Basic Information:

  VIRBase ID:  

HHID00099202

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-2392:  MIMAT0019043          ITGA11:  NM_001004439     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-2392	ITGA11
miRBase Accession/Entrez ID	MIMAT0019043	22801
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	HsT18964

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-2392	rs1193524402 chr14:100814551    T/C rs1402511503 chr14:100814570    G/A rs761601922 chr14:100814567    G/A rs761601922 chr14:100814567    G/C rs118055959 chr14:100814555    A/G rs1235148713 chr14:100814554    G/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ITGA11	chr15:68709133(-) A-I      intronic chr15:68709129(-) A-I      intronic chr15:68709120(-) A-I      intronic chr15:68709160(-) A-I      intronic chr15:68602043(-) A-I      intronic chr15:68602018(-) A-I      intronic chr15:68651875(-) A-I      intronic chr15:68644637(-) A-I      intronic chr15:68600188(-) A-I      intronic chr15:68644659(-) A-I      intronic chr15:68598360(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ITGA11	chr15:68594201-68594202(-) m6A 3'UTR       24981863 chr15:68594234-68594235(-) m6A 3'UTR       24981863 chr15:68594289-68594290(-) m6A 3'UTR       24981863 chr15:68594533-68594534(-) m6A 3'UTR       24981863 chr15:68594761-68594762(-) m6A 3'UTR       24981863 chr15:68594782-68594783(-) m6A 3'UTR       24981863 chr15:68594798-68594799(-) m6A 3'UTR       24981863 chr15:68594850-68594851(-) m6A 3'UTR       24981863 chr15:68594960-68594961(-) m6A 3'UTR       24981863 chr15:68594965-68594966(-) m6A 3'UTR       24981863 chr15:68595010-68595011(-) m6A 3'UTR       24981863 chr15:68595023-68595024(-) m6A 3'UTR       24981863 chr15:68595037-68595038(-) m6A 3'UTR       24981863 chr15:68595154-68595155(-) m6A 3'UTR       24981863 chr15:68595174-68595175(-) m6A 3'UTR       24981863 chr15:68595189-68595190(-) m6A 3'UTR       24981863 chr15:68595195-68595196(-) m6A 3'UTR       24981863 chr15:68595211-68595212(-) m6A 3'UTR       24981863 chr15:68595233-68595234(-) m6A 3'UTR       24981863 chr15:68595336-68595337(-) m6A 3'UTR       24981863 chr15:68595359-68595360(-) m6A 3'UTR       24981863 chr15:68595382-68595383(-) m6A 3'UTR       24981863 chr15:68595421-68595422(-) m6A CDS       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-2392	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	ITGA11	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-2392
Interactor2: ITGA11

Evidence Support:

Weak-Evidence	Illumina sequencing
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32223537	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Calu-3 cells	Interactor2 expression	Upregulation
Description	The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.