Basic Information:

  VIRBase ID:  

HHID00098984

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1275:  MIMAT0005929          FGFR1:  NM_001174066     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1275	FGFR1
miRBase Accession/Entrez ID	MIMAT0005929	2260
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	bFGF-R-1//BFGFR//CD331//CEK//ECCL//FGFBR//FGFR-1//FLG//FLT-2//FLT2//HBGFR//HH2//HRTFDS//KAL2//N-SAM//OGD

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1275	rs372458638 chr6:34000019    A/AAAACC rs377188203 chr6:34000023    C/T rs557928121 chr6:34000019    A/T rs758811783 chr6:34000022    G/A rs761034364 chr6:34000017    AGAC/A rs370361021 chr6:34000029    C/A rs370361021 chr6:34000029    C/T rs374728385 chr6:34000032    C/A rs374728385 chr6:34000032    C/G rs747378297 chr6:34000028    C/T rs772691699 chr6:34000033    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FGFR1	chr8:38290143(-) A-I      intronic chr8:38290163(-) A-I      intronic chr8:38294577(-) A-I      intronic chr8:38294586(-) A-I      intronic chr8:38301179(-) A-I      intronic chr8:38295985(-) A-I      intronic chr8:38295979(-) A-I      intronic chr8:38295974(-) A-I      intronic chr8:38301431(-) A-I      intronic chr8:38310395(-) A-I      intronic chr8:38305232(-) A-I      intronic chr8:38295834(-) A-I      intronic chr8:38294630(-) A-I      intronic chr8:38294617(-) A-I      intronic chr8:38294616(-) A-I      intronic chr8:38294602(-) A-I      intronic chr8:38294599(-) A-I      intronic chr8:38294594(-) A-I      intronic chr8:38293883(-) A-I      intronic chr8:38293663(-) A-I      intronic chr8:38291801(-) A-I      intronic chr8:38291010(-) A-I      intronic chr8:38291006(-) A-I      intronic chr8:38290944(-) A-I      intronic chr8:38290897(-) A-I      intronic chr8:38290804(-) A-I      intronic chr8:38290785(-) A-I      intronic chr8:38290701(-) A-I      intronic chr8:38290593(-) A-I      intronic chr8:38290169(-) A-I      intronic chr8:38290068(-) A-I      intronic chr8:38290055(-) A-I      intronic chr8:38290028(-) A-I      intronic chr8:38290027(-) A-I      intronic chr8:38284961(-) A-I      intronic chr8:38284911(-) A-I      intronic chr8:38310433(-) A-I      intronic chr8:38290100(-) A-I      intronic chr8:38290098(-) A-I      intronic chr8:38290087(-) A-I      intronic chr8:38303814(-) A-I      intronic chr8:38303822(-) A-I      intronic chr8:38305912(-) A-I      intronic chr8:38311177(-) A-I      intronic chr8:38311328(-) A-I      intronic chr8:38312977(-) A-I      intronic chr8:38304098(-) A-I      intronic chr8:38304222(-) A-I      intronic chr8:38312999(-) A-I      intronic chr8:38313038(-) A-I      intronic chr8:38317535(-) A-I      intronic chr8:38306301(-) A-I      intronic chr8:38306351(-) A-I      intronic chr8:38302128(-) A-I      intronic chr8:38305103(-) A-I      intronic chr8:38317618(-) A-I      intronic chr8:38320587(-) A-I      intronic chr8:38320394(-) A-I      intronic chr8:38320389(-) A-I      intronic chr8:38320373(-) A-I      intronic chr8:38318905(-) A-I      intronic chr8:38320372(-) A-I      intronic chr8:38320368(-) A-I      intronic chr8:38319789(-) A-I      intronic chr8:38305111(-) A-I      intronic chr8:38305179(-) A-I      intronic chr8:38310480(-) A-I      intronic chr8:38309969(-) A-I      intronic chr8:38306364(-) A-I      intronic chr8:38306373(-) A-I      intronic