Detail Information

Basic Information:


  VIRBase ID:  

HHID00098964

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-26a-1-3p:           PSD3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-26a-1-3p PSD3
miRBase
Accession/Entrez ID		 MIMAT0004499 23362
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - EFA6D//EFA6R//HCA67

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-26a-1-3p
rs182070256 chr3:37969473    G/A
rs771522629 chr3:37969472    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PSD3
chr8:18523693(-) A-I      intronic
chr8:18476283(-) A-I      intronic
chr8:18472406(-) A-I      intronic
chr8:18472392(-) A-I      intronic
chr8:18472379(-) A-I      intronic
chr8:18472362(-) A-I      intronic
chr8:18472359(-) A-I      intronic
chr8:18472349(-) A-I      intronic
chr8:18440520(-) A-I      intronic
chr8:18440516(-) A-I      intronic
chr8:18440447(-) A-I      intronic
chr8:18420242(-) A-I      intronic
chr8:18401016(-) A-I      intronic
chr8:18401006(-) A-I      intronic
chr8:18824734(-) A-I      intronic
chr8:18687610(-) A-I      intronic
chr8:18845317(-) A-I      intronic
chr8:18857824(-) A-I      intronic
chr8:18857837(-) A-I      intronic
chr8:18823814(-) A-I      intronic
chr8:18545497(-) A-I      intronic
chr8:18687563(-) A-I      intronic
chr8:18545461(-) A-I      intronic
chr8:18803281(-) A-I      intronic
chr8:18545457(-) A-I      intronic
chr8:18687556(-) A-I      intronic
chr8:18687703(-) A-I      intronic
chr8:18681682(-) A-I      intronic
chr8:18681670(-) A-I      intronic
chr8:18681661(-) A-I      intronic
chr8:18678487(-) A-I      intronic
chr8:18545455(-) A-I      intronic
chr8:18678484(-) A-I      intronic
chr8:18545451(-) A-I      intronic
chr8:18634691(-) A-I      intronic
chr8:18803274(-) A-I      intronic
chr8:18545447(-) A-I      intronic
chr8:18545438(-) A-I      intronic
chr8:18545416(-) A-I      intronic
chr8:18634621(-) A-I      intronic
chr8:18545410(-) A-I      intronic
chr8:18562946(-) A-I      intronic
chr8:18440938(-) A-I      intronic
chr8:18440937(-) A-I      intronic
chr8:18440934(-) A-I      intronic
chr8:18440914(-) A-I      intronic
chr8:18803268(-) A-I      intronic
chr8:18803265(-) A-I      intronic
chr8:18814850(-) A-I      intronic
chr8:18561944(-) A-I      intronic
chr8:18688969(-) A-I      intronic
chr8:18561940(-) A-I      intronic
chr8:18803865(-) A-I      intronic
chr8:18440460(-) A-I      intronic
chr8:18558677(-) A-I      intronic
chr8:18480659(-) A-I      intronic
chr8:18562964(-) A-I      intronic
chr8:18803415(-) A-I      intronic
chr8:18610661(-) A-I      intronic
chr8:18440853(-) A-I      intronic
chr8:18824842(-) A-I      intronic
chr8:18470042(-) A-I      intronic
chr8:18689251(-) A-I      intronic
chr8:18686525(-) A-I      intronic
chr8:18560261(-) A-I      intronic
chr8:18638202(-) A-I      intronic
chr8:18677359(-) A-I      intronic
chr8:18813417(-) A-I      intronic
chr8:18476274(-) A-I      intronic
chr8:18562989(-) A-I      intronic
chr8:18544924(-) A-I      intronic
chr8:18476362(-) A-I      intronic
chr8:18845213(-) A-I      intronic
chr8:18842622(-) A-I      intronic
chr8:18799387(-) A-I      intronic
chr8:18440761(-) A-I      intronic
chr8:18824869(-) A-I      intronic
chr8:18440704(-) A-I      intronic
chr8:18544854(-) A-I      intronic
chr8:18677358(-) A-I      intronic
chr8:18860841(-) A-I      intronic
chr8:18476355(-) A-I      intronic
chr8:18544907(-) A-I      intronic
chr8:18532484(-) A-I      intronic
chr8:18562897(-) A-I      intronic
chr8:18677227(-) A-I      intronic
chr8:18480690(-) A-I      intronic
chr8:18681479(-) A-I      intronic
chr8:18562965(-) A-I      intronic
chr8:18561930(-) A-I      intronic
chr8:18841312(-) A-I      intronic
chr8:18808750(-) A-I      intronic
chr8:18544932(-) A-I      intronic
chr8:18545882(-) A-I      intronic
chr8:18428567(-) A-I      intronic
chr8:18478012(-) A-I      intronic
chr8:18842608(-) A-I      intronic
chr8:18440856(-) A-I      intronic
chr8:18510289(-) A-I      intronic
chr8:18812816(-) A-I      intronic
chr8:18863119(-) A-I      intronic
chr8:18478048(-) A-I      intronic
chr8:18476910(-) A-I      intronic
chr8:18824859(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PSD3
chr8:18385664-18385665(-) m6A 3'UTR       27773535
chr8:18385872-18385873(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22608085
chr8:18385935-18385936(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085
