Detail Information

Basic Information:


  VIRBase ID:  

HHID00099013

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-762:           ARHGAP1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-762 ARHGAP1
miRBase
Accession/Entrez ID		 MIMAT0010313 392
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CDC42GAP//p50rhoGAP//RHOGAP//RHOGAP1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-762
rs1379218716 chr16:30893951    G/A
rs1401867087 chr16:30893964    G/A
rs1406702631 chr16:30893966    G/A
rs1407433182 chr16:30893961    C/G
rs374396561 chr16:30893962    C/T
rs751832217 chr16:30893968    C/G
rs752364708 chr16:30893961    CCGGGGCCGAGCCCGCGG/C
rs755205907 chr16:30893971    G/T
rs758841312 chr16:30893963    G/A
rs758841312 chr16:30893963    G/C
rs1241251631 chr16:30893956    T/A
rs1288563923 chr16:30893956    T/TGGGGCC
rs1307177311 chr16:30893953    G/A
rs750763225 chr16:30893954    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ARHGAP1
chr11:46707618(-) A-I      intronic
chr11:46707059(-) A-I      intronic
chr11:46705256(-) A-I      intronic
chr11:46707664(-) A-I      intronic
chr11:46704673(-) A-I      intronic
chr11:46704700(-) A-I      intronic
chr11:46704713(-) A-I      intronic
chr11:46706594(-) A-I      intronic
chr11:46707681(-) A-I      intronic
chr11:46704720(-) A-I      intronic
chr11:46707046(-) A-I      intronic
chr11:46707627(-) A-I      intronic
chr11:46707717(-) A-I      intronic
chr11:46712973(-) A-I      intronic
chr11:46713126(-) A-I      intronic
chr11:46706538(-) A-I      intronic
chr11:46706446(-) A-I      intronic
chr11:46708241(-) A-I      intronic
chr11:46711362(-) A-I      intronic
chr11:46711356(-) A-I      intronic
chr11:46711340(-) A-I      intronic
chr11:46704687(-) A-I      intronic
chr11:46711239(-) A-I      intronic
chr11:46704198(-) A-I      intronic
chr11:46711158(-) A-I      intronic
chr11:46711126(-) A-I      intronic
chr11:46710252(-) A-I      intronic
chr11:46710188(-) A-I      intronic
chr11:46710064(-) A-I      intronic
chr11:46705403(-) A-I      intronic
chr11:46705328(-) A-I      intronic
chr11:46708054(-) A-I      intronic
chr11:46710388(-) A-I      intronic
chr11:46707760(-) A-I      intronic
chr11:46706500(-) A-I      intronic
chr11:46704085(-) A-I      intronic
chr11:46714375(-) A-I      intronic
chr11:46707607(-) A-I      intronic
chr11:46704122(-) A-I      intronic
chr11:46710297(-) A-I      intronic
chr11:46706470(-) A-I      intronic
chr11:46710086(-) A-I      intronic
chr11:46705391(-) A-I      intronic
chr11:46706974(-) A-I      intronic
chr11:46707038(-) A-I      intronic
chr11:46704825(-) A-I      intronic
chr11:46707104(-) A-I      intronic
chr11:46707353(-) A-I      intronic
chr11:46705383(-) A-I      intronic
chr11:46704860(-) A-I      intronic
chr11:46706945(-) A-I      intronic
chr11:46707429(-) A-I      intronic
chr11:46705339(-) A-I      intronic
chr11:46707633(-) A-I      intronic
chr11:46705288(-) A-I      intronic
chr11:46705319(-) A-I      intronic
chr11:46706569(-) A-I      intronic
chr11:46706556(-) A-I      intronic
chr11:46704890(-) A-I      intronic
chr11:46710160(-) A-I      intronic
chr11:46707701(-) A-I      intronic
chr11:46707032(-) A-I      intronic
chr11:46705331(-) A-I      intronic
chr11:46706489(-) A-I      intronic
chr11:46711361(-) A-I      intronic
chr11:46710428(-) A-I      intronic
chr11:46711737(-) A-I      intronic
chr11:46710376(-) A-I      intronic
chr11:46706905(-) A-I      intronic
chr11:46714330(-) A-I      intronic
chr11:46707071(-) A-I      intronic
chr11:46704811(-) A-I      intronic
chr11:46707768(-) A-I      intronic
chr11:46704201(-) A-I      intronic
chr11:46706498(-) A-I      intronic
