Basic Information:

  VIRBase ID:  

HHID00099048

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-762:  MIMAT0010313          PDXK:  NM_003681     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-762	PDXK
miRBase Accession/Entrez ID	MIMAT0010313	8566
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C21orf124//C21orf97//HEL-S-1a//HMSN6C//PKH//PNK//PRED79

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-762	rs1379218716 chr16:30893951    G/A rs1401867087 chr16:30893964    G/A rs1406702631 chr16:30893966    G/A rs1407433182 chr16:30893961    C/G rs374396561 chr16:30893962    C/T rs751832217 chr16:30893968    C/G rs752364708 chr16:30893961    CCGGGGCCGAGCCCGCGG/C rs755205907 chr16:30893971    G/T rs758841312 chr16:30893963    G/A rs758841312 chr16:30893963    G/C rs1241251631 chr16:30893956    T/A rs1288563923 chr16:30893956    T/TGGGGCC rs1307177311 chr16:30893953    G/A rs750763225 chr16:30893954    G/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PDXK	chr21:45166574(+) A-I      intronic chr21:45166562(+) A-I      intronic chr21:45162556(+) A-I      intronic chr21:45150705(+) A-I      intronic chr21:45150678(+) A-I      intronic chr21:45166580(+) A-I      intronic chr21:45145610(+) A-I      intronic chr21:45145598(+) A-I      intronic chr21:45145535(+) A-I      intronic chr21:45143104(+) A-I      intronic chr21:45143086(+) A-I      intronic chr21:45149718(+) A-I      intronic chr21:45149714(+) A-I      intronic chr21:45149696(+) A-I      intronic chr21:45145648(+) A-I      intronic chr21:45145620(+) A-I      intronic chr21:45162146(+) A-I      intronic chr21:45152745(+) A-I      intronic chr21:45150152(+) A-I      intronic chr21:45145545(+) A-I      intronic chr21:45142904(+) A-I      intronic chr21:45142926(+) A-I      intronic chr21:45142966(+) A-I      intronic chr21:45143178(+) A-I      intronic chr21:45144692(+) A-I      intronic chr21:45144955(+) A-I      intronic chr21:45144988(+) A-I      intronic chr21:45145110(+) A-I      intronic chr21:45145145(+) A-I      intronic chr21:45145541(+) A-I      intronic chr21:45145640(+) A-I      intronic chr21:45149710(+) A-I      intronic chr21:45149726(+) A-I      intronic chr21:45149731(+) A-I      intronic chr21:45150148(+) A-I      intronic chr21:45150207(+) A-I      intronic chr21:45145616(+) A-I      intronic chr21:45150229(+) A-I      intronic chr21:45150246(+) A-I      intronic chr21:45150267(+) A-I      intronic chr21:45150702(+) A-I      intronic chr21:45150709(+) A-I      intronic chr21:45162122(+) A-I      intronic chr21:45162130(+) A-I      intronic chr21:45162263(+) A-I      intronic chr21:45166799(+) A-I      intronic chr21:45166888(+) A-I      intronic chr21:45166944(+) A-I      intronic chr21:45142895(+) A-I      intronic chr21:45169183(+) A-I      intronic chr21:45162557(+) A-I      intronic chr21:45149686(+) A-I      intronic chr21:45142901(+) A-I      intronic chr21:45162511(+) A-I      intronic chr21:45162484(+) A-I      intronic chr21:45150693(+) A-I      intronic chr21:45162315(+) A-I      intronic chr21:45142999(+) A-I      intronic chr21:45162568(+) A-I      intronic chr21:45166362(+) A-I      intronic chr21:45166405(+) A-I      intronic chr21:45166590(+) A-I      intronic chr21:45166934(+) A-I      intronic chr21:45143139(+) A-I      intronic chr21:45145149(+) A-I      intronic chr21:45166982(+) A-I      intronic chr21:45144544(+) A-I      intronic chr21:45150064(+) A-I      intronic chr21:45143089(+) A-I      intronic chr21:45150281(+) A-I      intronic chr21:45145571(+) A-I      intronic chr21:45162116(+) A-I      intronic chr21:45143239(+) A-I      intronic chr21:45144490(+) A-I      intronic chr21:45152757(+) A-I      