Detail Information

Basic Information:


  VIRBase ID:  

HHID00099497

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6807-5p:           FKBP14:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6807-5p FKBP14
miRBase
Accession/Entrez ID		 MIMAT0027514 55033
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - EDSKMH//EDSKSCL2//FKBP22//IPBP12

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6807-5p
rs1244387925 chr19:58550301    G/A
rs1313867143 chr19:58550296    G/C
rs1385520114 chr19:58550300    G/A
rs1391124651 chr19:58550293    G/A
rs757408357 chr19:58550306    G/A
rs906745936 chr19:58550297    A/G
rs919459806 chr19:58550295    G/A
rs751886149 chr19:58550292    A/G
rs992293809 chr19:58550287    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR FKBP14
chr7:30054951(-) A-I      intronic
chr7:30054952(-) A-I      intronic
chr7:30057019(-) A-I      intronic
chr7:30054987(-) A-I      intronic
chr7:30054993(-) A-I      intronic
chr7:30063032(-) A-I      intronic
chr7:30057133(-) A-I      intronic
chr7:30057444(-) A-I      intronic
chr7:30055020(-) A-I      intronic
chr7:30057045(-) A-I      intronic
chr7:30056943(-) A-I      intronic
chr7:30056930(-) A-I      intronic
chr7:30054958(-) A-I      intronic
chr7:30055028(-) A-I      intronic
chr7:30050830(-) A-I      3'UTR
chr7:30050834(-) A-I      3'UTR
chr7:30051271(-) A-I      3'UTR
chr7:30050860(-) A-I      3'UTR
chr7:30050858(-) A-I      3'UTR
chr7:30050832(-) A-I      3'UTR
chr7:30050839(-) A-I      3'UTR
chr7:30050789(-) A-I      3'UTR
chr7:30050836(-) A-I      3'UTR
chr7:30050845(-) A-I      3'UTR
chr7:30050861(-) A-I      3'UTR
chr7:30051295(-) A-I      3'UTR
chr7:30051322(-) A-I      3'UTR
chr7:30050835(-) A-I      3'UTR
chr7:30050852(-) A-I      3'UTR
chr7:30057224(-) A-I      intronic
chr7:30057461(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase FKBP14
chr7:30050313-30050314(-) m6A 3'UTR       27773535
chr7:30053450-30053451(-) m6A 3'UTR       24981863//27773535
chr7:30053464-30053465(-) m6A 3'UTR       24981863//27773535
chr7:30053500-30053501(-) m6A 3'UTR       24981863//27773535//22608085
chr7:30053528-30053529(-) m6A 3'UTR       24981863//27773535//22608085
chr7:30053574-30053575(-) m6A 3'UTR       24981863//27773535//22608085
chr7:30053671-30053672(-) m6A 3'UTR       24981863
chr7:30053694-30053695(-) m6A 3'UTR       24981863
chr7:30053788-30053789(-) m6A 3'UTR       24981863//22608085
chr7:30053846-30053847(-) m6A 3'UTR       24981863//22608085
chr7:30053868-30053869(-) m6A 3'UTR       24981863//22608085
chr7:30054124-30054125(-) m6A 3'UTR       24981863//22608085
chr7:30054132-30054133(-) m6A 3'UTR       24981863//22608085
chr7:30054210-30054211(-) m6A 3'UTR       24981863//22608085
chr7:30054365-30054366(-) m6A 3'UTR//CDS       24981863//27773535
chr7:30054405-30054406(-) m6A 3'UTR//CDS       24981863//27773535
chr7:30054476-30054477(-) m6A 3'UTR//CDS       24981863//27773535
chr7:30058626-30058627(-) m6A 3'UTR//CDS       24981863//27773535
chr7:30058677-30058678(-) m6A 3'UTR//CDS       27773535
chr7:30066000-30066001(-) m6A CDS//exon       24284625
chr7:30066052-30066053(-) m6A CDS//exon       24284625
chr7:30066146-30066147(-) m6A 5'UTR//exon       24284625//24981863//22608085
chr7:30066168-30066169(-) m6A 5'UTR//exon       24284625//24981863//22608085
chr7:30066198-30066199(-) m6A 5'UTR//exon       24284625//24981863//22608085
chr7:30066230-30066231(-) m6A 5'UTR//exon       24284625//24981863//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6807-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
FKBP14
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6807-5p
Interactor2: FKBP14

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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