Detail Information

Basic Information:


  VIRBase ID:  

HHID00098942

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:           RAB23:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-1-3p RAB23
miRBase
Accession/Entrez ID		 MIMAT0004489 51715
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HSPC137

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-1-3p
rs377111580 chr13:50048986    C/T
rs769728617 chr13:50048992    CA/C
rs1460126106 chr13:50049003    C/A
rs1460126106 chr13:50049003    C/T
rs1468155921 chr13:50049001    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RAB23
chr6:57062820(-) A-I      intronic
chr6:57062847(-) A-I      intronic
chr6:57062620(-) A-I      intronic
chr6:57077585(-) A-I      intronic
chr6:57077598(-) A-I      intronic
chr6:57077563(-) A-I      intronic
chr6:57079210(-) A-I      intronic
chr6:57077625(-) A-I      intronic
chr6:57079201(-) A-I      intronic
chr6:57062853(-) A-I      intronic
chr6:57062863(-) A-I      intronic
chr6:57062675(-) A-I      intronic
chr6:57062816(-) A-I      intronic
chr6:57062669(-) A-I      intronic
chr6:57062629(-) A-I      intronic
chr6:57053991(-) A-I      3'UTR
chr6:57054006(-) A-I      3'UTR
chr6:57054011(-) A-I      3'UTR
chr6:57053989(-) A-I      3'UTR
chr6:57053982(-) A-I      3'UTR
chr6:57053979(-) A-I      3'UTR
chr6:57053992(-) A-I      3'UTR
chr6:57053994(-) A-I      3'UTR
chr6:57054021(-) A-I      3'UTR
chr6:57054028(-) A-I      3'UTR
chr6:57054030(-) A-I      3'UTR
chr6:57054031(-) A-I      3'UTR
chr6:57054039(-) A-I      3'UTR
chr6:57054044(-) A-I      3'UTR
chr6:57054055(-) A-I      3'UTR
chr6:57066131(-) A-I      intronic
chr6:57079148(-) A-I      intronic
chr6:57073240(-) A-I      intronic
chr6:57067812(-) A-I      intronic
chr6:57062665(-) A-I      intronic
chr6:57062661(-) A-I      intronic
chr6:57079265(-) A-I      intronic
chr6:57083445(-) A-I      intronic
chr6:57062777(-) A-I      intronic
chr6:57062599(-) A-I      intronic
chr6:57076222(-) A-I      intronic
chr6:57066016(-) A-I      intronic
chr6:57062697(-) A-I      intronic
chr6:57062846(-) A-I      intronic
chr6:57066113(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED RAB23
chr6:57057484(-) T-C intron -    22484847
chr6:57083598(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RAB23
chr6:57054957-57054958(-) m6A 3'UTR       27773535
chr6:57054990-57054991(-) m6A 3'UTR       24209618//27773535//22608085
chr6:57055060-57055061(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr6:57055090-57055091(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr6:57055133-57055134(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr6:57055166-57055167(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr6:57055207-57055208(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr6:57055240-57055241(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr6:57055292-57055293(-) m6A CDS       24209618//24981863//27773535//22575960//22608085
chr6:57055302-57055303(-) m6A CDS       24209618//24981863//27773535//22575960//22608085
chr6:57055309-57055310(-) m6A CDS       24209618//22575960//22608085
chr6:57055318-57055319(-) m6A CDS       24209618//22575960//22608085
chr6:57086625-57086626(-) m6A 5'UTR       27773536
chr6:57086730-57086731(-) m6A 5'UTR       27773536
chr6:57086897-57086898(-) m6A 5'UTR       24209618//27773536
chr6:57086942-57086943(-) m6A 5'UTR       24209618//27773536
chr6:57087062-57087063(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
RAB23
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-1-3p
Interactor2: RAB23

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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