Detail Information

Basic Information:


  VIRBase ID:  

HHID00099110

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-762:           MARVELD1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-762 MARVELD1
miRBase
Accession/Entrez ID		 MIMAT0010313 83742
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - bA548K23.8//GB14//MARVD1//MRVLDC1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-762
rs1379218716 chr16:30893951    G/A
rs1401867087 chr16:30893964    G/A
rs1406702631 chr16:30893966    G/A
rs1407433182 chr16:30893961    C/G
rs374396561 chr16:30893962    C/T
rs751832217 chr16:30893968    C/G
rs752364708 chr16:30893961    CCGGGGCCGAGCCCGCGG/C
rs755205907 chr16:30893971    G/T
rs758841312 chr16:30893963    G/A
rs758841312 chr16:30893963    G/C
rs1241251631 chr16:30893956    T/A
rs1288563923 chr16:30893956    T/TGGGGCC
rs1307177311 chr16:30893953    G/A
rs750763225 chr16:30893954    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MARVELD1
chr10:99480338(+) A-I      intronic
chr10:99481796(+) A-I      intronic
chr10:99483807(+) A-I      intronic
chr10:99481433(+) A-I      intronic
chr10:99483811(+) A-I      intronic
chr10:99481638(+) A-I      intronic
chr10:99479123(+) A-I      intronic
chr10:99479130(+) A-I      intronic
chr10:99481634(+) A-I      intronic
chr10:99483818(+) A-I      intronic
chr10:99483826(+) A-I      intronic
chr10:99481643(+) A-I      intronic
chr10:99483828(+) A-I      intronic
chr10:99479173(+) A-I      intronic
chr10:99481757(+) A-I      intronic
chr10:99481759(+) A-I      intronic
chr10:99480320(+) A-I      intronic
chr10:99480329(+) A-I      intronic
chr10:99483563(+) A-I      intronic
chr10:99480340(+) A-I      intronic
chr10:99480355(+) A-I      intronic
chr10:99481608(+) A-I      intronic
chr10:99481635(+) A-I      intronic
chr10:99481583(+) A-I      intronic
chr10:99483608(+) A-I      intronic
chr10:99483842(+) A-I      intronic
chr10:99483833(+) A-I      intronic
chr10:99483834(+) A-I      intronic
chr10:99481743(+) A-I      intronic
chr10:99483862(+) A-I      intronic
chr10:99483858(+) A-I      intronic
chr10:99483838(+) A-I      intronic
chr10:99483839(+) A-I      intronic
chr10:99483405(+) A-I      intronic
chr10:99483652(+) A-I      intronic
chr10:99481055(+) A-I      intronic
chr10:99483414(+) A-I      intronic
chr10:99483799(+) A-I      intronic
chr10:99480709(+) A-I      intronic
chr10:99483977(+) A-I      intronic
chr10:99479081(+) A-I      intronic
chr10:99476081(+) A-I      intronic
chr10:99481781(+) A-I      intronic
chr10:99479088(+) A-I      intronic
chr10:99479093(+) A-I      intronic
chr10:99481267(+) A-I      intronic
chr10:99483591(+) A-I      intronic
chr10:99479117(+) A-I      intronic
chr10:99481780(+) A-I      intronic
chr10:99483575(+) A-I      intronic
chr10:99480954(+) A-I      intronic
chr10:99479175(+) A-I      intronic
chr10:99481375(+) A-I      intronic
chr10:99479183(+) A-I      intronic
chr10:99481353(+) A-I      intronic
chr10:99479231(+) A-I      intronic
chr10:99483760(+) A-I      intronic
chr10:99479243(+) A-I      intronic
chr10:99483740(+) A-I      intronic
chr10:99483406(+) A-I      intronic
chr10:99483475(+) A-I      intronic
chr10:99479254(+) A-I      intronic
chr10:99479256(+) A-I      intronic
chr10:99480112(+) A-I      intronic
chr10:99482719(+) A-I      intronic
chr10:99483474(+) A-I      intronic
chr10:99480282(+) A-I      intronic
chr10:99480310(+) A-I      intronic
chr10:99482602(+) A-I      intronic
chr10:99483451(+) A-I      intronic
chr10:99481782(+) A-I      intronic
chr10:99483755(+) A-I      intronic
chr10:99483605(+) A-I      intronic
chr10:99483432(+) A-I      intronic
chr10:99481749(+) A-I      intronic
chr10:99481135(+) A-I      intronic
chr10:99483756(+) A-I      intronic
chr10:99483627(+) A-I      intronic
chr10:99483976(+) A-I      intronic
chr10:99483389(+) A-I      intronic
chr10:99483630(+) A-I      intronic
chr10:99481134(+) A-I      intronic
chr10:99480938(+) A-I      intronic
chr10:99479991(+) A-I      intronic
chr10:99479297(+) A-I      intronic
chr10:99480330(+) A-I      intronic
chr10:99483582(+) A-I      intronic
chr10:99479316(+) A-I      intronic
chr10:99480128(+) A-I      intronic
chr10:99480139(+) A-I      intronic
chr10:99480396(+) A-I      intronic
