Detail Information

Basic Information:


  VIRBase ID:  

HHID00098933

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:           EXOC5:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-1-3p EXOC5
miRBase
Accession/Entrez ID		 MIMAT0004489 10640
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HSEC10//PRO1912//SEC10//SEC10L1//SEC10P

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-1-3p
rs377111580 chr13:50048986    C/T
rs769728617 chr13:50048992    CA/C
rs1460126106 chr13:50049003    C/A
rs1460126106 chr13:50049003    C/T
rs1468155921 chr13:50049001    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR EXOC5
chr14:57680237(-) A-I      intronic
chr14:57709221(-) A-I      intronic
chr14:57708769(-) A-I      intronic
chr14:57680264(-) A-I      intronic
chr14:57709127(-) A-I      intronic
chr14:57678702(-) A-I      intronic
chr14:57678680(-) A-I      intronic
chr14:57680241(-) A-I      intronic
chr14:57678781(-) A-I      intronic
chr14:57709087(-) A-I      intronic
chr14:57708658(-) A-I      intronic
chr14:57678575(-) A-I      intronic
chr14:57709234(-) A-I      intronic
chr14:57678849(-) A-I      intronic
chr14:57697895(-) A-I      intronic
chr14:57680524(-) A-I      intronic
chr14:57708662(-) A-I      intronic
chr14:57678533(-) A-I      intronic
chr14:57680263(-) A-I      intronic
chr14:57678491(-) A-I      intronic
chr14:57679909(-) A-I      intronic
chr14:57680258(-) A-I      intronic
chr14:57678829(-) A-I      intronic
chr14:57707132(-) A-I      intronic
chr14:57680605(-) A-I      intronic
chr14:57679836(-) A-I      intronic
chr14:57678361(-) A-I      intronic
chr14:57680515(-) A-I      intronic
chr14:57680461(-) A-I      intronic
chr14:57669907(-) A-I      3'UTR
chr14:57669905(-) A-I      3'UTR
chr14:57669895(-) A-I      3'UTR
chr14:57669887(-) A-I      3'UTR
chr14:57707711(-) A-I      intronic
chr14:57707708(-) A-I      intronic
chr14:57680164(-) A-I      intronic
chr14:57708687(-) A-I      intronic
chr14:57678505(-) A-I      intronic
chr14:57680005(-) A-I      intronic
chr14:57678527(-) A-I      intronic
chr14:57678504(-) A-I      intronic
chr14:57708595(-) A-I      intronic
chr14:57707852(-) A-I      intronic
chr14:57680193(-) A-I      intronic
chr14:57708804(-) A-I      intronic
chr14:57681842(-) A-I      intronic
chr14:57679883(-) A-I      intronic
chr14:57679984(-) A-I      intronic
chr14:57680209(-) A-I      intronic
chr14:57679845(-) A-I      intronic
chr14:57709101(-) A-I      intronic
chr14:57680588(-) A-I      intronic
chr14:57708607(-) A-I      intronic
chr14:57678434(-) A-I      intronic
chr14:57678689(-) A-I      intronic
chr14:57709054(-) A-I      intronic
chr14:57680048(-) A-I      intronic
chr14:57711700(-) A-I      intronic
chr14:57678577(-) A-I      intronic
chr14:57679929(-) A-I      intronic
chr14:57680308(-) A-I      intronic
chr14:57707709(-) A-I      intronic
chr14:57680305(-) A-I      intronic
chr14:57707668(-) A-I      intronic
chr14:57678855(-) A-I      intronic
chr14:57680304(-) A-I      intronic
chr14:57709155(-) A-I      intronic
chr14:57707743(-) A-I      intronic
chr14:57680198(-) A-I      intronic
chr14:57678716(-) A-I      intronic
chr14:57707853(-) A-I      intronic
chr14:57678373(-) A-I      intronic
chr14:57669918(-) A-I      3'UTR
chr14:57669899(-) A-I      3'UTR
chr14:57669910(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED EXOC5
chr14:57709221(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase EXOC5
chr14:57671352-57671353(-) m6A 3'UTR       27773535
chr14:57673322-57673323(-) m6A 3'UTR       27773535
chr14:57673383-57673384(-) m6A 3'UTR       27773535
chr14:57675061-57675062(-) m6A 3'UTR//exon       27773535
chr14:57675187-57675188(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//27773535//22608085
chr14:57675192-57675193(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//27773535//22608085
chr14:57675204-57675205(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//27773535//22608085
chr14:57675402-57675403(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085
chr14:57675419-57675420(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085
chr14:57676291-57676292(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085
chr14:57676467-57676468(-) m6A 3'UTR//CDS//exon       27773535
chr14:57676695-57676696(-) m6A 3'UTR//CDS//exon       27773535
chr14:57676720-57676721(-) m6A 3'UTR//CDS//exon       27773535
chr14:57676730-57676731(-) m6A 3'UTR//CDS//exon       27773535
chr14:57676757-57676758(-) m6A 3'UTR//CDS//exon       27773535
chr14:57711053-57711054(-) m6A 3'UTR//CDS//exon//intron       27371828
chr14:57713500-57713501(-) m6A 3'UTR//CDS//exon       24981863
chr14:57713542-57713543(-) m6A 5'UTR//CDS//exon       24981863//27773535
chr14:57714358-57714359(-) m6A 5'UTR//CDS//exon       27773535
chr14:57735446-57735447(-) m6A 5'UTR//exon       27371828//27773536//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
EXOC5
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Membrane K562 cells     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-1-3p
Interactor2: EXOC5

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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