Detail Information

Basic Information:


  VIRBase ID:  

HHID00098930

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:           TP63:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-1-3p TP63
miRBase
Accession/Entrez ID
MIMAT0004489 8626
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AIS//B(p51A)//B(p51B)//EEC3//KET//LMS//NBP//OFC8//p40//p51//p53CP//p63//p73H//p73L//RHS//SHFM4//TP53CP//TP53L//TP73L

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-1-3p
rs377111580 chr13:50048986    C/T
rs769728617 chr13:50048992    CA/C
rs1460126106 chr13:50049003    C/A
rs1460126106 chr13:50049003    C/T
rs1468155921 chr13:50049001    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TP63
chr3:189402537(+) A-I      intronic
chr3:189402604(+) A-I      intronic
chr3:189407125(+) A-I      intronic
chr3:189407127(+) A-I      intronic
chr3:189412694(+) A-I      intronic
chr3:189412695(+) A-I      intronic
chr3:189565027(+) A-I      intronic
chr3:189402520(+) A-I      intronic
chr3:189390924(+) A-I      intronic
chr3:189592066(+) A-I      intronic
chr3:189565036(+) A-I      intronic
chr3:189564875(+) A-I      intronic
chr3:189565040(+) A-I      intronic
chr3:189564970(+) A-I      intronic
chr3:189564512(+) A-I      intronic
chr3:189495828(+) A-I      intronic
chr3:189495676(+) A-I      intronic
chr3:189480810(+) A-I      intronic
chr3:189596691(+) A-I      intronic
chr3:189591988(+) A-I      intronic
chr3:189390330(+) A-I      intronic
chr3:189390191(+) A-I      intronic
chr3:189390244(+) A-I      intronic
chr3:189424317(+) A-I      intronic
chr3:189386564(+) A-I      intronic
chr3:189390902(+) A-I      intronic
chr3:189457157(+) A-I      intronic
chr3:189390710(+) A-I      intronic
chr3:189459822(+) A-I      intronic
chr3:189390135(+) A-I      intronic
chr3:189390306(+) A-I      intronic
chr3:189459768(+) A-I      intronic
chr3:189386524(+) A-I      intronic
chr3:189390892(+) A-I      intronic
chr3:189564605(+) A-I      intronic
chr3:189424305(+) A-I      intronic
chr3:189390208(+) A-I      intronic
chr3:189565032(+) A-I      intronic
chr3:189390882(+) A-I      intronic
chr3:189390839(+) A-I      intronic
chr3:189593145(+) A-I      intronic
chr3:189390810(+) A-I      intronic
chr3:189390254(+) A-I      intronic
chr3:189406998(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TP63
chr3:189390254(+) A-I intron -    22327324
chr3:189360796(+) A-T intron -    22484847
chr3:189373205(+) A-G intron -    22484847
chr3:189381310(+) C-T intron -    22484847
chr3:189390191(+) A-G intron -    22484847
chr3:189390208(+) A-G intron -    22484847
chr3:189390244(+) A-G intron -    22484847
chr3:189390254(+) A-G intron -    22484847
chr3:189390306(+) A-G intron -    22484847
chr3:189390710(+) A-G intron -    22484847
chr3:189390734(+) A-G intron -    22484847
chr3:189390810(+) A-G intron -    22484847
chr3:189390839(+) A-G intron -    22484847
chr3:189390892(+) A-G intron -    22484847
chr3:189390902(+) A-G intron -    22484847
chr3:189402673(+) A-G intron -    22484847
chr3:189406998(+) A-G intron -    22484847
chr3:189457157(+) A-G intron -    22484847
chr3:189459822(+) A-G intron -    22484847
chr3:189470181(+) A-G intron -    22484847
chr3:189561962(+) C-T intron -    22484847
chr3:189561963(+) T-C intron -    22484847
chr3:189564602(+) A-G intron -    22484847
chr3:189564605(+) A-G intron -    22484847
chr3:189564971(+) A-G intron -    22484847
chr3:189565032(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TP63
chr3:189349291-189349292(+) m6A 5'UTR//exon       -
chr3:189349316-189349317(+) m6A CDS//exon       -
chr3:189455538-189455539(+) m6A CDS//exon       -
chr3:189455601-189455602(+) m6A CDS//exon       -
chr3:189507605-189507606(+) m6A CDS//exon//intron       -
chr3:189507616-189507617(+) m6A CDS//exon//intron       -
chr3:189526073-189526074(+) m6A CDS//exon//intron       -
chr3:189526088-189526089(+) m6A CDS//exon//intron       -
chr3:189526097-189526098(+) m6A CDS//exon//intron       -
chr3:189526145-189526146(+) m6A CDS//exon//intron       24981863
chr3:189526157-189526158(+) m6A CDS//exon//intron       24981863
chr3:189587179-189587180(+) m6A CDS//exon       -
chr3:189590662-189590663(+) m6A CDS//exon       -
chr3:189590700-189590701(+) m6A CDS//exon       -
chr3:189590781-189590782(+) m6A CDS//exon       -
chr3:189604250-189604251(+) m6A CDS       24981863
chr3:189607164-189607165(+) m6A CDS//intron       -
chr3:189607174-189607175(+) m6A CDS//intron       -
chr3:189608612-189608613(+) m6A CDS//intron       -
chr3:189612055-189612056(+) m6A 3'UTR//CDS       -
chr3:189612102-189612103(+) m6A 3'UTR//CDS       -
chr3:189612617-189612618(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
TP63
Chromatin K562 cells     -
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-1-3p
Interactor2: TP63

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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