chr11:46706940(-) A-I      intronic
chr11:46706970(-) A-I      intronic
chr11:46715094(-) A-I      intronic
chr11:46714674(-) A-I      intronic
chr11:46703155(-) A-I      intronic
chr11:46715179(-) A-I      intronic
chr11:46711758(-) A-I      intronic
chr11:46711918(-) A-I      intronic
chr11:46707367(-) A-I      intronic
chr11:46706494(-) A-I      intronic
chr11:46712037(-) A-I      intronic
chr11:46706561(-) A-I      intronic
chr11:46703991(-) A-I      intronic
chr11:46707630(-) A-I      intronic
chr11:46704086(-) A-I      intronic
chr11:46712071(-) A-I      intronic
chr11:46703092(-) A-I      intronic
chr11:46704112(-) A-I      intronic
chr11:46710215(-) A-I      intronic
chr11:46710510(-) A-I      intronic
chr11:46712907(-) A-I      intronic
chr11:46712897(-) A-I      intronic
chr11:46707784(-) A-I      intronic
chr11:46704792(-) A-I      intronic
chr11:46710146(-) A-I      intronic
chr11:46703977(-) A-I      intronic
chr11:46710522(-) A-I      intronic
chr11:46707070(-) A-I      intronic
chr11:46710582(-) A-I      intronic
chr11:46707109(-) A-I      intronic
chr11:46710124(-) A-I      intronic
chr11:46707042(-) A-I      intronic
chr11:46706394(-) A-I      intronic
chr11:46707719(-) A-I      intronic
chr11:46707714(-) A-I      intronic
chr11:46705440(-) A-I      intronic
chr11:46704151(-) A-I      intronic
chr11:46710571(-) A-I      intronic
chr11:46707497(-) A-I      intronic
chr11:46704068(-) A-I      intronic
chr11:46706381(-) A-I      intronic
chr11:46713244(-) A-I      intronic
chr11:46707101(-) A-I      intronic
chr11:46705384(-) A-I      intronic
chr11:46713195(-) A-I      intronic
chr11:46704733(-) A-I      intronic
chr11:46712055(-) A-I      intronic
chr11:46710110(-) A-I      intronic
chr11:46705363(-) A-I      intronic
chr11:46704231(-) A-I      intronic
chr11:46710590(-) A-I      intronic
chr11:46704836(-) A-I      intronic
chr11:46715088(-) A-I      intronic
chr11:46707624(-) A-I      intronic
chr11:46705293(-) A-I      intronic
chr11:46707708(-) A-I      intronic
chr11:46710292(-) A-I      intronic
chr11:46706526(-) A-I      intronic
chr11:46706475(-) A-I      intronic
chr11:46706490(-) A-I      intronic
chr11:46707771(-) A-I      intronic
chr11:46704187(-) A-I      intronic
chr11:46721707(-) A-I      intronic
chr11:46706472(-) A-I      intronic
chr11:46707645(-) A-I      intronic
chr11:46703263(-) A-I      intronic
chr11:46705296(-) A-I      intronic
chr11:46706555(-) A-I      intronic
chr11:46707404(-) A-I      intronic
chr11:46710442(-) A-I      intronic
chr11:46710231(-) A-I      intronic
chr11:46707763(-) A-I      intronic
chr11:46707713(-) A-I      intronic
chr11:46711294(-) A-I      intronic
chr11:46704110(-) A-I      intronic
chr11:46707646(-) A-I      intronic
chr11:46706975(-) A-I      intronic
chr11:46706943(-) A-I      intronic
chr11:46713078(-) A-I      intronic
chr11:46704229(-) A-I      intronic
chr11:46705355(-) A-I      intronic
chr11:46704765(-) A-I      intronic
chr11:46706393(-) A-I      intronic
chr11:46707711(-) A-I      intronic
chr11:46707339(-) A-I      intronic
chr11:46704147(-) A-I      intronic
chr11:46703157(-) A-I      intronic
chr11:46706980(-) A-I      intronic
chr11:46707673(-) A-I      intronic
chr11:46707016(-) A-I      intronic
chr11:46710451(-) A-I      intronic
chr11:46707720(-) A-I      intronic
chr11:46707385(-) A-I      intronic
chr11:46707631(-) A-I      intronic
chr11:46703990(-) A-I      intronic
chr11:46711295(-) A-I      intronic
chr11:46710129(-) A-I      intronic
chr11:46703239(-) A-I      intronic
chr11:46707006(-) A-I      intronic
chr11:46704152(-) A-I      intronic
chr11:46721134(-) A-I      intronic
chr11:46714327(-) A-I      intronic