intronic chr21:45146569(+) A-I      intronic chr21:45167023(+) A-I      intronic chr21:45166568(+) A-I      intronic chr21:45145125(+) A-I      intronic chr21:45146339(+) A-I      intronic chr21:45168166(+) A-I      intronic chr21:45149757(+) A-I      intronic chr21:45145572(+) A-I      intronic chr21:45143140(+) A-I      intronic chr21:45150969(+) A-I      intronic chr21:45152890(+) A-I      intronic chr21:45168317(+) A-I      intronic chr21:45145129(+) A-I      intronic chr21:45150715(+) A-I      intronic chr21:45150977(+) A-I      intronic chr21:45144663(+) A-I      intronic chr21:45144561(+) A-I      intronic chr21:45145702(+) A-I      intronic chr21:45144706(+) A-I      intronic chr21:45166381(+) A-I      intronic chr21:45143181(+) A-I      intronic chr21:45149625(+) A-I      intronic chr21:45144508(+) A-I      intronic chr21:45162503(+) A-I      intronic chr21:45146256(+) A-I      intronic chr21:45150159(+) A-I      intronic chr21:45150579(+) A-I      intronic chr21:45150905(+) A-I      intronic chr21:45168277(+) A-I      intronic chr21:45144503(+) A-I      intronic chr21:45142993(+) A-I      intronic chr21:45168318(+) A-I      intronic chr21:45150055(+) A-I      intronic chr21:45143316(+) A-I      intronic chr21:45145679(+) A-I      intronic chr21:45166780(+) A-I      intronic chr21:45144704(+) A-I      intronic chr21:45144710(+) A-I      intronic chr21:45149750(+) A-I      intronic chr21:45150689(+) A-I      intronic chr21:45146581(+) A-I      intronic chr21:45152660(+) A-I      intronic chr21:45146250(+) A-I      intronic chr21:45143193(+) A-I      intronic chr21:45144933(+) A-I      intronic chr21:45162733(+) A-I      intronic chr21:45162690(+) A-I      intronic chr21:45166443(+) A-I      intronic chr21:45146489(+) A-I      intronic chr21:45145154(+) A-I      intronic chr21:45143242(+) A-I      intronic chr21:45144637(+) A-I      intronic chr21:45180197(+) A-I      3'UTR chr21:45180345(+) A-I      3'UTR chr21:45149606(+) A-I      intronic chr21:45145169(+) A-I      intronic chr21:45150081(+) A-I      intronic chr21:45166370(+) A-I      intronic chr21:45166380(+) A-I      intronic chr21:45144642(+) A-I      intronic chr21:45162559(+) A-I      intronic chr21:45166896(+) A-I      intronic chr21:45145433(+) A-I      intronic chr21:45168248(+) A-I      intronic chr21:45167001(+) A-I      intronic chr21:45150729(+) A-I      intronic chr21:45166804(+) A-I      intronic chr21:45143165(+) A-I      intronic chr21:45162646(+) A-I      intronic chr21:45143276(+) A-I      intronic chr21:45143175(+) A-I      intronic chr21:45149804(+) A-I      intronic chr21:45150136(+) A-I      intronic chr21:45166535(+) A-I      intronic chr21:45162682(+) A-I      intronic chr21:45152903(+) A-I      intronic chr21:45162416(+) A-I      intronic chr21:45152677(+) A-I      intronic chr21:45162190(+) A-I      intronic chr21:45144541(+) A-I      intronic chr21:45152767(+) A-I      intronic chr21:45162186(+) A-I      intronic chr21:45166316(+) A-I      intronic chr21:45150606(+) A-I      intronic chr21:45142858(+) A-I      intronic chr21:45143225(+) A-I      intronic chr21:45149704(+) A-I      intronic chr21:45144465(+) A-I      intronic chr21:45142823(+) A-I      intronic chr21:45143136(+) A-I      intronic chr21:45150571(+) A-I      intronic chr21:45166742(+) A-I      intronic chr21:45142762(+) A-I      intronic chr21:45162324(+) A-I      intronic chr21:45144949(+) A-I      intronic chr21:45150087(+) A-I      intronic chr21:45145083(+) A-I      intronic chr21:45150653(+) A-I      intronic chr21:45165668(+) A-I      intronic chr21:45169247(+) A-I      intronic chr21:45150241(+) A-I      intronic chr21:45144687(+) A-I      intronic