Detail Information

Basic Information:


  VIRBase ID:  

HHID00098935

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:           IKZF2:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-1-3p IKZF2
miRBase
Accession/Entrez ID		 MIMAT0004489 22807
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ANF1A2//HELIOS//ZNF1A2//ZNFN1A2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-1-3p
rs377111580 chr13:50048986    C/T
rs769728617 chr13:50048992    CA/C
rs1460126106 chr13:50049003    C/A
rs1460126106 chr13:50049003    C/T
rs1468155921 chr13:50049001    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR IKZF2
chr2:213885771(-) A-I      intronic
chr2:213906298(-) A-I      intronic
chr2:214000323(-) A-I      intronic
chr2:214000274(-) A-I      intronic
chr2:213944021(-) A-I      intronic
chr2:213943978(-) A-I      intronic
chr2:213906197(-) A-I      intronic
chr2:213906175(-) A-I      intronic
chr2:213906142(-) A-I      intronic
chr2:213906135(-) A-I      intronic
chr2:213905742(-) A-I      intronic
chr2:213905734(-) A-I      intronic
chr2:213905730(-) A-I      intronic
chr2:213905724(-) A-I      intronic
chr2:213905607(-) A-I      intronic
chr2:213903031(-) A-I      intronic
chr2:213902947(-) A-I      intronic
chr2:213902790(-) A-I      intronic
chr2:213902788(-) A-I      intronic
chr2:213902783(-) A-I      intronic
chr2:213897392(-) A-I      intronic
chr2:213897327(-) A-I      intronic
chr2:213897294(-) A-I      intronic
chr2:214000322(-) A-I      intronic
chr2:213897301(-) A-I      intronic
chr2:213953315(-) A-I      intronic
chr2:213897292(-) A-I      intronic
chr2:213906178(-) A-I      intronic
chr2:213897355(-) A-I      intronic
chr2:213906229(-) A-I      intronic
chr2:213953248(-) A-I      intronic
chr2:213905720(-) A-I      intronic
chr2:213948399(-) A-I      intronic
chr2:214000300(-) A-I      intronic
chr2:213897201(-) A-I      intronic
chr2:213906155(-) A-I      intronic
chr2:213906210(-) A-I      intronic
chr2:213993490(-) A-I      intronic
chr2:213905759(-) A-I      intronic
chr2:213897183(-) A-I      intronic
chr2:213897240(-) A-I      intronic
chr2:213956956(-) A-I      intronic
chr2:213998393(-) A-I      intronic
chr2:213906305(-) A-I      intronic
chr2:213993657(-) A-I      intronic
chr2:213956874(-) A-I      intronic
chr2:213905828(-) A-I      intronic
chr2:213906223(-) A-I      intronic
chr2:213906165(-) A-I      intronic
chr2:213943981(-) A-I      intronic
chr2:213981293(-) A-I      intronic
chr2:213873138(-) A-I      intronic
chr2:213897256(-) A-I      intronic
chr2:213897354(-) A-I      intronic
chr2:213897275(-) A-I      intronic
chr2:213948405(-) A-I      intronic
chr2:213979414(-) A-I      intronic
chr2:213905585(-) A-I      intronic
chr2:213953313(-) A-I      intronic
chr2:213895688(-) A-I      intronic
chr2:213906299(-) A-I      intronic
chr2:213903056(-) A-I      intronic
chr2:213979413(-) A-I      intronic
chr2:213977264(-) A-I      intronic
chr2:213953328(-) A-I      intronic
chr2:213998258(-) A-I      intronic
chr2:213906138(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED IKZF2
chr2:213897345(-) A-I intron -    21960545
chr2:213895688(-) A-G intron -    22484847
chr2:213895841(-) G-A intron -    22484847
chr2:213897201(-) A-G intron -    22484847
chr2:213897301(-) A-G intron -    22484847
chr2:213897345(-) A-G intron -    22484847
chr2:213897354(-) A-G intron -    22484847
chr2:213897355(-) A-G intron -    22484847
chr2:213902863(-) G-A intron -    22484847
