Detail Information

Basic Information:


  VIRBase ID:  

HHID00099433

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-619-5p:           LSM11:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-619-5p LSM11
miRBase
Accession/Entrez ID		 MIMAT0026622 134353
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-619-5p
rs1173633685 chr12:108836970    C/A
rs1360600602 chr12:108836973    G/A
rs368283564 chr12:108836983    C/A
rs747519669 chr12:108836968    T/A
rs747519669 chr12:108836968    T/G
rs1395416108 chr12:108836979    C/G
rs1466244611 chr12:108836977    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR LSM11
chr5:157178052(+) A-I      intronic
chr5:157181609(+) A-I      intronic
chr5:157173716(+) A-I      intronic
chr5:157177931(+) A-I      intronic
chr5:157178010(+) A-I      intronic
chr5:157178042(+) A-I      intronic
chr5:157184023(+) A-I      3'UTR
chr5:157183990(+) A-I      3'UTR
chr5:157185366(+) A-I      3'UTR
chr5:157184123(+) A-I      3'UTR
chr5:157184086(+) A-I      3'UTR
chr5:157184016(+) A-I      3'UTR
chr5:157185357(+) A-I      3'UTR
chr5:157183964(+) A-I      3'UTR
chr5:157183956(+) A-I      3'UTR
chr5:157184131(+) A-I      3'UTR
chr5:157185343(+) A-I      3'UTR
chr5:157184180(+) A-I      3'UTR
chr5:157184013(+) A-I      3'UTR
chr5:157184009(+) A-I      3'UTR
chr5:157185375(+) A-I      3'UTR
chr5:157173797(+) A-I      intronic
chr5:157183921(+) A-I      3'UTR
chr5:157185311(+) A-I      3'UTR
chr5:157185294(+) A-I      3'UTR
chr5:157184012(+) A-I      3'UTR
chr5:157183959(+) A-I      3'UTR
chr5:157185216(+) A-I      3'UTR
chr5:157184014(+) A-I      3'UTR
chr5:157184059(+) A-I      3'UTR
chr5:157185302(+) A-I      3'UTR
chr5:157184095(+) A-I      3'UTR
chr5:157185151(+) A-I      3'UTR
chr5:157185319(+) A-I      3'UTR
chr5:157185261(+) A-I      3'UTR
chr5:157185323(+) A-I      3'UTR
chr5:157183920(+) A-I      3'UTR
chr5:157183988(+) A-I      3'UTR
chr5:157184063(+) A-I      3'UTR
chr5:157185223(+) A-I      3'UTR
chr5:157185376(+) A-I      3'UTR
chr5:157185192(+) A-I      3'UTR
chr5:157185336(+) A-I      3'UTR
chr5:157185388(+) A-I      3'UTR
chr5:157184080(+) A-I      3'UTR
chr5:157185252(+) A-I      3'UTR
chr5:157183912(+) A-I      3'UTR
chr5:157185227(+) A-I      3'UTR
chr5:157173830(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LSM11
chr5:157181954-157181955(+) m6A CDS       24284625//22608085
chr5:157181994-157181995(+) m6A CDS       24284625//25456834//24981863//22608085
chr5:157182089-157182090(+) m6A CDS       24284625//25456834//24981863//22608085
chr5:157182098-157182099(+) m6A CDS       24284625//25456834//24981863//22608085
chr5:157182437-157182438(+) m6A 3'UTR       24981863
chr5:157183239-157183240(+) m6A 3'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-619-5p
Exosome Pooled sera     27278097
Exosome Serum     24683445
Exosome Kidney tissue     -
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
LSM11
Exosome Blood     -
Nucleoplasm K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-619-5p
Interactor2: LSM11

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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