chr21:45149679(+) A-I      intronic chr21:45150100(+) A-I      intronic chr21:45166898(+) A-I      intronic chr21:45146498(+) A-I      intronic chr21:45152891(+) A-I      intronic chr21:45143302(+) A-I      intronic chr21:45150978(+) A-I      intronic chr21:45149566(+) A-I      intronic chr21:45144481(+) A-I      intronic chr21:45162525(+) A-I      intronic chr21:45143116(+) A-I      intronic chr21:45166375(+) A-I      intronic chr21:45152740(+) A-I      intronic chr21:45143153(+) A-I      intronic chr21:45142768(+) A-I      intronic chr21:45150739(+) A-I      intronic chr21:45149745(+) A-I      intronic chr21:45150573(+) A-I      intronic chr21:45162291(+) A-I      intronic chr21:45162724(+) A-I      intronic chr21:45144619(+) A-I      intronic chr21:45143271(+) A-I      intronic chr21:45145186(+) A-I      intronic chr21:45143092(+) A-I      intronic chr21:45145124(+) A-I      intronic chr21:45142798(+) A-I      intronic chr21:45142984(+) A-I      intronic chr21:45168247(+) A-I      intronic chr21:45144659(+) A-I      intronic chr21:45144950(+) A-I      intronic chr21:45146342(+) A-I      intronic chr21:45162698(+) A-I      intronic chr21:45145024(+) A-I      intronic chr21:45150913(+) A-I      intronic chr21:45150035(+) A-I      intronic chr21:45150979(+) A-I      intronic chr21:45150190(+) A-I      intronic chr21:45152811(+) A-I      intronic chr21:45162576(+) A-I      intronic chr21:45152829(+) A-I      intronic chr21:45145641(+) A-I      intronic chr21:45144467(+) A-I      intronic chr21:45149678(+) A-I      intronic chr21:45150785(+) A-I      intronic chr21:45144601(+) A-I      intronic chr21:45166764(+) A-I      intronic chr21:45145436(+) A-I      intronic chr21:45166528(+) A-I      intronic chr21:45146364(+) A-I      intronic chr21:45166441(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PDXK	chr21:45167001(+) A-I intron -    15545495 chr21:45150573(+) A-I intron -    22327324 chr21:45150579(+) A-I intron -    22327324 chr21:45144481(+) A-I intron -    22028664 chr21:45144490(+) A-I intron -    22028664 chr21:45144492(+) A-I intron -    22028664 chr21:45144503(+) A-I intron -    22028664 chr21:45144508(+) A-I intron -    22028664 chr21:45144541(+) A-I intron -    22028664 chr21:45144561(+) A-I intron -    22028664 chr21:45144601(+) A-I intron -    22028664 chr21:45144619(+) A-I intron -    22028664 chr21:45144663(+) A-I intron -    22028664 chr21:45144687(+) A-I intron -    22028664 chr21:45144704(+) A-I intron -    22028664 chr21:45144706(+) A-I intron -    22028664 chr21:45144710(+) A-I intron -    22028664 chr21:45143089(+) A-G intron -    22484847 chr21:45145169(+) A-G intron -    22484847 chr21:45145413(+) A-G intron -    22484847 chr21:45146193(+) A-G intron -    22484847 chr21:45146250(+) A-G intron -    22484847 chr21:45149619(+) A-G intron -    22484847 chr21:45149678(+) A-G intron -    22484847 chr21:45150571(+) A-G intron -    22484847 chr21:45150573(+) A-G intron -    22484847 chr21:45150579(+) A-G intron -    22484847 chr21:45150601(+) A-G intron -    22484847 chr21:45150633(+) A-G intron -    22484847 chr21:45150913(+) A-G intron -    22484847 chr21:45162416(+) A-G intron -    22484847 chr21:45166380(+) A-G intron -    22484847 chr21:45166528(+) A-G intron -    22484847 chr21:45166568(+) A-G intron -    22484847 chr21:45166804(+) A-G intron -    22484847 chr21:45166812(+) A-G intron -    22484847 chr21:45166896(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PDXK	chr21:45138981-45138982(+) m6A 5'UTR       24209618//25456834//24981863 chr21:45139130-45139131(+) m6A 5'UTR//exon       24209618//24981863//27371828//27773536//22575960 chr21:45152136-45152137(+) m6A 5'UTR//exon//intron       