Detail Information

Basic Information:


  VIRBase ID:  

HHID00099004

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1275:           SAMD14:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1275 SAMD14
miRBase
Accession/Entrez ID		 MIMAT0005929 201191
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1275
rs372458638 chr6:34000019    A/AAAACC
rs377188203 chr6:34000023    C/T
rs557928121 chr6:34000019    A/T
rs758811783 chr6:34000022    G/A
rs761034364 chr6:34000017    AGAC/A
rs370361021 chr6:34000029    C/A
rs370361021 chr6:34000029    C/T
rs374728385 chr6:34000032    C/A
rs374728385 chr6:34000032    C/G
rs747378297 chr6:34000028    C/T
rs772691699 chr6:34000033    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SAMD14
chr17:48204889(-) A-I      intronic
chr17:48204878(-) A-I      intronic
chr17:48204843(-) A-I      intronic
chr17:48204825(-) A-I      intronic
chr17:48204722(-) A-I      intronic
chr17:48204352(-) A-I      intronic
chr17:48204221(-) A-I      intronic
chr17:48204220(-) A-I      intronic
chr17:48204219(-) A-I      intronic
chr17:48203754(-) A-I      intronic
chr17:48203780(-) A-I      intronic
chr17:48203801(-) A-I      intronic
chr17:48203807(-) A-I      intronic
chr17:48204688(-) A-I      intronic
chr17:48204882(-) A-I      intronic
chr17:48204710(-) A-I      intronic
chr17:48204082(-) A-I      intronic
chr17:48204809(-) A-I      intronic
chr17:48204800(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SAMD14
chr17:48204082(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SAMD14
chr17:48187508-48187509(-) m6A 3'UTR       24981863
chr17:48187559-48187560(-) m6A 3'UTR       24981863
chr17:48187577-48187578(-) m6A 3'UTR       24981863
chr17:48188128-48188129(-) m6A 3'UTR       24284625
chr17:48188159-48188160(-) m6A 3'UTR       24284625
chr17:48188200-48188201(-) m6A 3'UTR       24284625
chr17:48188297-48188298(-) m6A 3'UTR       24284625
chr17:48188356-48188357(-) m6A 3'UTR       24284625
chr17:48188569-48188570(-) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr17:48188612-48188613(-) m6A 3'UTR       24284625//25456834//24981863
chr17:48188639-48188640(-) m6A 3'UTR       24284625//25456834//24981863
chr17:48190178-48190179(-) m6A 3'UTR//exon       27773536
chr17:48191704-48191705(-) m6A exon//intron       -
chr17:48191745-48191746(-) m6A CDS//exon//intron       -
chr17:48193486-48193487(-) m6A exon//intron       -
chr17:48207055-48207056(-) m6A 5'UTR//exon       25456834
chr17:48207106-48207107(-) m6A 5'UTR//exon       25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1275
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
Mitochondrion HeLa cells     27396686
Mitochondrion HeLa cells     27563705
Mitochondrion Cell line (HeLa)     21695135
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleolus HeLa cells     23940654
SAMD14
Cytosol HeLa-S3 cells     -
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-1275
Gemcitabine 60750 Drug interaction    RC00007825
Vincristine 5978 Drug interaction    RC00007823
Eloxatine 5310940 Drug interaction    RC00007826
Paclitaxel 36314 Drug interaction    RC00007824
5-Fluorouracil 3385 Drug interaction    RC00007822
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007821
Marine fungal metabolite 1386A - Drug interaction    RC00007827
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-1275
l-685,458       5479543

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1275
Interactor2: SAMD14

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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