chr8:38306410(-) A-I      intronic chr8:38306520(-) A-I      intronic chr8:38306538(-) A-I      intronic chr8:38306558(-) A-I      intronic chr8:38293675(-) A-I      intronic chr8:38293676(-) A-I      intronic chr8:38293710(-) A-I      intronic chr8:38293713(-) A-I      intronic chr8:38293765(-) A-I      intronic chr8:38301106(-) A-I      intronic chr8:38301108(-) A-I      intronic chr8:38301109(-) A-I      intronic chr8:38301185(-) A-I      intronic chr8:38301449(-) A-I      intronic chr8:38306238(-) A-I      intronic chr8:38306589(-) A-I      intronic chr8:38294591(-) A-I      intronic chr8:38294622(-) A-I      intronic chr8:38294635(-) A-I      intronic chr8:38311176(-) A-I      intronic chr8:38310021(-) A-I      intronic chr8:38290113(-) A-I      intronic chr8:38290110(-) A-I      intronic chr8:38290109(-) A-I      intronic chr8:38320310(-) A-I      intronic chr8:38320289(-) A-I      intronic chr8:38320254(-) A-I      intronic chr8:38318940(-) A-I      intronic chr8:38318929(-) A-I      intronic chr8:38318918(-) A-I      intronic chr8:38318910(-) A-I      intronic chr8:38302182(-) A-I      intronic chr8:38302129(-) A-I      intronic chr8:38290108(-) A-I      intronic chr8:38290107(-) A-I      intronic chr8:38290106(-) A-I      intronic chr8:38290104(-) A-I      intronic chr8:38303724(-) A-I      intronic chr8:38301972(-) A-I      intronic chr8:38310027(-) A-I      intronic chr8:38310076(-) A-I      intronic chr8:38310251(-) A-I      intronic chr8:38310276(-) A-I      intronic chr8:38310330(-) A-I      intronic chr8:38310386(-) A-I      intronic chr8:38302000(-) A-I      intronic chr8:38302039(-) A-I      intronic chr8:38302106(-) A-I      intronic chr8:38269756(-) A-I      3'UTR chr8:38306504(-) A-I      intronic chr8:38310222(-) A-I      intronic chr8:38291800(-) A-I      intronic chr8:38290165(-) A-I      intronic chr8:38293648(-) A-I      intronic chr8:38320286(-) A-I      intronic chr8:38310031(-) A-I      intronic chr8:38312910(-) A-I      intronic chr8:38306316(-) A-I      intronic chr8:38310029(-) A-I      intronic chr8:38320298(-) A-I      intronic chr8:38310313(-) A-I      intronic chr8:38303980(-) A-I      intronic chr8:38306397(-) A-I      intronic chr8:38291120(-) A-I      intronic chr8:38291022(-) A-I      intronic chr8:38294537(-) A-I      intronic chr8:38320236(-) A-I      intronic chr8:38311404(-) A-I      intronic chr8:38304046(-) A-I      intronic chr8:38293771(-) A-I      intronic chr8:38311190(-) A-I      intronic chr8:38300959(-) A-I      intronic chr8:38317538(-) A-I      intronic chr8:38305938(-) A-I      intronic chr8:38318883(-) A-I      intronic chr8:38320260(-) A-I      intronic chr8:38285030(-) A-I      intronic chr8:38311255(-) A-I      intronic chr8:38320301(-) A-I      intronic chr8:38310077(-) A-I      intronic chr8:38303826(-) A-I      intronic chr8:38312740(-) A-I      intronic chr8:38310113(-) A-I      intronic chr8:38320167(-) A-I      intronic chr8:38314378(-) A-I      intronic chr8:38293769(-) A-I      intronic chr8:38290967(-) A-I      intronic chr8:38311334(-) A-I      intronic chr8:38305926(-) A-I      intronic chr8:38290099(-) A-I      intronic chr8:38290683(-) A-I      intronic chr8:38290157(-) A-I      intronic chr8:38320697(-) A-I      intronic chr8:38293727(-) A-I      intronic chr8:38319028(-) A-I      intronic chr8:38319859(-) A-I      intronic