Detail Information

Basic Information:


  VIRBase ID:  

HHID00099006

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1275:           BCL9L:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1275 BCL9L
miRBase
Accession/Entrez ID		 MIMAT0005929 283149
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - B9L//BCL9-2//DLNB11

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1275
rs372458638 chr6:34000019    A/AAAACC
rs377188203 chr6:34000023    C/T
rs557928121 chr6:34000019    A/T
rs758811783 chr6:34000022    G/A
rs761034364 chr6:34000017    AGAC/A
rs370361021 chr6:34000029    C/A
rs370361021 chr6:34000029    C/T
rs374728385 chr6:34000032    C/A
rs374728385 chr6:34000032    C/G
rs747378297 chr6:34000028    C/T
rs772691699 chr6:34000033    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR BCL9L
chr11:118796291(-) A-I      5'UTR
chr11:118777399(-) A-I      intronic
chr11:118777471(-) A-I      intronic
chr11:118777474(-) A-I      intronic
chr11:118776903(-) A-I      intronic
chr11:118776899(-) A-I      intronic
chr11:118777481(-) A-I      intronic
chr11:118777480(-) A-I      intronic
chr11:118780025(-) A-I      intronic
chr11:118776026(-) A-I      intronic
chr11:118776897(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase BCL9L
chr11:118765904-118765905(-) m6A 3'UTR       25456834
chr11:118765983-118765984(-) m6A 3'UTR       25456834
chr11:118767165-118767166(-) m6A 3'UTR       24284625//27773535
chr11:118767175-118767176(-) m6A 3'UTR       24284625//27773535
chr11:118767407-118767408(-) m6A 3'UTR       22575960
chr11:118767472-118767473(-) m6A 3'UTR       22575960
chr11:118767492-118767493(-) m6A 3'UTR       22575960
chr11:118767509-118767510(-) m6A 3'UTR       22575960
chr11:118767824-118767825(-) m6A 3'UTR       24284625//27773535
chr11:118767888-118767889(-) m6A 3'UTR       24284625//27773535
chr11:118768454-118768455(-) m6A 3'UTR       27773535
chr11:118768753-118768754(-) m6A 3'UTR       24284625//27773535
chr11:118768890-118768891(-) m6A 3'UTR       24284625
chr11:118768975-118768976(-) m6A 3'UTR       24284625
chr11:118769178-118769179(-) m6A CDS       24284625//24209618//25456834//24981863//22575960
chr11:118769223-118769224(-) m6A CDS       24284625//24209618//25456834//24981863//22575960
chr11:118769416-118769417(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118769438-118769439(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118769515-118769516(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118769532-118769533(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118769541-118769542(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118769583-118769584(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118769829-118769830(-) m6A CDS       24284625//24981863//27371828//22575960
chr11:118770024-118770025(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118770043-118770044(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118770147-118770148(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960
chr11:118770180-118770181(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960
chr11:118770706-118770707(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118770786-118770787(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960
chr11:118770804-118770805(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960
chr11:118770834-118770835(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960
chr11:118771331-118771332(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960
chr11:118771359-118771360(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960
chr11:118771383-118771384(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960
chr11:118771538-118771539(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960
chr11:118771582-118771583(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960
chr11:118771704-118771705(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960
chr11:118771731-118771732(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118771750-118771751(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118771848-118771849(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118771866-118771867(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118771889-118771890(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118771980-118771981(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085
chr11:118772037-118772038(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085
chr11:118772103-118772104(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:118772109-118772110(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:118772115-118772116(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:118772133-118772134(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:118772166-118772167(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:118772342-118772343(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085
chr11:118772487-118772488(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:118772507-118772508(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:118772526-118772527(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:118772533-118772534(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:118772549-118772550(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:118772666-118772667(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:118772808-118772809(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118772843-118772844(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr11:118772919-118772920(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960
chr11:118772946-118772947(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960
chr11:118772964-118772965(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960
chr11:118773025-118773026(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960
chr11:118773050-118773051(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118773172-118773173(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27371828//22575960
chr11:118773204-118773205(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27371828//22575960
chr11:118773342-118773343(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//22575960
chr11:118773409-118773410(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27371828//22575960
chr11:118773453-118773454(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27371828//22575960
chr11:118773465-118773466(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27371828//22575960
chr11:118773590-118773591(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960
chr11:118774107-118774108(-) m6A CDS//intron       24284625//24209618
chr11:118774145-118774146(-) m6A CDS//intron       24284625//24209618//27773535//22575960
chr11:118778229-118778230(-) m6A CDS//exon//intron       24284625//24209618//27773535//22575960
chr11:118778234-118778235(-) m6A CDS//exon//intron       24284625//24209618//27773535//22575960
chr11:118779005-118779006(-) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22575960
chr11:118779031-118779032(-) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//27371828//22575960
chr11:118779049-118779050(-) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//27371828//22575960
chr11:118779103-118779104(-) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//27371828//22575960
chr11:118779154-118779155(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr11:118779195-118779196(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828
chr11:118779202-118779203(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828
chr11:118779242-118779243(-) m6A CDS//exon//intron       24284625//24209618//24981863//26404942//27773535//27371828
chr11:118780626-118780627(-) m6A CDS//intron       24284625//24981863//27773535//22575960
chr11:118781465-118781466(-) m6A 5'UTR//intron       -
chr11:118789571-118789572(-) m6A 5'UTR//intron       24284625//27371828
chr11:118795964-118795965(-) m6A 5'UTR       24284625//27371828
chr11:118796025-118796026(-) m6A 5'UTR       24284625//24209618//27371828
chr11:118796151-118796152(-) m6A 5'UTR       24284625//24209618//22575960
chr11:118796243-118796244(-) m6A 5'UTR       24209618//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1275
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
Mitochondrion HeLa cells     27396686
Mitochondrion HeLa cells     27563705
Mitochondrion Cell line (HeLa)     21695135
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleolus HeLa cells     23940654
BCL9L
Chromatin K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-1275
Gemcitabine 60750 Drug interaction    RC00007825
Vincristine 5978 Drug interaction    RC00007823
Eloxatine 5310940 Drug interaction    RC00007826
Paclitaxel 36314 Drug interaction    RC00007824
5-Fluorouracil 3385 Drug interaction    RC00007822
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007821
Marine fungal metabolite 1386A - Drug interaction    RC00007827
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-1275
l-685,458       5479543

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1275
Interactor2: BCL9L

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

Starting a new search, please wait ...