Detail Information

Basic Information:


  VIRBase ID:  

HHID00098937

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:           INTS6:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-1-3p INTS6
miRBase
Accession/Entrez ID		 MIMAT0004489 26512
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DBI-1//DDX26//DDX26A//DICE1//HDB//INT6//Notchl2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-1-3p
rs377111580 chr13:50048986    C/T
rs769728617 chr13:50048992    CA/C
rs1460126106 chr13:50049003    C/A
rs1460126106 chr13:50049003    C/T
rs1468155921 chr13:50049001    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR INTS6
chr13:52016500(-) A-I      intronic
chr13:52018468(-) A-I      intronic
chr13:52016448(-) A-I      intronic
chr13:52016457(-) A-I      intronic
chr13:52016489(-) A-I      intronic
chr13:52016498(-) A-I      intronic
chr13:52018454(-) A-I      intronic
chr13:51978107(-) A-I      intronic
chr13:52018491(-) A-I      intronic
chr13:51981906(-) A-I      intronic
chr13:52018311(-) A-I      intronic
chr13:52018492(-) A-I      intronic
chr13:52018522(-) A-I      intronic
chr13:52018359(-) A-I      intronic
chr13:52018529(-) A-I      intronic
chr13:51981961(-) A-I      intronic
chr13:51977636(-) A-I      intronic
chr13:51983352(-) A-I      intronic
chr13:52018487(-) A-I      intronic
chr13:52014226(-) A-I      intronic
chr13:52018663(-) A-I      intronic
chr13:52016153(-) A-I      intronic
chr13:51982500(-) A-I      intronic
chr13:52002576(-) A-I      intronic
chr13:52016094(-) A-I      intronic
chr13:52003869(-) A-I      intronic
chr13:52016176(-) A-I      intronic
chr13:52003737(-) A-I      intronic
chr13:52016152(-) A-I      intronic
chr13:52011138(-) A-I      intronic
chr13:52017806(-) A-I      intronic
chr13:52007461(-) A-I      intronic
chr13:52016133(-) A-I      intronic
chr13:51982444(-) A-I      intronic
chr13:52018680(-) A-I      intronic
chr13:51982484(-) A-I      intronic
chr13:52012023(-) A-I      intronic
chr13:51982417(-) A-I      intronic
chr13:52018776(-) A-I      intronic
chr13:52018798(-) A-I      intronic
chr13:51982428(-) A-I      intronic
chr13:51977554(-) A-I      intronic
chr13:52018802(-) A-I      intronic
chr13:51973432(-) A-I      intronic
chr13:52018286(-) A-I      intronic
chr13:51949367(-) A-I      intronic
chr13:52016121(-) A-I      intronic
chr13:51982454(-) A-I      intronic
chr13:52014265(-) A-I      intronic
chr13:52003787(-) A-I      intronic
chr13:52012114(-) A-I      intronic
chr13:52016089(-) A-I      intronic
chr13:52018490(-) A-I      intronic
chr13:51982418(-) A-I      intronic
chr13:52003788(-) A-I      intronic
chr13:52018822(-) A-I      intronic
chr13:52018823(-) A-I      intronic
chr13:51977529(-) A-I      intronic
chr13:51985626(-) A-I      intronic
chr13:51982474(-) A-I      intronic
chr13:51982139(-) A-I      intronic
chr13:52018260(-) A-I      intronic
chr13:52003676(-) A-I      intronic
chr13:52018386(-) A-I      intronic
chr13:52018369(-) A-I      intronic
chr13:52018693(-) A-I      intronic
chr13:51981980(-) A-I      intronic
chr13:52018389(-) A-I      intronic
chr13:52002577(-) A-I      intronic
chr13:51982070(-) A-I      intronic
chr13:52018773(-) A-I      intronic
chr13:52017776(-) A-I      intronic
chr13:52016081(-) A-I      intronic
chr13:52018520(-) A-I      intronic
chr13:52018763(-) A-I      intronic
chr13:52018761(-) A-I      intronic
chr13:52016072(-) A-I      intronic
chr13:52018828(-) A-I      intronic
chr13:52016049(-) A-I      intronic
chr13:52018310(-) A-I      intronic
chr13:52018859(-) A-I      intronic
chr13:52002732(-) A-I      intronic
chr13:52018880(-) A-I      intronic
chr13:51982041(-) A-I      intronic
chr13:52016396(-) A-I      intronic
chr13:52018682(-) A-I      intronic
chr13:52018457(-) A-I      intronic
chr13:52016886(-) A-I      intronic
chr13:52018434(-) A-I      intronic
chr13:52018846(-) A-I      intronic
chr13:52016360(-) A-I      intronic
chr13:52018349(-) A-I      intronic
chr13:51991879(-) A-I      intronic
chr13:52007455(-) A-I      intronic
chr13:52018507(-) A-I      intronic
chr13:52018514(-) A-I      intronic
chr13:51957091(-) A-I      intronic
chr13:52017225(-) A-I      intronic
chr13:52018719(-) A-I      intronic
chr13:52018449(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED INTS6
chr13:51981906(-) A-G intron -    22484847
chr13:52016360(-) A-G intron -    22484847