chr8:38269767(-) A-I      3'UTR chr8:38269706(-) A-I      3'UTR chr8:38269763(-) A-I      3'UTR chr8:38269667(-) A-I      3'UTR chr8:38318888(-) A-I      intronic chr8:38317615(-) A-I      intronic chr8:38318925(-) A-I      intronic chr8:38293745(-) A-I      intronic chr8:38321587(-) A-I      intronic chr8:38293761(-) A-I      intronic chr8:38306533(-) A-I      intronic chr8:38311262(-) A-I      intronic chr8:38294580(-) A-I      intronic chr8:38319099(-) A-I      intronic chr8:38306498(-) A-I      intronic chr8:38320162(-) A-I      intronic chr8:38317695(-) A-I      intronic chr8:38310373(-) A-I      intronic chr8:38312596(-) A-I      intronic chr8:38304136(-) A-I      intronic chr8:38304047(-) A-I      intronic chr8:38302156(-) A-I      intronic chr8:38304120(-) A-I      intronic chr8:38310310(-) A-I      intronic chr8:38295809(-) A-I      intronic chr8:38309951(-) A-I      intronic chr8:38294483(-) A-I      intronic chr8:38306537(-) A-I      intronic chr8:38301069(-) A-I      intronic chr8:38301067(-) A-I      intronic chr8:38318961(-) A-I      intronic chr8:38293812(-) A-I      intronic chr8:38305900(-) A-I      intronic chr8:38320239(-) A-I      intronic chr8:38300943(-) A-I      intronic chr8:38290902(-) A-I      intronic chr8:38304216(-) A-I      intronic chr8:38319856(-) A-I      intronic chr8:38320696(-) A-I      intronic chr8:38300986(-) A-I      intronic chr8:38305922(-) A-I      intronic chr8:38291016(-) A-I      intronic chr8:38319910(-) A-I      intronic chr8:38320291(-) A-I      intronic chr8:38290896(-) A-I      intronic chr8:38305880(-) A-I      intronic chr8:38317624(-) A-I      intronic chr8:38304199(-) A-I      intronic chr8:38317687(-) A-I      intronic chr8:38304206(-) A-I      intronic chr8:38306256(-) A-I      intronic chr8:38303301(-) A-I      intronic chr8:38293811(-) A-I      intronic chr8:38311506(-) A-I      intronic chr8:38293786(-) A-I      intronic chr8:38290590(-) A-I      intronic chr8:38319767(-) A-I      intronic chr8:38291046(-) A-I      intronic chr8:38310153(-) A-I      intronic chr8:38320688(-) A-I      intronic chr8:38312669(-) A-I      intronic chr8:38314297(-) A-I      intronic chr8:38310140(-) A-I      intronic chr8:38301139(-) A-I      intronic chr8:38306426(-) A-I      intronic chr8:38311175(-) A-I      intronic chr8:38311508(-) A-I      intronic chr8:38311202(-) A-I      intronic chr8:38317458(-) A-I      intronic chr8:38302047(-) A-I      intronic chr8:38311278(-) A-I      intronic chr8:38290095(-) A-I      intronic chr8:38312973(-) A-I      intronic chr8:38309988(-) A-I      intronic chr8:38312667(-) A-I      intronic chr8:38301519(-) A-I      intronic chr8:38290152(-) A-I      intronic chr8:38305858(-) A-I      intronic chr8:38305057(-) A-I      intronic chr8:38310229(-) A-I      intronic chr8:38300930(-) A-I      intronic chr8:38302004(-) A-I      intronic chr8:38293721(-) A-I      intronic chr8:38291031(-) A-I      intronic chr8:38284890(-) A-I      intronic chr8:38306390(-) A-I      intronic chr8:38295978(-) A-I      intronic chr8:38318950(-) A-I      intronic chr8:38309905(-) A-I      intronic chr8:38303804(-) A-I      intronic chr8:38290757(-) A-I      intronic chr8:38311288(-) A-I      intronic chr8:38294631(-) A-I      intronic chr8:38310486(-) A-I      intronic chr8:38306307(-) A-I      intronic chr8:38320675(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FGFR1	