Detail Information

Basic Information:


  VIRBase ID:  

HHID00098920

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:           ABCA1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-1-3p ABCA1
miRBase
Accession/Entrez ID		 MIMAT0004489 19
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ABC-1//ABC1//CERP//HDLCQTL13//HDLDT1//HPALP1//TGD

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-1-3p
rs377111580 chr13:50048986    C/T
rs769728617 chr13:50048992    CA/C
rs1460126106 chr13:50049003    C/A
rs1460126106 chr13:50049003    C/T
rs1468155921 chr13:50049001    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ABCA1
chr9:107685104(-) A-I      intronic
chr9:107660036(-) A-I      intronic
chr9:107659284(-) A-I      intronic
chr9:107659224(-) A-I      intronic
chr9:107659040(-) A-I      intronic
chr9:107628895(-) A-I      intronic
chr9:107568194(-) A-I      intronic
chr9:107567573(-) A-I      intronic
chr9:107567551(-) A-I      intronic
chr9:107567488(-) A-I      intronic
chr9:107624523(-) A-I      intronic
chr9:107624522(-) A-I      intronic
chr9:107659207(-) A-I      intronic
chr9:107659191(-) A-I      intronic
chr9:107659188(-) A-I      intronic
chr9:107567484(-) A-I      intronic
chr9:107623269(-) A-I      intronic
chr9:107623232(-) A-I      intronic
chr9:107623110(-) A-I      intronic
chr9:107567422(-) A-I      intronic
chr9:107566054(-) A-I      intronic
chr9:107565972(-) A-I      intronic
chr9:107622196(-) A-I      intronic
chr9:107622188(-) A-I      intronic
chr9:107622173(-) A-I      intronic
chr9:107622073(-) A-I      intronic
chr9:107619682(-) A-I      intronic
chr9:107619681(-) A-I      intronic
chr9:107619680(-) A-I      intronic
chr9:107619678(-) A-I      intronic
chr9:107619658(-) A-I      intronic
chr9:107685107(-) A-I      intronic
chr9:107685162(-) A-I      intronic
chr9:107659184(-) A-I      intronic
chr9:107659176(-) A-I      intronic
chr9:107622156(-) A-I      intronic
chr9:107567572(-) A-I      intronic
chr9:107567569(-) A-I      intronic
chr9:107619651(-) A-I      intronic
chr9:107567560(-) A-I      intronic
chr9:107567549(-) A-I      intronic
chr9:107567532(-) A-I      intronic
chr9:107567525(-) A-I      intronic
chr9:107567520(-) A-I      intronic
chr9:107619491(-) A-I      intronic
chr9:107619463(-) A-I      intronic
chr9:107619457(-) A-I      intronic
chr9:107619428(-) A-I      intronic
chr9:107612649(-) A-I      intronic
chr9:107612563(-) A-I      intronic
chr9:107612559(-) A-I      intronic
chr9:107685171(-) A-I      intronic
chr9:107567635(-) A-I      intronic
chr9:107685177(-) A-I      intronic
chr9:107659185(-) A-I      intronic
chr9:107659172(-) A-I      intronic
chr9:107567502(-) A-I      intronic
chr9:107659150(-) A-I      intronic
chr9:107659140(-) A-I      intronic
chr9:107659127(-) A-I      intronic
chr9:107659096(-) A-I      intronic
chr9:107685217(-) A-I      intronic
chr9:107687466(-) A-I      intronic
chr9:107687501(-) A-I      intronic
chr9:107660045(-) A-I      intronic
chr9:107682975(-) A-I      intronic
chr9:107683009(-) A-I      intronic
chr9:107683055(-) A-I      intronic
chr9:107683066(-) A-I      intronic
chr9:107682878(-) A-I      intronic
chr9:107681793(-) A-I      intronic
chr9:107676737(-) A-I      intronic
chr9:107623310(-) A-I      intronic
chr9:107623134(-) A-I      intronic
chr9:107622275(-) A-I      intronic
chr9:107622140(-) A-I      intronic
chr9:107643428(-) A-I      intronic
chr9:107659210(-) A-I      intronic
chr9:107623176(-) A-I      intronic
chr9:107623103(-) A-I      intronic
chr9:107659080(-) A-I      intronic
chr9:107682814(-) A-I      intronic
chr9:107659109(-) A-I      intronic
chr9:107568220(-) A-I      intronic
chr9:107624427(-) A-I      intronic
chr9:107619368(-) A-I      intronic
chr9:107676659(-) A-I      intronic
chr9:107643187(-) A-I      intronic
chr9:107650270(-) A-I      intronic
chr9:107619706(-) A-I      intronic
chr9:107643423(-) A-I      intronic
chr9:107659243(-) A-I      intronic
chr9:107659160(-) A-I      intronic
chr9:107650140(-) A-I      intronic
chr9:107567589(-) A-I      intronic
chr9:107659193(-) A-I      intronic
chr9:107659919(-) A-I      intronic
chr9:107660111(-) A-I      intronic
chr9:107659206(-) A-I      intronic
chr9:107624671(-) A-I      intronic
chr9:107687484(-) A-I      intronic
chr9:107649499(-) A-I      intronic
chr9:107676514(-) A-I      intronic
chr9:107649376(-) A-I      intronic
chr9:107659275(-) A-I      intronic
chr9:107660107(-) A-I      intronic
chr9:107676615(-) A-I      intronic
chr9:107659088(-) A-I      intronic
chr9:107643347(-) A-I      intronic
chr9:107623106(-) A-I      intronic
chr9:107666801(-) A-I      intronic
chr9:107659190(-) A-I      intronic
chr9:107659104(-) A-I      intronic
chr9:107643343(-) A-I      intronic
chr9:107623312(-) A-I      intronic
chr9:107659133(-) A-I      intronic
chr9:107619501(-) A-I      intronic
chr9:107659238(-) A-I      intronic
chr9:107654240(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ABCA1
chr9:107673267(-) A-I intron -    21960545