24284625//24981863 chr21:45152190-45152191(+) m6A 5'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085 chr21:45152266-45152267(+) m6A CDS//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:45152283-45152284(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45157045-45157046(+) m6A 3'UTR//CDS//intron       24284625 chr21:45157058-45157059(+) m6A 3'UTR//CDS//intron       24284625 chr21:45157360-45157361(+) m6A 3'UTR//CDS//intron       24284625//25456834 chr21:45157457-45157458(+) m6A 3'UTR//CDS//intron       24284625//25456834//24981863//22575960//22608085 chr21:45157517-45157518(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:45157569-45157570(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:45157611-45157612(+) m6A 3'UTR//exon//intron       25456834//24981863//22575960//22608085 chr21:45157639-45157640(+) m6A 3'UTR//exon//intron       25456834//24981863//22575960//22608085 chr21:45157696-45157697(+) m6A 3'UTR//exon//intron       25456834//24981863//22608085 chr21:45157743-45157744(+) m6A 3'UTR//exon//intron       25456834//24981863//22608085 chr21:45157843-45157844(+) m6A 3'UTR//exon//intron       24981863 chr21:45157904-45157905(+) m6A 3'UTR//exon//intron       24981863 chr21:45158010-45158011(+) m6A 3'UTR//exon//intron       24284625//24981863//22608085 chr21:45158125-45158126(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45158131-45158132(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45158145-45158146(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45158161-45158162(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45158207-45158208(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:45158228-45158229(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:45158235-45158236(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:45158250-45158251(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:45158362-45158363(+) m6A 3'UTR//exon//intron       24284625//24981863//22575960//22608085 chr21:45158382-45158383(+) m6A 3'UTR//exon//intron       24284625//24981863//22575960//22608085 chr21:45158464-45158465(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:45158484-45158485(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:45158505-45158506(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:45158525-45158526(+) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22575960//22608085 chr21:45158532-45158533(+) m6A 3'UTR//exon//intron       24284625//24981863//22575960//22608085 chr21:45158536-45158537(+) m6A 3'UTR//exon//intron       22575960 chr21:45158626-45158627(+) m6A 3'UTR//exon//intron       24284625//24981863//22575960//22608085 chr21:45163616-45163617(+) m6A CDS//exon//intron       22575960 chr21:45163643-45163644(+) m6A CDS//exon//intron       22575960 chr21:45163670-45163671(+) m6A CDS//exon//intron       22575960 chr21:45164445-45164446(+) m6A exon//intron       22575960 chr21:45164493-45164494(+) m6A exon//intron       22608085 chr21:45167002-45167003(+) m6A exon//intron       22575960 chr21:45167017-45167018(+) m6A exon//intron       22575960 chr21:45167036-45167037(+) m6A exon//intron       22575960 chr21:45168888-45168889(+) m6A CDS//exon       22575960 chr21:45168930-45168931(+) m6A CDS//exon       22575960 chr21:45172405-45172406(+) m6A CDS//exon       22575960 chr21:45173505-45173506(+) m6A CDS//exon       22575960 chr21:45173544-45173545(+) m6A CDS//exon       22575960 chr21:45173573-45173574(+) m6A CDS//exon       22575960 chr21:45175366-45175367(+) m6A exon//intron       22575960 chr21:45175593-45175594(+) m6A CDS//exon       24284625//22575960 chr21:45175626-45175627(+) m6A CDS//exon       24284625//22575960 chr21:45175900-45175901(+) m6A CDS//exon       