Basic Information:

  VIRBase ID:  

HHID00098947

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:  MIMAT0004489          RANBP17:  NM_022897     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-16-1-3p	RANBP17
miRBase Accession/Entrez ID	MIMAT0004489	64901
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-16-1-3p	rs377111580 chr13:50048986    C/T rs769728617 chr13:50048992    CA/C rs1460126106 chr13:50049003    C/A rs1460126106 chr13:50049003    C/T rs1468155921 chr13:50049001    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RANBP17	chr5:170461156(+) A-I      intronic chr5:170461209(+) A-I      intronic chr5:170710721(+) A-I      intronic chr5:170390614(+) A-I      intronic chr5:170390612(+) A-I      intronic chr5:170552869(+) A-I      intronic chr5:170638395(+) A-I      intronic chr5:170390611(+) A-I      intronic chr5:170390610(+) A-I      intronic chr5:170390608(+) A-I      intronic chr5:170402412(+) A-I      intronic chr5:170461223(+) A-I      intronic chr5:170461210(+) A-I      intronic chr5:170331046(+) A-I      intronic chr5:170475226(+) A-I      intronic chr5:170725062(+) A-I      intronic chr5:170725082(+) A-I      intronic chr5:170658080(+) A-I      intronic chr5:170694584(+) A-I      intronic chr5:170672436(+) A-I      intronic chr5:170581898(+) A-I      intronic chr5:170581915(+) A-I      intronic chr5:170331037(+) A-I      intronic chr5:170331034(+) A-I      intronic chr5:170331015(+) A-I      intronic chr5:170330992(+) A-I      intronic chr5:170581919(+) A-I      intronic chr5:170672012(+) A-I      intronic chr5:170461115(+) A-I      intronic chr5:170504143(+) A-I      intronic chr5:170504155(+) A-I      intronic chr5:170532657(+) A-I      intronic chr5:170552060(+) A-I      intronic chr5:170581918(+) A-I      intronic chr5:170694579(+) A-I      intronic chr5:170581894(+) A-I      intronic chr5:170581924(+) A-I      intronic chr5:170461252(+) A-I      intronic chr5:170475284(+) A-I      intronic chr5:170390600(+) A-I      intronic chr5:170552178(+) A-I      intronic chr5:170552222(+) A-I      intronic chr5:170658141(+) A-I      intronic chr5:170670975(+) A-I      intronic chr5:170670988(+) A-I      intronic chr5:170671999(+) A-I      intronic chr5:170671986(+) A-I      intronic chr5:170649747(+) A-I      intronic chr5:170649728(+) A-I      intronic chr5:170649662(+) A-I      intronic chr5:170658070(+) A-I      intronic chr5:170725083(+) A-I      intronic chr5:170477564(+) A-I      intronic chr5:170477568(+) A-I      intronic chr5:170461114(+) A-I      intronic chr5:170461096(+) A-I      intronic chr5:170505360(+) A-I      intronic chr5:170672036(+) A-I      intronic chr5:170568574(+) A-I      intronic chr5:170586762(+) A-I      intronic chr5:170557540(+) A-I      intronic chr5:170684854(+) A-I      intronic chr5:170532601(+) A-I      intronic chr5:170675351(+) A-I      intronic chr5:170552933(+) A-I      intronic chr5:170638369(+) A-I      intronic chr5:170638405(+) A-I      intronic chr5:170495660(+) A-I      intronic chr5:170724978(+) A-I      intronic chr5:170504089(+) A-I      intronic chr5:170693912(+) A-I      intronic chr5:170586812(+) A-I      intronic chr5:170671276(+) A-I      intronic chr5:170366625(+) A-I      intronic chr5:170366658(+) A-I      intronic chr5:170504139(+) A-I      intronic chr5:170559568(+) A-I      intronic chr5:170650383(+) A-I      intronic chr5:170681099(+) A-I      intronic chr5:170568532(+) A-I      intronic chr5:170671476(+) A-I      intronic chr5:170657687(+) A-I      intronic chr5:170532519(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RANBP17	chr5:170492370(+) A-I intron -    21960545

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-16-1-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	RANBP17	Exosome Blood     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-16-1-3p
Interactor2: RANBP17

Evidence Support:

Weak-Evidence	Illumina sequencing
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32223537	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Calu-3 cells	Interactor2 expression	Upregulation
Description	The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.