Basic Information:

  VIRBase ID:  

HHID00098948

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:  MIMAT0004489          FYTTD1:  NM_032288     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-16-1-3p	FYTTD1
miRBase Accession/Entrez ID	MIMAT0004489	84248
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	UIF

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-16-1-3p	rs377111580 chr13:50048986    C/T rs769728617 chr13:50048992    CA/C rs1460126106 chr13:50049003    C/A rs1460126106 chr13:50049003    C/T rs1468155921 chr13:50049001    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FYTTD1	chr3:197478890(+) A-I      intronic chr3:197478359(+) A-I      intronic chr3:197478352(+) A-I      intronic chr3:197478346(+) A-I      intronic chr3:197478947(+) A-I      intronic chr3:197491850(+) A-I      intronic chr3:197492784(+) A-I      intronic chr3:197492914(+) A-I      intronic chr3:197498068(+) A-I      intronic chr3:197498300(+) A-I      intronic chr3:197498779(+) A-I      intronic chr3:197498854(+) A-I      intronic chr3:197499609(+) A-I      intronic chr3:197499723(+) A-I      intronic chr3:197506133(+) A-I      intronic chr3:197506134(+) A-I      intronic chr3:197507103(+) A-I      intronic chr3:197507517(+) A-I      intronic chr3:197491889(+) A-I      intronic chr3:197478823(+) A-I      intronic chr3:197499685(+) A-I      intronic chr3:197507543(+) A-I      intronic chr3:197507550(+) A-I      intronic chr3:197507559(+) A-I      intronic chr3:197484486(+) A-I      intronic chr3:197484496(+) A-I      intronic chr3:197491862(+) A-I      intronic chr3:197491395(+) A-I      intronic chr3:197491896(+) A-I      intronic chr3:197491397(+) A-I      intronic chr3:197491904(+) A-I      intronic chr3:197478944(+) A-I      intronic chr3:197491392(+) A-I      intronic chr3:197491356(+) A-I      intronic chr3:197490420(+) A-I      intronic chr3:197489632(+) A-I      intronic chr3:197492684(+) A-I      intronic chr3:197485002(+) A-I      intronic chr3:197484963(+) A-I      intronic chr3:197484957(+) A-I      intronic chr3:197484936(+) A-I      intronic chr3:197478927(+) A-I      intronic chr3:197491403(+) A-I      intronic chr3:197491426(+) A-I      intronic chr3:197489619(+) A-I      intronic chr3:197491459(+) A-I      intronic chr3:197491465(+) A-I      intronic chr3:197491469(+) A-I      intronic chr3:197491473(+) A-I      intronic chr3:197478913(+) A-I      intronic chr3:197491847(+) A-I      intronic chr3:197491860(+) A-I      intronic chr3:197491441(+) A-I      intronic chr3:197482559(+) A-I      5'UTR chr3:197482568(+) A-I      5'UTR chr3:197482573(+) A-I      5'UTR chr3:197482581(+) A-I      5'UTR chr3:197507599(+) A-I      intronic chr3:197499754(+) A-I      intronic chr3:197484515(+) A-I      intronic chr3:197493370(+) A-I      intronic chr3:197507688(+) A-I      intronic chr3:197489185(+) A-I      intronic chr3:197506495(+) A-I      intronic chr3:197507596(+) A-I      intronic chr3:197484983(+) A-I      intronic chr3:197478292(+) A-I      intronic chr3:197478288(+) A-I      intronic chr3:197492746(+) A-I      intronic chr3:197499560(+) A-I      intronic chr3:197491325(+) A-I      intronic chr3:197478370(+) A-I      intronic chr3:197498296(+) A-I      intronic chr3:197478882(+) A-I      intronic chr3:197484385(+) A-I      intronic chr3:197506165(+) A-I      intronic chr3:197492557(+) A-I      intronic chr3:197478981(+) A-I      intronic chr3:197507518(+) A-I      intronic chr3:197491820(+) A-I      intronic chr3:197492483(+) A-I      intronic chr3:197492582(+) A-I      intronic chr3:197489498(+) A-I      intronic chr3:197498365(+) A-I      intronic chr3:197478397(+) A-I      intronic chr3:197499619(+) A-I      intronic chr3:197489499(+) A-I      intronic chr3:197507094(+) A-I      intronic chr3:197508051(+) A-I      intronic chr3:197507170(+) A-I      intronic chr3:197478919(+) A-I      intronic chr3:197492682(+) A-I      intronic