chr2:213902921(-) A-G intron -    22484847
chr2:213903056(-) A-G intron -    22484847
chr2:213905828(-) A-G intron -    22484847
chr2:213906155(-) A-G intron -    22484847
chr2:213906165(-) A-G intron -    22484847
chr2:213906178(-) A-G intron -    22484847
chr2:213906198(-) A-G intron -    22484847
chr2:213906223(-) A-G intron -    22484847
chr2:213906229(-) A-G intron -    22484847
chr2:213906299(-) A-G intron -    22484847
chr2:213906305(-) A-G intron -    22484847
chr2:213918861(-) A-C intron -    22484847
chr2:213953248(-) A-G intron -    22484847
chr2:213956911(-) T-C intron -    22484847
chr2:213979666(-) A-T intron -    22484847
chr2:213979668(-) T-G intron -    22484847
chr2:213998427(-) T-A intron -    22484847
chr2:214000193(-) A-G intron -    22484847
chr2:214001116(-) C-T intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase IKZF2
chr2:213871587-213871588(-) m6A 3'UTR//exon       -
chr2:213871593-213871594(-) m6A 3'UTR//exon       -
chr2:213871623-213871624(-) m6A 3'UTR//exon       -
chr2:213871630-213871631(-) m6A 3'UTR//exon       -
chr2:213871690-213871691(-) m6A 3'UTR//exon       28052920
chr2:213871719-213871720(-) m6A 3'UTR//exon       28052920
chr2:213871897-213871898(-) m6A 3'UTR//exon       -
chr2:213872044-213872045(-) m6A 3'UTR//exon       25456834//28052920//27371828//22608085
chr2:213872062-213872063(-) m6A 3'UTR//exon       25456834//28052920//27371828//22608085
chr2:213872135-213872136(-) m6A 3'UTR//CDS//exon       24209618//25456834//24981863//28052920//27371828//22608085
chr2:213872174-213872175(-) m6A 3'UTR//CDS//exon       24209618//25456834//24981863//28052920//27371828//22575960//22608085
chr2:213872219-213872220(-) m6A 3'UTR//CDS//exon       24209618//25456834//24981863//28052920//27371828//22575960//22608085
chr2:213872266-213872267(-) m6A 3'UTR//CDS//exon       25456834//24981863//28052920//27371828//22575960//22608085
chr2:213872297-213872298(-) m6A 3'UTR//CDS//exon       25456834//24981863//28052920//27371828//22608085
chr2:213872371-213872372(-) m6A 3'UTR//CDS//exon       25456834//24981863//28052920//27371828//22608085
chr2:213872398-213872399(-) m6A 3'UTR//CDS//exon       25456834//24981863//28052920//27371828//22608085
chr2:213872500-213872501(-) m6A 3'UTR//CDS//exon       25456834//24981863//28052920//27371828//22608085
chr2:213872531-213872532(-) m6A 3'UTR//CDS//exon       25456834//24981863//28052920//27371828//22608085
chr2:213872550-213872551(-) m6A 3'UTR//CDS//exon       25456834//24981863//28052920//27371828//22608085
chr2:213872566-213872567(-) m6A 3'UTR//CDS//exon       25456834//24981863//28052920//27371828//22608085
chr2:213872711-213872712(-) m6A 3'UTR//CDS//exon       24981863//28052920//27371828//22608085
chr2:213872759-213872760(-) m6A 3'UTR//CDS//exon       24981863//28052920//27371828//22608085
chr2:213878584-213878585(-) m6A 3'UTR//CDS//exon//intron       -
chr2:213878615-213878616(-) m6A 3'UTR//CDS//exon//intron       -
chr2:213878632-213878633(-) m6A 3'UTR//CDS//exon//intron       -
chr2:214016908-214016909(-) m6A 5'UTR       25456834
chr2:214016983-214016984(-) m6A 5'UTR       24209618//25456834//22608085
chr2:214017041-214017042(-) m6A 5'UTR       24209618//25456834//22608085
chr2:214017117-214017118(-) m6A 5'UTR       24209618//25456834//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
IKZF2
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-1-3p
Interactor2: IKZF2

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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