24284625//22575960 chr21:45175909-45175910(+) m6A CDS//exon       24284625//22575960 chr21:45176006-45176007(+) m6A 3'UTR//exon       24284625//22575960 chr21:45176039-45176040(+) m6A 3'UTR//exon       24284625 chr21:45176154-45176155(+) m6A 3'UTR       24284625 chr21:45176455-45176456(+) m6A 3'UTR       22575960 chr21:45176555-45176556(+) m6A 3'UTR       24284625 chr21:45176576-45176577(+) m6A 3'UTR       24284625 chr21:45176614-45176615(+) m6A 3'UTR       24284625 chr21:45176634-45176635(+) m6A 3'UTR       24284625 chr21:45176743-45176744(+) m6A 3'UTR       24284625//22575960 chr21:45176857-45176858(+) m6A 3'UTR       24284625//22575960 chr21:45176862-45176863(+) m6A 3'UTR       24284625//22575960 chr21:45177252-45177253(+) m6A 3'UTR       - chr21:45177317-45177318(+) m6A 3'UTR       22575960 chr21:45177417-45177418(+) m6A 3'UTR       22575960 chr21:45177486-45177487(+) m6A 3'UTR       24284625 chr21:45177586-45177587(+) m6A 3'UTR       24284625 chr21:45177622-45177623(+) m6A 3'UTR       24284625 chr21:45178103-45178104(+) m6A 3'UTR       24284625 chr21:45178189-45178190(+) m6A 3'UTR       24284625 chr21:45178224-45178225(+) m6A 3'UTR       24284625 chr21:45178358-45178359(+) m6A 3'UTR       24284625 chr21:45178373-45178374(+) m6A 3'UTR       24284625 chr21:45179511-45179512(+) m6A 3'UTR       24284625 chr21:45179549-45179550(+) m6A 3'UTR       24284625 chr21:45179563-45179564(+) m6A 3'UTR       24284625 chr21:45179570-45179571(+) m6A 3'UTR       24284625 chr21:45180279-45180280(+) m6A 3'UTR       24284625 chr21:45180377-45180378(+) m6A 3'UTR       24284625 chr21:45180442-45180443(+) m6A 3'UTR       24284625 chr21:45180541-45180542(+) Tm 3'UTR       - chr21:45180633-45180634(+) m6A 3'UTR       24284625 chr21:45181071-45181072(+) m6A 3'UTR       24284625 chr21:45181114-45181115(+) m6A 3'UTR       24284625 chr21:45181198-45181199(+) m6A 3'UTR       24284625 chr21:45181283-45181284(+) m6A 3'UTR       24284625//25456834//24981863//22575960 chr21:45181326-45181327(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45181398-45181399(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45181414-45181415(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45181421-45181422(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45181550-45181551(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45181593-45181594(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45181622-45181623(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45181664-45181665(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr21:45181864-45181865(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr21:45181897-45181898(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr21:45181902-45181903(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-762	Exosome Pooled sera     27278097 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Hepatoma cells     23771658 Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	PDXK	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-762	Gemcitabine 60750 Drug interaction    RC00007981 Imatinib 5291 Drug interaction    RC00007980 Bortezomib 387447 Drug interaction    RC00007983 5-Fluorouracil 3385 Drug interaction    RC00007979 Gefitinib 123631 Drug interaction    RC00007982

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsa-miR-762	Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-762
Interactor2: PDXK

Evidence Support:

Weak-Evidence	Illumina sequencing
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32223537	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Calu-3 cells	Interactor2 expression	Downregulation
Description	The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.