A-I      intronic chr2:97442489(+) A-I      intronic chr2:97453467(+) A-I      intronic chr2:97442498(+) A-I      intronic chr2:97442515(+) A-I      intronic chr2:97443312(+) A-I      intronic chr2:97445040(+) A-I      intronic chr2:97445178(+) A-I      intronic chr2:97447055(+) A-I      intronic chr2:97447110(+) A-I      intronic chr2:97451677(+) A-I      intronic chr2:97447135(+) A-I      intronic chr2:97447142(+) A-I      intronic chr2:97447148(+) A-I      intronic chr2:97447212(+) A-I      intronic chr2:97447214(+) A-I      intronic chr2:97447220(+) A-I      intronic chr2:97447900(+) A-I      intronic chr2:97473174(+) A-I      intronic chr2:97472812(+) A-I      intronic chr2:97473131(+) A-I      intronic chr2:97443371(+) A-I      intronic chr2:97473357(+) A-I      intronic chr2:97451605(+) A-I      intronic chr2:97469715(+) A-I      intronic chr2:97462062(+) A-I      intronic chr2:97473460(+) A-I      intronic chr2:97444214(+) A-I      intronic chr2:97469206(+) A-I      intronic chr2:97470475(+) A-I      intronic chr2:97473765(+) A-I      intronic chr2:97451475(+) A-I      intronic chr2:97473178(+) A-I      intronic chr2:97470684(+) A-I      intronic chr2:97473007(+) A-I      intronic chr2:97470232(+) A-I      intronic chr2:97455699(+) A-I      intronic chr2:97473183(+) A-I      intronic chr2:97473791(+) A-I      intronic chr2:97472825(+) A-I      intronic chr2:97462043(+) A-I      intronic chr2:97449924(+) A-I      intronic chr2:97473184(+) A-I      intronic chr2:97431995(+) A-I      intronic chr2:97473840(+) A-I      intronic chr2:97456545(+) A-I      intronic chr2:97472981(+) A-I      intronic chr2:97469287(+) A-I      intronic chr2:97440618(+) A-I      intronic chr2:97456542(+) A-I      intronic chr2:97469261(+) A-I      intronic chr2:97469775(+) A-I      intronic chr2:97470535(+) A-I      intronic chr2:97470695(+) A-I      intronic chr2:97450812(+) A-I      intronic chr2:97430469(+) A-I      intronic chr2:97473725(+) A-I      intronic chr2:97462039(+) A-I      intronic chr2:97462011(+) A-I      intronic chr2:97451498(+) A-I      intronic chr2:97469762(+) A-I      intronic chr2:97462159(+) A-I      intronic chr2:97444835(+) A-I      intronic chr2:97443657(+) A-I      intronic chr2:97470639(+) A-I      intronic chr2:97431046(+) A-I      intronic chr2:97462418(+) A-I      intronic chr2:97439433(+) A-I      intronic chr2:97470512(+) A-I      intronic chr2:97469316(+) A-I      intronic chr2:97473719(+) A-I      intronic chr2:97469748(+) A-I      intronic chr2:97469266(+) A-I      intronic chr2:97469279(+) A-I      intronic chr2:97473454(+) A-I      intronic chr2:97469736(+) A-I      intronic chr2:97469408(+) A-I      intronic chr2:97473198(+) A-I      intronic chr2:97469298(+) A-I      intronic chr2:97445230(+) A-I      intronic chr2:97445640(+) A-I      intronic chr2:97473899(+) A-I      intronic chr2:97473700(+) A-I      intronic chr2:97473806(+) A-I      intronic chr2:97455424(+) A-I      intronic chr2:97453451(+) A-I      intronic chr2:97453413(+) A-I      intronic chr2:97453474(+) A-I      intronic chr2:97470278(+) A-I      intronic chr2:97447077(+) A-I      intronic chr2:97473201(+) A-I      intronic chr2:97469207(+) A-I      intronic chr2:97456462(+) A-I      intronic chr2:97451118(+) A-I      intronic chr2:97472931(+) A-I      intronic chr2:97470412(+) A-I      intronic chr2:97447213(+) A-I      intronic chr2:97473901(+) A-I      intronic chr2:97473351(+) A-I      intronic chr2:97469223(+) A-I      intronic chr2:97470067(+) A-I      intronic chr2:97431992(+) A-I      intronic chr2:97473423(+) A-I      intronic chr2:97470712(+) A-I      intronic chr2:97473823(+) A-I      intronic chr2:97472984(+) A-I      intronic chr2:97469700(+) A-I      intronic chr2:97470323(+) A-I      intronic chr2:97456535(+) A-I      intronic chr2:97431938(+) A-I      intronic chr2:97456543(+) A-I      intronic chr2:97445233(+) A-I      intronic chr2:97469710(+) A-I      intronic chr2:97472860(+) A-I      intronic chr2:97445090(+) A-I      intronic chr2:97447922(+) A-I      intronic chr2:97469722(+) A-I      intronic chr2:97473826(+) A-I      intronic chr2:97473800(+) A-I      intronic chr2:97469840(+) A-I      intronic chr2:97455697(+) A-I      intronic chr2:97453461(+) A-I      intronic chr2:97431003(+) A-I      intronic chr2:97451293(+) A-I      intronic chr2:97473391(+) A-I      intronic chr2:97431951(+) A-I      intronic chr2:97470195(+) A-I      intronic chr2:97469703(+) A-I      intronic chr2:97445714(+) A-I      intronic chr2:97455429(+) A-I      intronic chr2:97473809(+) A-I      intronic chr2:97431905(+) A-I      intronic chr2:97448002(+) A-I      intronic chr2:97445181(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CNNM4	chr2:97462011(+) A-I intron -    22028664 chr2:97462039(+) A-I intron -    22028664 chr2:97462043(+) A-I intron -    22028664 chr2:97462062(+) A-I intron -    22028664 chr2:97462121(+) A-I intron -    22028664 chr2:97462159(+) A-I