chr13:52018449(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase INTS6
chr13:51928405-51928406(-) m6A exon       27773535
chr13:51928439-51928440(-) m6A exon       27773535
chr13:51928457-51928458(-) m6A exon       27773535
chr13:51939482-51939483(-) m6A 3'UTR//intron       27773535
chr13:51939544-51939545(-) m6A 3'UTR//intron       27773535
chr13:51939580-51939581(-) m6A 3'UTR//intron       27773535
chr13:51939657-51939658(-) m6A 3'UTR//exon//intron       27773535
chr13:51939675-51939676(-) m6A 3'UTR//exon//intron       27773535
chr13:51939826-51939827(-) m6A 3'UTR//exon//intron       24981863//27773535
chr13:51939945-51939946(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr13:51939956-51939957(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr13:51941978-51941979(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr13:51941983-51941984(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr13:51943117-51943118(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr13:51943190-51943191(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr13:51943207-51943208(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr13:51943266-51943267(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085
chr13:51943373-51943374(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//27371828//22608085
chr13:51943388-51943389(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//27371828//22608085
chr13:51943437-51943438(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085
chr13:51948362-51948363(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr13:51948404-51948405(-) m6A 3'UTR//CDS//exon       27773535
chr13:51948426-51948427(-) m6A 3'UTR//CDS//exon       27773535
chr13:51948446-51948447(-) m6A 3'UTR//CDS//exon       27773535
chr13:51948506-51948507(-) m6A 3'UTR//CDS//exon       27773535
chr13:51948524-51948525(-) m6A 3'UTR//CDS//exon       27773535
chr13:51948536-51948537(-) m6A 3'UTR//CDS//exon       27773535
chr13:51948852-51948853(-) m6A 3'UTR//CDS//exon       27773535
chr13:51959037-51959038(-) m6A 5'UTR//intron       27773535
chr13:51959042-51959043(-) m6A 5'UTR//intron       27773535
chr13:51959053-51959054(-) m6A 5'UTR//intron       27773535
chr13:51959059-51959060(-) m6A 5'UTR//intron       27773535
chr13:51961589-51961590(-) m6A 3'UTR//CDS//exon       -
chr13:51961602-51961603(-) m6A 3'UTR//CDS//exon       -
chr13:51961617-51961618(-) m6A 3'UTR//CDS//exon       -
chr13:51963476-51963477(-) m6A 3'UTR//CDS//intron       24981863
chr13:51963492-51963493(-) m6A 3'UTR//CDS//intron       24981863
chr13:52024367-52024368(-) m6A 3'UTR//intron       27773535
chr13:52025017-52025018(-) m6A 3'UTR//intron       27773535
chr13:52025061-52025062(-) m6A 3'UTR//intron       27773535
chr13:52025089-52025090(-) m6A 3'UTR//intron       27773535
chr13:52025107-52025108(-) m6A 3'UTR//intron       27773535
chr13:52025173-52025174(-) m6A CDS//exon       27773535
chr13:52025219-52025220(-) m6A CDS//exon       27773535
chr13:52025247-52025248(-) m6A CDS//exon       27773535
chr13:52025263-52025264(-) m6A CDS//exon       27773535
chr13:52026159-52026160(-) m6A CDS//exon       -
chr13:52026177-52026178(-) m6A CDS//exon       -
chr13:52026635-52026636(-) m6A 5'UTR//CDS//exon       27773536
chr13:52026788-52026789(-) m6A 5'UTR//intron       27773536
chr13:52026794-52026795(-) m6A 5'UTR//intron       27773536
chr13:52026816-52026817(-) m6A 5'UTR//intron       25456834//27773536
chr13:52026928-52026929(-) m6A 5'UTR//intron       25456834//24981863//27371828//27773536//22608085
chr13:52026936-52026937(-) m6A 5'UTR//intron       25456834//24981863//27371828//27773536//22608085
chr13:52026958-52026959(-) m6A 5'UTR//intron       25456834//24981863//27371828//27773536//22608085
chr13:52026988-52026989(-) m6A 5'UTR//intron       25456834//27371828//27773536
chr13:52027107-52027108(-) m6A 5'UTR//intron       24981863//27371828//27773536
chr13:52027194-52027195(-) m6A 5'UTR//intron       24981863//27773536
chr13:52028252-52028253(-) m6A 5'UTR       -
chr13:52028273-52028274(-) m6A 5'UTR       -
chr13:52028356-52028357(-) m6A 5'UTR       -
chr13:52028370-52028371(-) m6A 5'UTR       -
chr13:52028384-52028385(-) m6A 5'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
INTS6
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-1-3p
Interactor2: INTS6

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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