chr3:197478420(+) A-I      intronic chr3:197478956(+) A-I      intronic chr3:197497997(+) A-I      intronic chr3:197478930(+) A-I      intronic chr3:197492596(+) A-I      intronic chr3:197506471(+) A-I      intronic chr3:197508064(+) A-I      intronic chr3:197491786(+) A-I      intronic chr3:197493407(+) A-I      intronic chr3:197507618(+) A-I      intronic chr3:197507999(+) A-I      intronic chr3:197499554(+) A-I      intronic chr3:197492495(+) A-I      intronic chr3:197478361(+) A-I      intronic chr3:197499509(+) A-I      intronic chr3:197499663(+) A-I      intronic chr3:197497531(+) A-I      intronic chr3:197508038(+) A-I      intronic chr3:197491924(+) A-I      intronic chr3:197506535(+) A-I      intronic chr3:197508065(+) A-I      intronic chr3:197478427(+) A-I      intronic chr3:197497496(+) A-I      intronic chr3:197497655(+) A-I      intronic chr3:197499583(+) A-I      intronic chr3:197506030(+) A-I      intronic chr3:197499732(+) A-I      intronic chr3:197507101(+) A-I      intronic chr3:197504655(+) A-I      intronic chr3:197497571(+) A-I      intronic chr3:197498884(+) A-I      intronic chr3:197506466(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FYTTD1	chr3:197478420(+) A-G intron -    22484847 chr3:197481534(+) C-T intron -    22484847 chr3:197481538(+) C-T intron -    22484847 chr3:197481539(+) T-C intron -    22484847 chr3:197484385(+) A-G intron -    22484847 chr3:197484983(+) A-G intron -    22484847 chr3:197491325(+) A-G intron -    22484847 chr3:197491924(+) A-G intron -    22484847 chr3:197492746(+) A-G intron -    22484847 chr3:197492749(+) A-G intron -    22484847 chr3:197497438(+) A-G intron -    22484847 chr3:197497531(+) A-G intron -    22484847 chr3:197497997(+) A-G intron -    22484847 chr3:197498794(+) A-G intron -    22484847 chr3:197498884(+) A-G intron -    22484847 chr3:197499732(+) A-G intron -    22484847 chr3:197507094(+) A-G intron -    22484847 chr3:197507518(+) A-G intron -    22484847 chr3:197507553(+) A-G intron -    22484847 chr3:197508001(+) A-G intron -    22484847 chr3:197508051(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FYTTD1	chr3:197476453-197476454(+) m6A 5'UTR//CDS//intron       24284625 chr3:197476473-197476474(+) m6A 5'UTR//CDS//intron       24284625 chr3:197476482-197476483(+) m6A 5'UTR//CDS//intron       24284625 chr3:197476846-197476847(+) m6A CDS//intron       - chr3:197476918-197476919(+) m6A CDS//intron       - chr3:197495334-197495335(+) Tm 3'UTR//CDS       - chr3:197497010-197497011(+) m6A 3'UTR//CDS//intron       24981863 chr3:197497042-197497043(+) m6A 3'UTR//CDS//intron       24981863 chr3:197497052-197497053(+) m6A 3'UTR//CDS//intron       24981863 chr3:197497073-197497074(+) m6A 3'UTR//CDS//intron       24981863 chr3:197497094-197497095(+) m6A 3'UTR//CDS//intron       24981863 chr3:197505318-197505319(+) m6A CDS//exon       24981863 chr3:197505331-197505332(+) m6A CDS//exon       24981863 chr3:197508722-197508723(+) m6A CDS//exon       24284625//24981863//22608085 chr3:197508796-197508797(+) m6A 3'UTR//exon       24284625//24981863//22608085 chr3:197508859-197508860(+) m6A 3'UTR//exon       24284625//24981863//22608085 chr3:197509429-197509430(+) m6A 3'UTR       22575960 chr3:197509552-197509553(+) m6A 3'UTR       24981863//27773535 chr3:197509570-197509571(+) m6A 3'UTR       24981863 chr3:197509580-197509581(+) m6A 3'UTR       24981863 chr3:197509814-197509815(+) Y 3'UTR       26075521

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-16-1-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	FYTTD1	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-16-1-3p
Interactor2: FYTTD1

Evidence Support:

Weak-Evidence	Illumina sequencing
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32223537	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Calu-3 cells	Interactor2 expression	Upregulation
Description	The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.