Detail Information

Basic Information:


  VIRBase ID:  

HHID00098951

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:           ZNF597:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-1-3p ZNF597
miRBase
Accession/Entrez ID		 MIMAT0004489 146434
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HIT-4

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-1-3p
rs377111580 chr13:50048986    C/T
rs769728617 chr13:50048992    CA/C
rs1460126106 chr13:50049003    C/A
rs1460126106 chr13:50049003    C/T
rs1468155921 chr13:50049001    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZNF597
chr16:3490445(-) A-I      intronic
chr16:3488033(-) A-I      intronic
chr16:3491941(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZNF597
chr16:3486200-3486201(-) m6A 3'UTR       27773535
chr16:3486213-3486214(-) m6A 3'UTR       27773535
chr16:3486225-3486226(-) m6A 3'UTR       27773535
chr16:3486433-3486434(-) m6A CDS       25456834//24981863//27773535//22608085
chr16:3486446-3486447(-) m6A CDS       25456834//24981863//27773535//22608085
chr16:3486485-3486486(-) m6A CDS       25456834//24981863//27773535//27371828//22608085
chr16:3486513-3486514(-) m6A CDS       25456834//24981863//27773535//27371828//22608085
chr16:3486549-3486550(-) m6A CDS       25456834//24981863//27773535//27371828//22575960//22608085
chr16:3486556-3486557(-) m6A CDS       25456834//24981863//27773535//27371828//22575960//22608085
chr16:3486581-3486582(-) m6A CDS       25456834//24981863//27773535//27371828//22575960//22608085
chr16:3486616-3486617(-) m6A CDS       25456834//24981863//27773535//27371828//22575960//22608085
chr16:3486709-3486710(-) m6A CDS       24981863//27773535//22608085
chr16:3486736-3486737(-) m6A CDS       24981863//27773535//22608085
chr16:3486833-3486834(-) m6A CDS       24981863//27773535//22608085
chr16:3486858-3486859(-) m6A CDS       24981863//27773535//22608085
chr16:3486873-3486874(-) m6A CDS       24981863//27773535//22575960//22608085
chr16:3486901-3486902(-) m6A CDS       24981863//27773535//22575960//22608085
chr16:3487068-3487069(-) m6A CDS       24981863//27773535//22575960//22608085
chr16:3487097-3487098(-) m6A CDS       24981863//27773535//22575960//22608085
chr16:3487149-3487150(-) m6A CDS       24981863//27773535//22608085
chr16:3487207-3487208(-) m6A CDS       24981863//27773535//27371828//22608085
chr16:3487286-3487287(-) m6A CDS       24981863//27773535//22608085
chr16:3487305-3487306(-) m6A CDS       24981863//27773535//22608085
chr16:3487324-3487325(-) m6A CDS       24981863//27773535//22608085
chr16:3487373-3487374(-) m6A CDS       24981863//27773535//22608085
chr16:3487399-3487400(-) m6A CDS       24981863//27773535//22608085
chr16:3487485-3487486(-) m6A CDS       24981863//27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
ZNF597
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-1-3p
Interactor2: ZNF597

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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