Detail Information

Basic Information:


  VIRBase ID:  

HHID00098855

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0067985 KCNQ2
miRBase
Accession/Entrez ID		 hsa_circ_0067985 3785
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - BFNC//DEE7//EBN//EBN1//ENB1//HNSPC//KCNA11//KV7.2

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR KCNQ2
chr20:62067746(-) A-I      intronic
chr20:62082409(-) A-I      intronic
chr20:62066665(-) A-I      intronic
chr20:62079037(-) A-I      intronic
chr20:62067832(-) A-I      intronic
chr20:62068268(-) A-I      intronic
chr20:62090658(-) A-I      intronic
chr20:62069300(-) A-I      intronic
chr20:62066628(-) A-I      intronic
chr20:62068297(-) A-I      intronic
chr20:62069225(-) A-I      intronic
chr20:62069366(-) A-I      intronic
chr20:62067640(-) A-I      intronic
chr20:62082343(-) A-I      intronic
chr20:62082325(-) A-I      intronic
chr20:62067641(-) A-I      intronic
chr20:62066516(-) A-I      intronic
chr20:62072356(-) A-I      intronic
chr20:62068197(-) A-I      intronic
chr20:62068302(-) A-I      intronic
chr20:62066619(-) A-I      intronic
chr20:62066576(-) A-I      intronic
chr20:62079045(-) A-I      intronic
chr20:62072417(-) A-I      intronic
chr20:62069433(-) A-I      intronic
chr20:62068311(-) A-I      intronic
chr20:62067628(-) A-I      intronic
chr20:62079177(-) A-I      intronic
chr20:62067762(-) A-I      intronic
chr20:62067772(-) A-I      intronic
chr20:62068405(-) A-I      intronic
chr20:62068391(-) A-I      intronic
chr20:62066550(-) A-I      intronic
chr20:62068404(-) A-I      intronic
chr20:62066679(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KCNQ2
chr20:62032677-62032678(-) m6A 3'UTR//intron       -
chr20:62032751-62032752(-) m6A 3'UTR//intron       -
chr20:62032795-62032796(-) m6A 3'UTR//intron       -
chr20:62032833-62032834(-) m6A 3'UTR//intron       -
chr20:62033025-62033026(-) m6A 3'UTR//intron       -
chr20:62033147-62033148(-) m6A 3'UTR//intron       -
chr20:62033165-62033166(-) m6A 3'UTR//intron       -
chr20:62033206-62033207(-) m6A 3'UTR//intron       -
chr20:62033260-62033261(-) m6A 3'UTR//intron       -
chr20:62033319-62033320(-) m6A 3'UTR//intron       -
chr20:62033378-62033379(-) m6A 3'UTR//intron       -
chr20:62033437-62033438(-) m6A 3'UTR//intron       -
chr20:62033494-62033495(-) m6A 3'UTR//intron       -
chr20:62033500-62033501(-) m6A 3'UTR//intron       -
chr20:62033553-62033554(-) m6A 3'UTR//intron       -
chr20:62033612-62033613(-) m6A 3'UTR//intron       -
chr20:62037557-62037558(-) m6A 3'UTR//intron       25456834
chr20:62037589-62037590(-) m6A 3'UTR//intron       25456834
chr20:62037925-62037926(-) m6A 3'UTR//intron       25456834//22608085
chr20:62037976-62037977(-) m6A 3'UTR//intron       25456834//22608085
chr20:62038096-62038097(-) m6A CDS//intron       25456834//22575960
chr20:62038177-62038178(-) m6A CDS//intron       25456834//22575960//22608085
chr20:62038234-62038235(-) m6A CDS//intron       25456834//27773536//22608085
chr20:62038267-62038268(-) m6A CDS//intron       25456834//27773536//22608085
chr20:62038276-62038277(-) m6A CDS//intron       25456834//27773536//22608085
chr20:62038306-62038307(-) m6A CDS//intron       25456834//27773536//22608085
chr20:62038411-62038412(-) m6A CDS//intron       25456834//27773536
chr20:62038516-62038517(-) m6A CDS//intron       25456834//24981863//27773536
chr20:62038591-62038592(-) m6A CDS//intron       25456834//24981863
chr20:62038652-62038653(-) m6A CDS//intron       25456834
chr20:62038702-62038703(-) m6A CDS//intron       25456834
chr20:62039805-62039806(-) m6A CDS//intron       -
chr20:62071018-62071019(-) m6A CDS//exon       27773536
chr20:62071032-62071033(-) m6A CDS//exon       27773536
chr20:62103648-62103649(-) m6A CDS//exon       27773536
chr20:62103733-62103734(-) m6A CDS//exon       27773536
chr20:62103761-62103762(-) m1A CDS//exon       26863410
chr20:62103933-62103934(-) m6A 5'UTR//exon       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0067985
Exosome Blood     -
KCNQ2
Exosome Blood     -
Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0067985
Interactor2: KCNQ2

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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