chr8:38303278(-) A-I intron -    15342557 chr8:38303290(-) A-I intron -    15342557 chr8:38303291(-) A-I intron -    15342557 chr8:38303301(-) A-I intron -    15342557 chr8:38303826(-) A-I intron -    15342557 chr8:38303980(-) A-I intron -    15342557 chr8:38304046(-) A-I intron -    15342557 chr8:38304047(-) A-I intron -    15342557 chr8:38304068(-) A-I intron -    15342557 chr8:38304120(-) A-I intron -    15342557 chr8:38304169(-) A-I intron -    15342557 chr8:38304199(-) A-I intron -    15342557 chr8:38304200(-) A-I intron -    15342557 chr8:38304206(-) A-I intron -    15342557 chr8:38304216(-) A-I intron -    15342557 chr8:38269706(-) A-G exon 3'UTR    22484847 chr8:38290095(-) A-G intron -    22484847 chr8:38290152(-) A-G intron -    22484847 chr8:38290157(-) A-G intron -    22484847 chr8:38290165(-) A-G intron -    22484847 chr8:38291061(-) A-G intron -    22484847 chr8:38292660(-) A-G intron -    22484847 chr8:38292661(-) A-G intron -    22484847 chr8:38300998(-) A-G intron -    22484847 chr8:38301067(-) A-G intron -    22484847 chr8:38301069(-) A-G intron -    22484847 chr8:38305922(-) A-G intron -    22484847 chr8:38306307(-) A-G intron -    22484847 chr8:38306397(-) A-G intron -    22484847 chr8:38309938(-) A-G intron -    22484847 chr8:38309951(-) A-G intron -    22484847 chr8:38310007(-) A-G intron -    22484847 chr8:38310029(-) A-G intron -    22484847 chr8:38310031(-) A-G intron -    22484847 chr8:38310080(-) A-G intron -    22484847 chr8:38310140(-) A-G intron -    22484847 chr8:38310373(-) A-G intron -    22484847 chr8:38310387(-) A-G intron -    22484847 chr8:38311255(-) A-G intron -    22484847 chr8:38311327(-) A-G intron -    22484847 chr8:38311334(-) A-G intron -    22484847 chr8:38317538(-) A-G intron -    22484847 chr8:38317615(-) A-G intron -    22484847 chr8:38317638(-) A-G intron -    22484847 chr8:38318888(-) A-G intron -    22484847 chr8:38319856(-) A-G intron -    22484847 chr8:38320688(-) A-G intron -    22484847 chr8:38320696(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FGFR1	chr8:38269197-38269198(-) m6A 3'UTR       - chr8:38269340-38269341(-) m6A 3'UTR       26404942 chr8:38269381-38269382(-) m6A 3'UTR       24981863//26404942 chr8:38269396-38269397(-) m6A 3'UTR       24981863//26404942 chr8:38269492-38269493(-) m6A 3'UTR       24981863//26404942 chr8:38269551-38269552(-) m6A 3'UTR       24981863//26404942 chr8:38269557-38269558(-) m6A 3'UTR       24981863//26404942//22608085 chr8:38269563-38269564(-) m6A 3'UTR       24981863//26404942//22608085 chr8:38269586-38269587(-) m6A 3'UTR       24981863//22608085 chr8:38269598-38269599(-) m6A 3'UTR       24981863//22608085 chr8:38269823-38269824(-) m6A 3'UTR//exon       24209618 chr8:38270829-38270830(-) m6A 3'UTR//exon//intron       24981863 chr8:38270888-38270889(-) m6A 3'UTR//exon//intron       24981863 chr8:38271120-38271121(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//28052920//27371828//22608085 chr8:38271160-38271161(-) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27371828//22608085 chr8:38271293-38271294(-) m6A 3'UTR//CDS//exon//intron       27773535 chr8:38271311-38271312(-) m6A 3'UTR//CDS//exon//intron       27773535 chr8:38272304-38272305(-) m6A 3'UTR//CDS//exon       24981863 chr8:38272333-38272334(-) m6A 3'UTR//CDS//exon       24981863 chr8:38272351-38272352(-) m6A 3'UTR//CDS//exon       