chr10:99483383(+) A-I      intronic
chr10:99483734(+) A-I      intronic
chr10:99479239(+) A-I      intronic
chr10:99481080(+) A-I      intronic
chr10:99480080(+) A-I      intronic
chr10:99480068(+) A-I      intronic
chr10:99480179(+) A-I      intronic
chr10:99483909(+) A-I      intronic
chr10:99483490(+) A-I      intronic
chr10:99483581(+) A-I      intronic
chr10:99483892(+) A-I      intronic
chr10:99483669(+) A-I      intronic
chr10:99481760(+) A-I      intronic
chr10:99479308(+) A-I      intronic
chr10:99483595(+) A-I      intronic
chr10:99479111(+) A-I      intronic
chr10:99480060(+) A-I      intronic
chr10:99481316(+) A-I      intronic
chr10:99479967(+) A-I      intronic
chr10:99481730(+) A-I      intronic
chr10:99476071(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MARVELD1
chr10:99473027-99473028(+) m6A exon       25456834//24981863
chr10:99473502-99473503(+) m6A 5'UTR//intron       25456834//24981863
chr10:99474205-99474206(+) m6A 3'UTR//intron       24209618//24981863//22575960
chr10:99474306-99474307(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99474403-99474404(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99474466-99474467(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99474498-99474499(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99474510-99474511(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99474545-99474546(+) Y 3'UTR//exon//intron       26075521
chr10:99474550-99474551(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99474673-99474674(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99474810-99474811(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//22608085
chr10:99474914-99474915(+) m6A 3'UTR//intron       24284625//24209618//24981863
chr10:99475058-99475059(+) m6A 3'UTR//intron       24284625//24209618//24981863
chr10:99475083-99475084(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863
chr10:99475104-99475105(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863
chr10:99475124-99475125(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863
chr10:99475130-99475131(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863
chr10:99475176-99475177(+) m6A 3'UTR//intron       24284625//24209618//24981863
chr10:99475282-99475283(+) m6A 3'UTR//intron       24284625//24981863
chr10:99475497-99475498(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085
chr10:99475539-99475540(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085
chr10:99475545-99475546(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085
chr10:99475559-99475560(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085
chr10:99475698-99475699(+) m6A 3'UTR//exon       24284625//25456834
chr10:99477132-99477133(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085
chr10:99477218-99477219(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr10:99477241-99477242(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr10:99477268-99477269(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22608085
chr10:99477561-99477562(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99477570-99477571(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99477638-99477639(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99477689-99477690(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99477706-99477707(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99477749-99477750(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr10:99477834-99477835(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-762
Exosome Pooled sera     27278097
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Hepatoma cells     23771658
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
MARVELD1
Cytosol HeLa-S3 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-762
Gemcitabine 60750 Drug interaction    RC00007981
Imatinib 5291 Drug interaction    RC00007980
Bortezomib 387447 Drug interaction    RC00007983
5-Fluorouracil 3385 Drug interaction    RC00007979
Gefitinib 123631 Drug interaction    RC00007982
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-762
Crizotinib       11626560

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-762
Interactor2: MARVELD1

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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