Detail Information

Basic Information:


  VIRBase ID:  

HHID00099135

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-762:           CYB561A3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-762 CYB561A3
miRBase
Accession/Entrez ID		 MIMAT0010313 220002
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CYBASC3//LCYTB

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-762
rs1379218716 chr16:30893951    G/A
rs1401867087 chr16:30893964    G/A
rs1406702631 chr16:30893966    G/A
rs1407433182 chr16:30893961    C/G
rs374396561 chr16:30893962    C/T
rs751832217 chr16:30893968    C/G
rs752364708 chr16:30893961    CCGGGGCCGAGCCCGCGG/C
rs755205907 chr16:30893971    G/T
rs758841312 chr16:30893963    G/A
rs758841312 chr16:30893963    G/C
rs1241251631 chr16:30893956    T/A
rs1288563923 chr16:30893956    T/TGGGGCC
rs1307177311 chr16:30893953    G/A
rs750763225 chr16:30893954    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CYB561A3
chr11:61119746(-) A-I      3'UTR
chr11:61119476(-) A-I      3'UTR
chr11:61120050(-) A-I      3'UTR
chr11:61123488(-) A-I      intronic
chr11:61122031(-) A-I      intronic
chr11:61123388(-) A-I      intronic
chr11:61125624(-) A-I      intronic
chr11:61123403(-) A-I      intronic
chr11:61123477(-) A-I      intronic
chr11:61123397(-) A-I      intronic
chr11:61123495(-) A-I      intronic
chr11:61123442(-) A-I      intronic
chr11:61123452(-) A-I      intronic
chr11:61123380(-) A-I      intronic
chr11:61119034(-) A-I      3'UTR
chr11:61119143(-) A-I      3'UTR
chr11:61119191(-) A-I      3'UTR
chr11:61120089(-) A-I      3'UTR
chr11:61119257(-) A-I      3'UTR
chr11:61119253(-) A-I      3'UTR
chr11:61119241(-) A-I      3'UTR
chr11:61119230(-) A-I      3'UTR
chr11:61118910(-) A-I      3'UTR
chr11:61118900(-) A-I      3'UTR
chr11:61119277(-) A-I      3'UTR
chr11:61118867(-) A-I      3'UTR
chr11:61119334(-) A-I      3'UTR
chr11:61120119(-) A-I      3'UTR
chr11:61119372(-) A-I      3'UTR
chr11:61119347(-) A-I      3'UTR
chr11:61118873(-) A-I      3'UTR
chr11:61120107(-) A-I      3'UTR
chr11:61118890(-) A-I      3'UTR
chr11:61119377(-) A-I      3'UTR
chr11:61120008(-) A-I      3'UTR
chr11:61120021(-) A-I      3'UTR
chr11:61118929(-) A-I      3'UTR
chr11:61118930(-) A-I      3'UTR
chr11:61120064(-) A-I      3'UTR
chr11:61122030(-) A-I      intronic
chr11:61123305(-) A-I      intronic
chr11:61122541(-) A-I      intronic
chr11:61122376(-) A-I      intronic
chr11:61122512(-) A-I      intronic
chr11:61121923(-) A-I      intronic
chr11:61123538(-) A-I      intronic
chr11:61125632(-) A-I      intronic
chr11:61122446(-) A-I      intronic
chr11:61122082(-) A-I      intronic
chr11:61122018(-) A-I      intronic
chr11:61122406(-) A-I      intronic
chr11:61125671(-) A-I      intronic
chr11:61122635(-) A-I      intronic
chr11:61122005(-) A-I      intronic
chr11:61122612(-) A-I      intronic
chr11:61121869(-) A-I      intronic
chr11:61122373(-) A-I      intronic
chr11:61123372(-) A-I      intronic
chr11:61119575(-) A-I      3'UTR
chr11:61119571(-) A-I      3'UTR
chr11:61119263(-) A-I      3'UTR
chr11:61120087(-) A-I      3'UTR
chr11:61120011(-) A-I      3'UTR
chr11:61119131(-) A-I      3'UTR
chr11:61119751(-) A-I      3'UTR
chr11:61119128(-) A-I      3'UTR
chr11:61119269(-) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CYB561A3
chr11:61116565-61116566(-) m6A 3'UTR//exon       25456834//27773535
chr11:61116764-61116765(-) m6A 3'UTR//exon       27773535
chr11:61116958-61116959(-) m6A 3'UTR//exon       25456834//24981863
chr11:61117012-61117013(-) m6A 3'UTR//exon       25456834//24981863
chr11:61120545-61120546(-) m6A 3'UTR//CDS//exon//intron       25456834//27773535
chr11:61120853-61120854(-) m6A exon//intron       24981863
chr11:61120860-61120861(-) m6A exon//intron       24981863
chr11:61120870-61120871(-) m6A exon//intron       24981863
chr11:61124082-61124083(-) Y CDS//exon//intron       26075521
chr11:61129432-61129433(-) m6A 5'UTR//exon//intron       24284625//25456834//24981863//27371828//27773536
chr11:61129517-61129518(-) m6A 5'UTR//exon       24284625//25456834//24981863//27371828//27773536//22608085
chr11:61129530-61129531(-) m6A 5'UTR//exon       25456834//24981863//27371828//27773536//22608085
chr11:61129592-61129593(-) m6A 5'UTR//exon       24284625//25456834//24981863//27773536//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-762
Exosome Pooled sera     27278097
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Hepatoma cells     23771658
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
CYB561A3
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-762
Gemcitabine 60750 Drug interaction    RC00007981
Imatinib 5291 Drug interaction    RC00007980
Bortezomib 387447 Drug interaction    RC00007983
5-Fluorouracil 3385 Drug interaction    RC00007979
Gefitinib 123631 Drug interaction    RC00007982
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-762
Crizotinib       11626560

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-762
Interactor2: CYB561A3

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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