24981863 chr8:38272372-38272373(-) m6A 3'UTR//CDS//exon       24981863 chr8:38272405-38272406(-) m6A 3'UTR//CDS//exon       24981863 chr8:38275431-38275432(-) m6A 3'UTR//CDS//exon       26404942 chr8:38275437-38275438(-) m6A 3'UTR//CDS//exon       26404942 chr8:38281822-38281823(-) m6A exon//intron       - chr8:38281860-38281861(-) m6A exon//intron       - chr8:38282054-38282055(-) m6A 3'UTR//CDS//exon//intron       26404942 chr8:38282166-38282167(-) m6A 3'UTR//CDS//exon//intron       26404942//27371828//27773536 chr8:38283731-38283732(-) m6A 3'UTR//CDS//exon//intron       27371828 chr8:38285980-38285981(-) m6A exon//intron       27773535 chr8:38287288-38287289(-) m6A CDS//exon//intron       24284625 chr8:38292035-38292036(-) m6A intron       25456834 chr8:38292083-38292084(-) m6A intron       25456834//24981863 chr8:38292105-38292106(-) m6A intron       25456834//24981863 chr8:38292705-38292706(-) m6A intron       24981863 chr8:38292714-38292715(-) m6A intron       24981863 chr8:38292720-38292721(-) m6A intron       24981863 chr8:38325515-38325516(-) m6A 5'UTR//exon       27371828//27773536 chr8:38325531-38325532(-) m6A 5'UTR//exon       27371828//27773536 chr8:38325600-38325601(-) m6A 5'UTR//exon       24209618//27371828//27773536 chr8:38325606-38325607(-) m6A 5'UTR//exon       24209618//27371828//27773536 chr8:38325755-38325756(-) m6A 5'UTR//exon       25456834//27371828//27773536 chr8:38325921-38325922(-) m6A 5'UTR//exon       24209618//25456834//24981863//26404942//27371828//27773536 chr8:38325929-38325930(-) m6A 5'UTR//exon       24209618//25456834//24981863//26404942//27371828//27773536 chr8:38326001-38326002(-) m6A 5'UTR//exon       24209618//25456834//24981863//27371828//27773536 chr8:38326007-38326008(-) m6A 5'UTR//exon       24209618//25456834//24981863//27371828//27773536 chr8:38326048-38326049(-) m6A 5'UTR//exon       24209618//25456834//24981863//27371828//27773536 chr8:38326199-38326200(-) m6A 5'UTR       25456834//24981863//27371828 chr8:38326246-38326247(-) m6A 5'UTR       25456834//27371828 chr8:38326289-38326290(-) m6A 5'UTR       25456834//27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1275	Exosome Breast cancer cell line (MCF-7)     20976003 Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     - Mitochondrion HeLa cells     27396686 Mitochondrion HeLa cells     27563705 Mitochondrion Cell line (HeLa)     21695135 Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleolus HeLa cells     23940654
	FGFR1	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-1275	Gemcitabine 60750 Drug interaction    RC00007825 Vincristine 5978 Drug interaction    RC00007823 Eloxatine 5310940 Drug interaction    RC00007826 Paclitaxel 36314 Drug interaction    RC00007824 5-Fluorouracil 3385 Drug interaction    RC00007822 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007821 Marine fungal metabolite 1386A - Drug interaction    RC00007827

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsa-miR-1275	l-685,458       5479543

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1275
Interactor2: FGFR1

Evidence Support:

Weak-Evidence	Illumina sequencing
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32223537	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Calu-3 cells	Interactor2 expression	Upregulation
Description	The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.