Basic Information:

  VIRBase ID:  

HHID00099000

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1275:  MIMAT0005929          MYO15B:  NM_001309242     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1275	MYO15B
miRBase Accession/Entrez ID	MIMAT0005929	80022
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	MYO15BP

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1275	rs372458638 chr6:34000019    A/AAAACC rs377188203 chr6:34000023    C/T rs557928121 chr6:34000019    A/T rs758811783 chr6:34000022    G/A rs761034364 chr6:34000017    AGAC/A rs370361021 chr6:34000029    C/A rs370361021 chr6:34000029    C/T rs374728385 chr6:34000032    C/A rs374728385 chr6:34000032    C/G rs747378297 chr6:34000028    C/T rs772691699 chr6:34000033    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MYO15B	chr17:73594480(+) A-I      intronic chr17:73604726(+) A-I      intronic chr17:73604730(+) A-I      intronic chr17:73593934(+) A-I      intronic chr17:73594443(+) A-I      intronic chr17:73594448(+) A-I      intronic chr17:73594471(+) A-I      intronic chr17:73596760(+) A-I      intronic chr17:73597126(+) A-I      intronic chr17:73604269(+) A-I      intronic chr17:73604595(+) A-I      intronic chr17:73604628(+) A-I      intronic chr17:73604698(+) A-I      intronic chr17:73593922(+) A-I      intronic chr17:73593734(+) A-I      intronic chr17:73593834(+) A-I      intronic chr17:73593838(+) A-I      intronic chr17:73593839(+) A-I      intronic chr17:73593886(+) A-I      intronic chr17:73594435(+) A-I      intronic chr17:73594474(+) A-I      intronic chr17:73594512(+) A-I      intronic chr17:73594525(+) A-I      intronic chr17:73594624(+) A-I      intronic chr17:73595241(+) A-I      intronic chr17:73595481(+) A-I      intronic chr17:73595482(+) A-I      intronic chr17:73595497(+) A-I      intronic chr17:73595609(+) A-I      intronic chr17:73595763(+) A-I      intronic chr17:73596290(+) A-I      intronic chr17:73605365(+) A-I      intronic chr17:73595963(+) A-I      intronic chr17:73604739(+) A-I      intronic chr17:73596806(+) A-I      intronic chr17:73589250(+) A-I      intronic chr17:73604607(+) A-I      intronic chr17:73601533(+) A-I      intronic chr17:73602513(+) A-I      intronic chr17:73589503(+) A-I      intronic chr17:73602435(+) A-I      intronic chr17:73596598(+) A-I      intronic chr17:73597280(+) A-I      intronic chr17:73597246(+) A-I      intronic chr17:73596237(+) A-I      intronic chr17:73593729(+) A-I      intronic chr17:73605386(+) A-I      intronic chr17:73595823(+) A-I      intronic chr17:73604709(+) A-I      intronic chr17:73597342(+) A-I      intronic chr17:73604695(+) A-I      intronic chr17:73603816(+) A-I      intronic chr17:73604602(+) A-I      intronic chr17:73604756(+) A-I      intronic chr17:73619385(+) A-I      intronic chr17:73596560(+) A-I      intronic chr17:73604658(+) A-I      intronic chr17:73594274(+) A-I      intronic chr17:73593874(+) A-I      intronic chr17:73594294(+) A-I      intronic chr17:73604400(+) A-I      intronic chr17:73595436(+) A-I      intronic chr17:73596903(+) A-I      intronic chr17:73594538(+) A-I      intronic chr17:73593811(+) A-I      intronic chr17:73604740(+) A-I      intronic chr17:73604601(+) A-I      intronic chr17:73593850(+) A-I      intronic chr17:73593841(+) A-I      intronic chr17:73594261(+) A-I      intronic chr17:73595696(+) A-I      intronic chr17:73594472(+) A-I      intronic chr17:73595640(+) A-I      intronic chr17:73605221(+) A-I      intronic chr17:73595495(+) A-I      intronic chr17:73604663(+) A-I      intronic chr17:73604615(+) A-I      intronic chr17:73595485(+) A-I      intronic chr17:73594498(+) A-I      intronic chr17:73594548(+) A-I      intronic chr17:73589980(+) A-I      intronic chr17:73595732(+) A-I      intronic chr17:73597150(+) A-I      intronic chr17:73593876(+) A-I      intronic chr17:73590184(+) A-I      intronic chr17:73593847(+) A-I      intronic chr17:73597258(+) A-I      intronic chr17:73595613(+) A-I      intronic chr17:73597169(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MYO15B	chr17:73601345(+) T-C intron -    21725310