chr11:46704884(-) A-I      intronic
chr11:46704686(-) A-I      intronic
chr11:46715107(-) A-I      intronic
chr11:46710298(-) A-I      intronic
chr11:46706516(-) A-I      intronic
chr11:46704102(-) A-I      intronic
chr11:46711335(-) A-I      intronic
chr11:46711759(-) A-I      intronic
chr11:46706466(-) A-I      intronic
chr11:46710235(-) A-I      intronic
chr11:46714300(-) A-I      intronic
chr11:46704692(-) A-I      intronic
chr11:46707496(-) A-I      intronic
chr11:46707705(-) A-I      intronic
chr11:46707148(-) A-I      intronic
chr11:46703989(-) A-I      intronic
chr11:46710466(-) A-I      intronic
chr11:46705276(-) A-I      intronic
chr11:46707002(-) A-I      intronic
chr11:46707584(-) A-I      intronic
chr11:46707072(-) A-I      intronic
chr11:46707314(-) A-I      intronic
chr11:46712963(-) A-I      intronic
chr11:46703211(-) A-I      intronic
chr11:46706468(-) A-I      intronic
chr11:46714985(-) A-I      intronic
chr11:46704717(-) A-I      intronic
chr11:46710170(-) A-I      intronic
chr11:46699080(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ARHGAP1
chr11:46699080(-) A-I exon 3'UTR    19478186
chr11:46704687(-) A-I intron -    21960545
chr11:46707705(-) A-I intron -    21960545
chr11:46706943(-) A-I intron -    21960545
chr11:46704229(-) A-G intron -    22484847
chr11:46704717(-) A-G intron -    22484847
chr11:46704792(-) A-G intron -    22484847
chr11:46706475(-) A-G intron -    22484847
chr11:46707032(-) A-G intron -    22484847
chr11:46707070(-) A-G intron -    22484847
chr11:46707630(-) A-G intron -    22484847
chr11:46707705(-) A-G intron -    22484847
chr11:46707768(-) A-G intron -    22484847
chr11:46710215(-) A-G intron -    22484847
chr11:46710231(-) A-G intron -    22484847
chr11:46710297(-) A-G intron -    22484847
chr11:46713195(-) A-G intron -    22484847
chr11:46713244(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ARHGAP1
chr11:46699197-46699198(-) m6A 3'UTR       27773535
chr11:46699380-46699381(-) m6A 3'UTR       24209618
chr11:46699856-46699857(-) m6A 3'UTR       24284625//24209618//27773535//22575960
chr11:46699903-46699904(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960
chr11:46700001-46700002(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960
chr11:46700160-46700161(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr11:46700311-46700312(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960
chr11:46700369-46700370(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960
chr11:46700538-46700539(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr11:46700585-46700586(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr11:46700602-46700603(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr11:46703711-46703712(-) m6A CDS//intron       27773535
chr11:46708305-46708306(-) m6A exon//intron       27773535
chr11:46716640-46716641(-) m6A exon//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-762
Exosome Pooled sera     27278097
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Hepatoma cells     23771658
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
ARHGAP1
Chromatin K562 cells     -
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-762
Gemcitabine 60750 Drug interaction    RC00007981
Imatinib 5291 Drug interaction    RC00007980
Bortezomib 387447 Drug interaction    RC00007983
5-Fluorouracil 3385 Drug interaction    RC00007979
Gefitinib 123631 Drug interaction    RC00007982
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-762
Crizotinib       11626560

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-762
Interactor2: ARHGAP1

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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