chr8:18386056-18386057(-) m6A 3'UTR       24284625//24981863
chr8:18386105-18386106(-) m6A 3'UTR       24284625
chr8:18386157-18386158(-) m6A 3'UTR       24284625//24981863
chr8:18386398-18386399(-) m6A 3'UTR       24284625//25456834//24981863//27773535
chr8:18386403-18386404(-) m6A 3'UTR       24284625//25456834//24981863//27773535
chr8:18386465-18386466(-) m6A 3'UTR       25456834//24981863
chr8:18386831-18386832(-) m6A 3'UTR       24981863//27773535
chr8:18386846-18386847(-) m6A 3'UTR       24981863//27773535
chr8:18386889-18386890(-) m6A 3'UTR       24981863//27773535
chr8:18386896-18386897(-) m6A 3'UTR       24981863//27773535
chr8:18386960-18386961(-) m6A 3'UTR       27773535
chr8:18387244-18387245(-) m6A 3'UTR       24981863//27773535
chr8:18387251-18387252(-) m6A 3'UTR       24981863//27773535
chr8:18387339-18387340(-) m6A 3'UTR       24981863
chr8:18393281-18393282(-) m6A 3'UTR//CDS//exon       27773535
chr8:18393352-18393353(-) m6A 3'UTR//CDS//exon       24284625//24981863
chr8:18393384-18393385(-) m6A 3'UTR//CDS//exon       24284625//24981863
chr8:18393464-18393465(-) m6A 3'UTR//CDS//exon       24981863
chr8:18413737-18413738(-) m6A 3'UTR//CDS//exon       -
chr8:18430046-18430047(-) m6A 3'UTR//CDS//exon//intron       27773535
chr8:18725317-18725318(-) m6A CDS       24284625//24981863//27773535//22608085
chr8:18725331-18725332(-) m6A CDS       24284625//24981863//27773535//22608085
chr8:18725430-18725431(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr8:18725468-18725469(-) m6A CDS       24284625//24209618//24981863//27773535//27773536//22608085
chr8:18725478-18725479(-) m6A CDS       24284625//24209618//24981863//27773535//27773536//22608085
chr8:18725510-18725511(-) m6A CDS       24284625//24209618//24981863//27773535//27773536//22608085
chr8:18725537-18725538(-) m6A CDS       24284625//24209618//24981863//27773535//27773536//22608085
chr8:18725569-18725570(-) m6A CDS       24284625//24209618//24981863//27773535//27773536//22608085
chr8:18729144-18729145(-) m6A CDS       24284625//24209618//24981863//27773535//27773536//22608085
chr8:18729155-18729156(-) m6A CDS       24284625//24209618//24981863//27773535//27773536//22608085
chr8:18729163-18729164(-) m6A CDS       24284625//24209618//24981863//27773535//27773536//22608085
chr8:18729183-18729184(-) m6A CDS       24284625//24981863//27773535//27773536//22608085
chr8:18729241-18729242(-) m6A CDS       24284625//24981863//27773535//27773536//22608085
chr8:18729388-18729389(-) m6A CDS       24284625//24209618//24981863//27773536//22608085
chr8:18729403-18729404(-) m6A CDS       24284625//24209618//24981863//27773536//22608085
chr8:18729427-18729428(-) m6A CDS       24284625//24209618//24981863//27773535//27773536//22608085
chr8:18729438-18729439(-) m6A CDS       24284625//24209618//24981863//27773535//27773536//22608085
chr8:18729448-18729449(-) m6A CDS       24284625//24209618//24981863//27773535//27773536//22608085
chr8:18729482-18729483(-) m6A CDS       24284625//24981863//27773535//27773536//22608085
chr8:18729702-18729703(-) m6A CDS       24284625//24981863//27773535//22608085
chr8:18729835-18729836(-) m6A CDS       24284625//24981863//27773535//22608085
chr8:18729852-18729853(-) m6A CDS       24284625//24981863//27773535//22608085
chr8:18729903-18729904(-) m6A CDS       24284625//25456834//24981863//26404942//27773535//22608085
chr8:18729928-18729929(-) m6A CDS       24284625//25456834//24981863//26404942//27773535//22608085
chr8:18729998-18729999(-) m6A CDS       24284625//24981863//26404942//27773535//22608085
chr8:18730043-18730044(-) m6A CDS       24284625//24981863//27773535//22608085
chr8:18730180-18730181(-) m6A 5'UTR//CDS       24284625
chr8:18793645-18793646(-) m6A CDS//exon       -
chr8:18797630-18797631(-) m6A exon//intron       -
chr8:18797642-18797643(-) m6A exon//intron       -
chr8:18797658-18797659(-) m6A exon//intron       -
chr8:18797938-18797939(-) m6A exon//intron       27773536
chr8:18871584-18871585(-) m6A exon//intron       27773536
chr8:18871587-18871588(-) m1A exon//intron       26863196//26863410
chr8:18871600-18871601(-) m6A exon//intron       27773536
chr8:18942092-18942093(-) m6A 5'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-26a-1-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
PSD3
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-26a-1-3p
Interactor2: PSD3

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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