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ABCA1
chr9:107543917-107543918(-) m6A 3'UTR       27773535
chr9:107543925-107543926(-) m6A 3'UTR       27773535
chr9:107544013-107544014(-) m6A 3'UTR       27773535
chr9:107544025-107544026(-) m6A 3'UTR       27773535
chr9:107545715-107545716(-) m6A 3'UTR       24981863//27773535//27371828//22608085
chr9:107545775-107545776(-) m6A 3'UTR       27773535//22608085
chr9:107545825-107545826(-) m6A 3'UTR       27773535
chr9:107545890-107545891(-) m6A 3'UTR       27773535
chr9:107546150-107546151(-) m6A 3'UTR       24981863//26404942//27773535
chr9:107546297-107546298(-) m6A 3'UTR       24981863//26404942//27773535//22608085
chr9:107546311-107546312(-) m6A 3'UTR       24981863//26404942//27773535//22608085
chr9:107546320-107546321(-) m6A 3'UTR       24981863//26404942//27773535//22608085
chr9:107546333-107546334(-) m6A 3'UTR       24981863//26404942//27773535//22608085
chr9:107546368-107546369(-) m6A 3'UTR       24981863//26404942//27773535//22608085
chr9:107546432-107546433(-) m6A 3'UTR       24981863//26404942//27773535//22608085
chr9:107546484-107546485(-) m6A 3'UTR       24981863//26404942//27773535//27371828//22608085
chr9:107546550-107546551(-) m6A 3'UTR       24209618//24981863//26404942//27773535//27371828//22608085
chr9:107546555-107546556(-) m6A 3'UTR       24209618//24981863//26404942//27773535//27371828//22608085
chr9:107546663-107546664(-) m6A CDS       24981863//26404942//27773535//27371828//22608085
chr9:107546668-107546669(-) m6A CDS       24981863//26404942//27773535//22608085
chr9:107546686-107546687(-) m6A CDS       24981863//26404942//27773535//22608085
chr9:107546713-107546714(-) m6A CDS       24981863//27773535//22608085
chr9:107546725-107546726(-) m6A CDS       24981863//27773535//22608085
chr9:107547690-107547691(-) m6A CDS       24981863//27773535//22608085
chr9:107547707-107547708(-) m6A CDS       24981863//27773535//22608085
chr9:107547800-107547801(-) m6A CDS       24981863
chr9:107547808-107547809(-) m6A CDS       24981863
chr9:107549251-107549252(-) m6A CDS       -
chr9:107550311-107550312(-) m6A CDS       -
chr9:107555126-107555127(-) m6A CDS       27773535
chr9:107690404-107690405(-) m6A 5'UTR       24981863
chr9:107690440-107690441(-) m6A 5'UTR       24981863
chr9:107690456-107690457(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
ABCA1
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-1-3p
Interactor2: ABCA1

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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