intron -    22028664 chr2:97469762(+) A-I intron -    21960545 chr2:97469775(+) A-I intron -    21960545 chr2:97473700(+) A-I intron -    21960545 chr2:97473826(+) A-I intron -    21960545 chr2:97431905(+) A-G intron -    22484847 chr2:97441521(+) A-G intron -    22484847 chr2:97442467(+) A-G intron -    22484847 chr2:97442479(+) A-G intron -    22484847 chr2:97443371(+) A-G intron -    22484847 chr2:97444835(+) A-G intron -    22484847 chr2:97445090(+) A-G intron -    22484847 chr2:97445640(+) A-G intron -    22484847 chr2:97448028(+) A-G intron -    22484847 chr2:97450812(+) A-G intron -    22484847 chr2:97451605(+) A-G intron -    22484847 chr2:97453413(+) A-G intron -    22484847 chr2:97453737(+) A-G intron -    22484847 chr2:97462043(+) A-G intron -    22484847 chr2:97462121(+) A-G intron -    22484847 chr2:97469206(+) A-G intron -    22484847 chr2:97469207(+) A-G intron -    22484847 chr2:97469223(+) A-G intron -    22484847 chr2:97469266(+) A-G intron -    22484847 chr2:97469279(+) A-G intron -    22484847 chr2:97469287(+) A-G intron -    22484847 chr2:97469298(+) A-G intron -    22484847 chr2:97469301(+) A-G intron -    22484847 chr2:97469316(+) A-G intron -    22484847 chr2:97469710(+) A-G intron -    22484847 chr2:97470195(+) A-G intron -    22484847 chr2:97470232(+) A-G intron -    22484847 chr2:97470278(+) A-G intron -    22484847 chr2:97470710(+) A-G intron -    22484847 chr2:97473351(+) A-G intron -    22484847 chr2:97473357(+) A-G intron -    22484847 chr2:97473700(+) A-G intron -    22484847 chr2:97473719(+) A-G intron -    22484847 chr2:97473725(+) A-G intron -    22484847 chr2:97473726(+) A-G intron -    22484847 chr2:97473752(+) A-G intron -    22484847 chr2:97473765(+) A-G intron -    22484847 chr2:97473791(+) A-G intron -    22484847 chr2:97473809(+) A-G intron -    22484847 chr2:97473826(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CNNM4	chr2:97426774-97426775(+) m6A CDS       24209618 chr2:97426917-97426918(+) m6A CDS       - chr2:97426959-97426960(+) m6A CDS       24284625 chr2:97427036-97427037(+) m6A CDS       24284625 chr2:97427076-97427077(+) m6A CDS       24284625//22608085 chr2:97427115-97427116(+) m6A CDS       24284625//25456834//24981863//22608085 chr2:97427229-97427230(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr2:97427235-97427236(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr2:97427364-97427365(+) m6A CDS       24284625//24209618//24981863//22608085 chr2:97427391-97427392(+) m6A CDS       24284625//24209618//22608085 chr2:97427520-97427521(+) m6A CDS       24284625//22608085 chr2:97427709-97427710(+) m6A CDS       24284625//24209618//24981863//22608085 chr2:97427836-97427837(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr2:97427843-97427844(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr2:97427849-97427850(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr2:97427880-97427881(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr2:97427913-97427914(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr2:97428012-97428013(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr2:97428027-97428028(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr2:97428053-97428054(+) m6A CDS       24284625//24981863//22575960//22608085 chr2:97463285-97463286(+) m6A CDS//exon       24284625 chr2:97463318-97463319(+) m6A CDS//exon       24284625 chr2:97464872-97464873(+) m6A CDS//exon       - chr2:97465319-97465320(+) m6A CDS//exon       - chr2:97465357-97465358(+) m6A CDS//exon       - chr2:97475368-97475369(+) m6A 3'UTR       24981863 chr2:97475415-97475416(+) m6A 3'UTR       24981863 chr2:97475562-97475563(+) m6A 3'UTR       24981863//22608085 chr2:97475575-97475576(+) m6A 3'UTR       24981863//22608085 chr2:97475610-97475611(+) m6A 3'UTR       24981863//22608085 chr2:97475651-97475652(+) m6A 3'UTR       24981863//22608085 chr2:97475784-97475785(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr2:97475807-97475808(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr2:97475901-97475902(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr2:97475966-97475967(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr2:97475998-97475999(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr2:97476010-97476011(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr2:97476046-97476047(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr2:97476320-97476321(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-6836-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	CNNM4	Chromatin K562 cells     - Exosome Blood     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-6836-5p
Interactor2: CNNM4

Evidence Support:

Weak-Evidence	Illumina sequencing
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32223537	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Calu-3 cells	Interactor2 expression	Downregulation
Description	The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.