Detail Information

Basic Information:


  VIRBase ID:  

HHID00098941

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:           ZBTB21:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-1-3p ZBTB21
miRBase
Accession/Entrez ID		 MIMAT0004489 49854
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ZNF295

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-1-3p
rs377111580 chr13:50048986    C/T
rs769728617 chr13:50048992    CA/C
rs1460126106 chr13:50049003    C/A
rs1460126106 chr13:50049003    C/T
rs1468155921 chr13:50049001    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZBTB21
chr21:43424336(-) A-I      intronic
chr21:43424365(-) A-I      intronic
chr21:43417638(-) A-I      intronic
chr21:43417625(-) A-I      intronic
chr21:43426442(-) A-I      intronic
chr21:43428503(-) A-I      intronic
chr21:43428518(-) A-I      intronic
chr21:43428545(-) A-I      intronic
chr21:43417303(-) A-I      intronic
chr21:43417493(-) A-I      intronic
chr21:43418439(-) A-I      intronic
chr21:43424176(-) A-I      intronic
chr21:43424237(-) A-I      intronic
chr21:43424241(-) A-I      intronic
chr21:43424247(-) A-I      intronic
chr21:43426412(-) A-I      intronic
chr21:43426448(-) A-I      intronic
chr21:43426472(-) A-I      intronic
chr21:43428358(-) A-I      intronic
chr21:43426405(-) A-I      intronic
chr21:43428603(-) A-I      intronic
chr21:43428611(-) A-I      intronic
chr21:43418546(-) A-I      intronic
chr21:43424273(-) A-I      intronic
chr21:43414828(-) A-I      intronic
chr21:43428638(-) A-I      intronic
chr21:43418393(-) A-I      intronic
chr21:43418386(-) A-I      intronic
chr21:43417304(-) A-I      intronic
chr21:43424233(-) A-I      intronic
chr21:43417563(-) A-I      intronic
chr21:43424382(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZBTB21
chr21:43409954-43409955(-) m6A 3'UTR       27773535
chr21:43410025-43410026(-) m6A 3'UTR       27773535
chr21:43410048-43410049(-) m6A 3'UTR       27773535
chr21:43410785-43410786(-) m6A 3'UTR       27773535
chr21:43410796-43410797(-) m6A 3'UTR       27773535
chr21:43410914-43410915(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr21:43410930-43410931(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr21:43410999-43411000(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr21:43411018-43411019(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr21:43411044-43411045(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr21:43411053-43411054(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr21:43411066-43411067(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr21:43411081-43411082(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr21:43411130-43411131(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr21:43411153-43411154(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr21:43411175-43411176(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr21:43411265-43411266(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr21:43411399-43411400(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr21:43411604-43411605(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr21:43411648-43411649(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085
chr21:43411697-43411698(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085
chr21:43411760-43411761(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr21:43411781-43411782(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr21:43411802-43411803(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr21:43411909-43411910(-) m6A CDS//exon       24284625//27773535//27371828//22608085
chr21:43412051-43412052(-) m6A CDS//intron       24284625//27773535//22608085
chr21:43412089-43412090(-) m6A CDS//intron       24284625//27773535//22608085
chr21:43412116-43412117(-) m6A CDS//intron       24284625//27773535//22608085
chr21:43412222-43412223(-) m6A CDS//intron       24284625//24981863//26404942//27773535//27371828//22575960//22608085
chr21:43412260-43412261(-) m6A CDS//intron       24284625//24981863//26404942//27773535//27371828//22575960//22608085
chr21:43412396-43412397(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr21:43412418-43412419(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr21:43412430-43412431(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr21:43412557-43412558(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr21:43412576-43412577(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr21:43412581-43412582(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr21:43412738-43412739(-) m6A CDS//intron       24284625//25456834//24981863//27773535//27371828//22608085
chr21:43412767-43412768(-) m6A CDS//intron       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr21:43412777-43412778(-) m6A CDS//intron       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr21:43412796-43412797(-) m6A CDS//intron       24284625//25456834//24981863//26404942//27371828//27773536//22575960//22608085
chr21:43412810-43412811(-) m6A CDS//intron       24284625//25456834//24981863//26404942//27371828//27773536//22575960//22608085
chr21:43412879-43412880(-) m6A CDS//intron       24284625//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr21:43412888-43412889(-) m6A CDS//intron       24284625//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr21:43412913-43412914(-) m6A CDS//intron       24284625//25456834//24981863//27371828//27773536//22575960//22608085
chr21:43412954-43412955(-) m6A CDS//intron       24284625//25456834//24981863//27371828//27773536//22575960//22608085
chr21:43413027-43413028(-) m6A CDS//intron       24284625
chr21:43413227-43413228(-) m6A CDS//intron       24284625//24981863//27371828//22608085
chr21:43413287-43413288(-) m6A CDS//intron       24284625//24981863//26404942//27773535//27371828//22608085
chr21:43413321-43413322(-) m6A CDS//intron       24284625//24981863//26404942//27773535//27371828//22608085
chr21:43413342-43413343(-) m6A CDS//intron       24284625//24981863//26404942//27773535//27371828//22608085
chr21:43413382-43413383(-) m6A CDS//intron       24284625//24981863//26404942//27773535//27371828//22608085
chr21:43413439-43413440(-) m6A CDS//intron       24284625//24981863//27773535//27371828//22608085
chr21:43413461-43413462(-) m6A CDS//intron       24284625//24981863//27773535//27371828//22608085
chr21:43413616-43413617(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr21:43413625-43413626(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr21:43413720-43413721(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22608085
chr21:43413779-43413780(-) m6A CDS//intron       24284625//24209618//24981863//27773535//27371828//22608085
chr21:43413843-43413844(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22608085
chr21:43413892-43413893(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22608085
chr21:43413950-43413951(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr21:43414002-43414003(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085
chr21:43414091-43414092(-) m6A CDS//intron       24284625//24209618//24981863//27773535//27371828//22608085
chr21:43414123-43414124(-) m6A CDS//intron       24284625//24209618//24981863//27773535//27371828//22608085
chr21:43414212-43414213(-) m6A 5'UTR//intron       24284625//24981863//27773535//27371828//22608085
chr21:43422551-43422552(-) m6A 5'UTR//intron       27371828
chr21:43429682-43429683(-) m6A 5'UTR//intron       27371828
chr21:43429694-43429695(-) m6A 5'UTR//intron       24981863//27371828
chr21:43430363-43430364(-) m6A 5'UTR//exon       24981863//27371828
chr21:43430370-43430371(-) m6A 5'UTR//exon       24981863//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
ZBTB21
Chromatin K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-1-3p
Interactor2: ZBTB21

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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