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MYO15B	chr17:73584321-73584322(+) m6A CDS       - chr17:73584583-73584584(+) m6A CDS       25456834 chr17:73584619-73584620(+) m6A CDS       25456834 chr17:73584627-73584628(+) m6A CDS       25456834 chr17:73584700-73584701(+) m6A CDS       25456834 chr17:73584717-73584718(+) m6A CDS       25456834 chr17:73584723-73584724(+) m6A CDS       25456834 chr17:73584766-73584767(+) m6A CDS       25456834 chr17:73584853-73584854(+) m6A CDS       25456834 chr17:73584876-73584877(+) m6A CDS       25456834 chr17:73584881-73584882(+) m6A CDS       25456834 chr17:73584918-73584919(+) m6A CDS       25456834 chr17:73584928-73584929(+) m6A CDS       25456834 chr17:73584949-73584950(+) m6A CDS       25456834 chr17:73585008-73585009(+) m6A CDS       25456834//27371828 chr17:73585367-73585368(+) m6A CDS       25456834 chr17:73585573-73585574(+) m6A CDS       25456834 chr17:73585749-73585750(+) m6A CDS       - chr17:73586019-73586020(+) m6A CDS       - chr17:73586121-73586122(+) m6A CDS       25456834 chr17:73586143-73586144(+) m6A CDS       25456834 chr17:73586180-73586181(+) m6A CDS       25456834 chr17:73586215-73586216(+) m6A CDS       25456834 chr17:73586299-73586300(+) m6A CDS       25456834 chr17:73586308-73586309(+) m6A CDS       25456834 chr17:73586410-73586411(+) m6A CDS//intron       - chr17:73606333-73606334(+) m6A 3'UTR//CDS       24981863 chr17:73608050-73608051(+) m6A 3'UTR//CDS//exon       - chr17:73608880-73608881(+) m6A 3'UTR//CDS//exon//intron       - chr17:73608939-73608940(+) m6A 3'UTR//CDS//exon       - chr17:73608960-73608961(+) m6A 3'UTR//CDS//exon       - chr17:73609817-73609818(+) m6A 3'UTR//CDS       - chr17:73610341-73610342(+) m6A 3'UTR//CDS       - chr17:73610368-73610369(+) m6A 3'UTR//CDS       - chr17:73610382-73610383(+) m6A 3'UTR//CDS       - chr17:73610389-73610390(+) m6A 3'UTR//CDS       - chr17:73610398-73610399(+) m6A 3'UTR//CDS       - chr17:73612152-73612153(+) m6A 3'UTR//CDS//exon//intron       - chr17:73612171-73612172(+) m6A 3'UTR//CDS//exon//intron       - chr17:73612210-73612211(+) m6A 3'UTR//CDS//exon//intron       - chr17:73612517-73612518(+) m6A CDS//exon//intron       25456834//24981863 chr17:73612698-73612699(+) m6A CDS//exon//intron       25456834//24981863 chr17:73612743-73612744(+) m6A CDS//exon//intron       25456834 chr17:73612762-73612763(+) m6A CDS//exon//intron       25456834 chr17:73613279-73613280(+) m6A 3'UTR//CDS//exon       - chr17:73613354-73613355(+) m6A 3'UTR//CDS//exon       - chr17:73613362-73613363(+) m6A 3'UTR//CDS//exon       - chr17:73616398-73616399(+) m6A 3'UTR//CDS//exon       - chr17:73616580-73616581(+) m6A 3'UTR//CDS//exon//intron       - chr17:73616682-73616683(+) m6A 3'UTR//CDS//exon//intron       25456834//24981863 chr17:73616702-73616703(+) m6A 3'UTR//CDS//exon//intron       25456834//24981863 chr17:73616736-73616737(+) m6A 3'UTR//CDS//exon//intron       25456834//24981863 chr17:73616762-73616763(+) m6A 3'UTR//exon//intron       25456834//24981863 chr17:73616812-73616813(+) m6A 3'UTR//exon//intron       25456834//24981863//27371828 chr17:73616885-73616886(+) m6A 3'UTR//exon//intron       25456834//24981863//27371828 chr17:73616980-73616981(+) m6A 3'UTR//exon//intron       27371828 chr17:73617697-73617698(+) m6A exon//intron       27371828 chr17:73617786-73617787(+) m6A exon//intron       27371828 chr17:73620904-73620905(+) m6A 3'UTR//CDS       - chr17:73620945-73620946(+) m6A 3'UTR//CDS       - chr17:73621212-73621213(+) m6A 3'UTR//CDS       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1275	Exosome Breast cancer cell line (MCF-7)     20976003 Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     - Mitochondrion HeLa cells     27396686 Mitochondrion HeLa cells     27563705 Mitochondrion Cell line (HeLa)     21695135 Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleolus HeLa cells     23940654
	MYO15B	Exosome Blood     - Nucleolus K562 cells     - Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-1275	Gemcitabine 60750 Drug interaction    RC00007825 Vincristine 5978 Drug interaction    RC00007823 Eloxatine 5310940 Drug interaction    RC00007826 Paclitaxel 36314 Drug interaction    RC00007824 5-Fluorouracil 3385 Drug interaction    RC00007822 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007821 Marine fungal metabolite 1386A - Drug interaction    RC00007827

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsa-miR-1275	l-685,458       5479543

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1275
Interactor2: MYO15B

Evidence Support:

Weak-Evidence	Illumina sequencing
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32223537	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Calu-3 cells	Interactor2 expression	Upregulation
Description	The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.