Detail Information

Basic Information:


  VIRBase ID:  

HHID00098852

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0067985 CLK3
miRBase
Accession/Entrez ID		 hsa_circ_0067985 1198
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - PHCLK3//PHCLK3/152

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CLK3
chr15:74890934-74890935(+) m6A exon       25456834//24981863//22608085
chr15:74890982-74890983(+) m6A exon       25456834//24981863//22608085
chr15:74890992-74890993(+) m6A exon       25456834//24981863//22608085
chr15:74891016-74891017(+) m6A exon       25456834//24981863//22608085
chr15:74891032-74891033(+) m6A exon       25456834//24981863//22608085
chr15:74891042-74891043(+) m6A exon       25456834//24981863//22608085
chr15:74891050-74891051(+) m6A exon       25456834//24981863//22608085
chr15:74891101-74891102(+) m6A exon       25456834//24981863//22608085
chr15:74891323-74891324(+) m6A exon       24284625//24981863//22608085
chr15:74891352-74891353(+) m6A exon       24284625//24981863
chr15:74891397-74891398(+) m6A exon       24284625//24981863
chr15:74891436-74891437(+) m6A exon       24284625
chr15:74891451-74891452(+) m6A exon       24284625
chr15:74891597-74891598(+) m6A exon       22608085
chr15:74891708-74891709(+) m6A exon       22608085
chr15:74891772-74891773(+) m6A exon       22608085
chr15:74891788-74891789(+) m6A exon       22608085
chr15:74892100-74892101(+) Gm intron       -
chr15:74893955-74893956(+) m6A exon       -
chr15:74894025-74894026(+) m6A exon       24981863
chr15:74894062-74894063(+) m6A exon       24981863
chr15:74894138-74894139(+) m6A exon       24284625//25456834//24981863
chr15:74894156-74894157(+) m6A exon       24284625//25456834//24981863
chr15:74894173-74894174(+) m6A exon       24284625//25456834//24981863
chr15:74897622-74897623(+) m6A exon       -
chr15:74897627-74897628(+) m6A exon       -
chr15:74897679-74897680(+) m6A exon       -
chr15:74897740-74897741(+) m6A exon       24284625//24981863//22608085
chr15:74897765-74897766(+) m6A exon       24284625//24981863//22608085
chr15:74897827-74897828(+) m6A exon       24284625//22608085
chr15:74897849-74897850(+) m6A exon       24284625//24981863//22608085
chr15:74897860-74897861(+) m6A exon       24284625//24981863//22608085
chr15:74897910-74897911(+) m6A exon       24284625//25456834//22608085
chr15:74897922-74897923(+) m6A exon       24284625//25456834//22608085
chr15:74897952-74897953(+) m6A exon       24284625//25456834//22608085
chr15:74897979-74897980(+) m6A exon       24284625//25456834//22608085
chr15:74897994-74897995(+) m6A exon       24284625//25456834//22608085
chr15:74898002-74898003(+) m6A exon       24284625//25456834//22608085
chr15:74907792-74907793(+) m6A 5'UTR//intron       27773536
chr15:74907832-74907833(+) m6A CDS//intron       27773536
chr15:74911569-74911570(+) m6A CDS//exon//intron       -
chr15:74911574-74911575(+) m6A CDS//exon//intron       -
chr15:74911623-74911624(+) m6A CDS//exon//intron       -
chr15:74911635-74911636(+) m6A CDS//exon//intron       -
chr15:74912312-74912313(+) m6A CDS//intron       -
chr15:74912441-74912442(+) m6A 5'UTR//CDS//exon       24284625
chr15:74912451-74912452(+) m6A 5'UTR//CDS//exon       24284625
chr15:74912503-74912504(+) m6A 5'UTR//CDS//exon       24284625//24209618
chr15:74913930-74913931(+) m6A exon//intron       -
chr15:74913989-74913990(+) m6A exon//intron       -
chr15:74916102-74916103(+) m6A exon//intron       -
chr15:74916112-74916113(+) m6A exon//intron       -
chr15:74917216-74917217(+) m6A exon//intron       -
chr15:74917343-74917344(+) m6A 3'UTR//5'UTR//CDS//exon       -
chr15:74917352-74917353(+) m6A 3'UTR//5'UTR//CDS//exon       -
chr15:74918216-74918217(+) m6A 3'UTR//CDS//exon       -
chr15:74919367-74919368(+) m6A CDS//intron       -
chr15:74919403-74919404(+) m6A 3'UTR//intron       -
chr15:74919722-74919723(+) m6A 3'UTR//CDS//exon       -
chr15:74919729-74919730(+) m6A 3'UTR//CDS//exon       -
chr15:74919737-74919738(+) m6A 3'UTR//CDS//exon       -
chr15:74919766-74919767(+) m6A 3'UTR//CDS//exon       -
chr15:74919904-74919905(+) m6A 3'UTR//CDS//exon       -
chr15:74920944-74920945(+) m6A 3'UTR//CDS//exon       -
chr15:74920954-74920955(+) m6A 3'UTR//CDS//exon       -
chr15:74921416-74921417(+) m6A CDS//exon//intron       -
chr15:74921434-74921435(+) m6A CDS//exon//intron       25456834
chr15:74921447-74921448(+) m6A CDS//exon//intron       25456834//24981863
chr15:74921507-74921508(+) m6A CDS//exon//intron       25456834//24981863
chr15:74921540-74921541(+) m6A CDS//exon//intron       25456834//24981863
chr15:74921605-74921606(+) m6A 3'UTR//exon//intron       25456834//24981863
chr15:74921676-74921677(+) m6A exon//intron       25456834//24981863//22608085
chr15:74921686-74921687(+) m6A exon//intron       25456834//24981863//22608085
chr15:74921708-74921709(+) m6A exon//intron       24209618//25456834//24981863//22608085
chr15:74921714-74921715(+) m6A exon//intron       24209618//25456834//24981863//22608085
chr15:74921755-74921756(+) m6A exon//intron       24209618//25456834//24981863//22608085
chr15:74921797-74921798(+) m6A exon//intron       24209618//25456834//24981863//22608085
chr15:74921834-74921835(+) m6A exon//intron       25456834//24981863//22608085
chr15:74921872-74921873(+) m6A exon//intron       25456834//24981863//22608085
chr15:74922063-74922064(+) m6A 3'UTR//CDS//exon//intron       24284625
chr15:74922261-74922262(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr15:74922327-74922328(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr15:74922369-74922370(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr15:74927761-74927762(+) m6A 3'UTR//intron       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0067985
Exosome Blood     -
CLK3
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0067985
Interactor2: CLK3

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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