Detail Information

Basic Information:


  VIRBase ID:  

HHID00099001

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1275:           ZBED3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1275 ZBED3
miRBase
Accession/Entrez ID		 MIMAT0005929 84327
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1275
rs372458638 chr6:34000019    A/AAAACC
rs377188203 chr6:34000023    C/T
rs557928121 chr6:34000019    A/T
rs758811783 chr6:34000022    G/A
rs761034364 chr6:34000017    AGAC/A
rs370361021 chr6:34000029    C/A
rs370361021 chr6:34000029    C/T
rs374728385 chr6:34000032    C/A
rs374728385 chr6:34000032    C/G
rs747378297 chr6:34000028    C/T
rs772691699 chr6:34000033    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZBED3
chr5:76377456(-) A-I      intronic
chr5:76377357(-) A-I      intronic
chr5:76378084(-) A-I      intronic
chr5:76377983(-) A-I      intronic
chr5:76377980(-) A-I      intronic
chr5:76377935(-) A-I      intronic
chr5:76377355(-) A-I      intronic
chr5:76377323(-) A-I      intronic
chr5:76377307(-) A-I      intronic
chr5:76377313(-) A-I      intronic
chr5:76377343(-) A-I      intronic
chr5:76377344(-) A-I      intronic
chr5:76378023(-) A-I      intronic
chr5:76378045(-) A-I      intronic
chr5:76377260(-) A-I      intronic
chr5:76377339(-) A-I      intronic
chr5:76378058(-) A-I      intronic
chr5:76377167(-) A-I      intronic
chr5:76377425(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ZBED3
chr5:76377412(-) A-G intron -    22484847
chr5:76378053(-) A-G intron -    22484847
chr5:76378058(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZBED3
chr5:76369314-76369315(-) m6A 3'UTR       27773535
chr5:76369346-76369347(-) m6A 3'UTR       27773535
chr5:76369356-76369357(-) m6A 3'UTR       27773535
chr5:76369454-76369455(-) m6A 3'UTR       27773535
chr5:76369739-76369740(-) m6A 3'UTR       27773535
chr5:76369791-76369792(-) m6A 3'UTR       27773535
chr5:76369824-76369825(-) m6A 3'UTR       27773535
chr5:76369845-76369846(-) m6A 3'UTR       24284625//27773535
chr5:76369921-76369922(-) m6A 3'UTR       24284625//24981863//27773535
chr5:76369941-76369942(-) m6A 3'UTR       24284625//24981863//27773535
chr5:76370237-76370238(-) m6A 3'UTR       27773535
chr5:76370616-76370617(-) m6A 3'UTR       27773535
chr5:76370691-76370692(-) m6A 3'UTR       27773535
chr5:76370915-76370916(-) m6A 3'UTR       27773535
chr5:76370962-76370963(-) m6A 3'UTR       27773535
chr5:76371200-76371201(-) m6A 3'UTR       27773535
chr5:76371280-76371281(-) m6A 3'UTR       24981863//27773535
chr5:76371328-76371329(-) m6A 3'UTR       24981863//27773535
chr5:76371990-76371991(-) m6A 3'UTR       27773535
chr5:76372248-76372249(-) m6A 3'UTR       27773535
chr5:76372310-76372311(-) m6A 3'UTR       24284625//27773535
chr5:76372430-76372431(-) m6A 3'UTR       24284625//24981863//27773535
chr5:76372605-76372606(-) m6A 3'UTR       24284625//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372648-76372649(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372654-76372655(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372687-76372688(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372693-76372694(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372721-76372722(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372801-76372802(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372807-76372808(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372926-76372927(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr5:76372937-76372938(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr5:76372971-76372972(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76373151-76373152(-) m6A CDS       24209618//25456834//24981863//27371828//27773536//22575960
chr5:76373301-76373302(-) m6A CDS       24981863//27371828//27773536//22575960
chr5:76373447-76373448(-) m6A CDS       24209618//27371828//27773536
chr5:76373619-76373620(-) m6A CDS       24209618//24981863//27371828//27773536//22575960
chr5:76373671-76373672(-) m6A CDS       24284625//24981863//27371828//27773536//22575960
chr5:76374459-76374460(-) m6A 5'UTR//intron       24284625//27773535//22575960
chr5:76374479-76374480(-) m6A 5'UTR//intron       24284625//27773535
chr5:76374531-76374532(-) m6A 5'UTR//intron       24284625
chr5:76374876-76374877(-) m6A exon//intron       24284625
chr5:76376340-76376341(-) m6A intron       22575960
chr5:76376389-76376390(-) m6A intron       22575960
chr5:76382980-76382981(-) m6A 5'UTR//exon       24284625//25456834
chr5:76383024-76383025(-) m6A 5'UTR//exon       24284625//25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1275
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
Mitochondrion HeLa cells     27396686
Mitochondrion HeLa cells     27563705
Mitochondrion Cell line (HeLa)     21695135
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleolus HeLa cells     23940654
ZBED3
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-1275
Gemcitabine 60750 Drug interaction    RC00007825
Vincristine 5978 Drug interaction    RC00007823
Eloxatine 5310940 Drug interaction    RC00007826
Paclitaxel 36314 Drug interaction    RC00007824
5-Fluorouracil 3385 Drug interaction    RC00007822
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007821
Marine fungal metabolite 1386A - Drug interaction    RC00007827
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-1275
l-685,458       5479543

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1275
Interactor2: ZBED3

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

Starting a new search, please wait ...