Detail Information

Basic Information:


  VIRBase ID:  

HHID00098642

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 RNF165
miRBase
Accession/Entrez ID		 hsa_circ_0002248 494470
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - Ark2C//ARKL2//RNF111L2

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RNF165
chr18:44033929(+) A-I      intronic
chr18:43945600(+) A-I      intronic
chr18:43946220(+) A-I      intronic
chr18:44024478(+) A-I      intronic
chr18:44031725(+) A-I      intronic
chr18:44033965(+) A-I      intronic
chr18:44031552(+) A-I      intronic
chr18:44033973(+) A-I      intronic
chr18:43945491(+) A-I      intronic
chr18:44032304(+) A-I      intronic
chr18:44032342(+) A-I      intronic
chr18:44032266(+) A-I      intronic
chr18:44021596(+) A-I      intronic
chr18:43956913(+) A-I      intronic
chr18:44033996(+) A-I      intronic
chr18:44021049(+) A-I      intronic
chr18:44035624(+) A-I      intronic
chr18:44035542(+) A-I      intronic
chr18:44033995(+) A-I      intronic
chr18:44033894(+) A-I      intronic
chr18:44035733(+) A-I      intronic
chr18:44026536(+) A-I      intronic
chr18:44020053(+) A-I      intronic
chr18:44031683(+) A-I      intronic
chr18:44031688(+) A-I      intronic
chr18:44024698(+) A-I      intronic
chr18:43945541(+) A-I      intronic
chr18:44035710(+) A-I      intronic
chr18:43982673(+) A-I      intronic
chr18:44033962(+) A-I      intronic
chr18:44033866(+) A-I      intronic
chr18:44021098(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RNF165
chr18:44036522-44036523(+) m6A 3'UTR//CDS       25456834
chr18:44036567-44036568(+) m6A 3'UTR//CDS       25456834//22608085
chr18:44036575-44036576(+) m6A 3'UTR//CDS       25456834//22608085
chr18:44036618-44036619(+) m6A 3'UTR       25456834//24981863//22608085
chr18:44036670-44036671(+) m6A 3'UTR       24209618//25456834//24981863//22608085
chr18:44036777-44036778(+) m6A 3'UTR       25456834
chr18:44036886-44036887(+) m6A 3'UTR       25456834
chr18:44036979-44036980(+) m6A 3'UTR       -
chr18:44039386-44039387(+) m6A 3'UTR       25456834
chr18:44039415-44039416(+) m6A 3'UTR       25456834
chr18:44039445-44039446(+) m6A 3'UTR       25456834
chr18:44040014-44040015(+) m6A 3'UTR       25456834
chr18:44040059-44040060(+) m6A 3'UTR       25456834
chr18:44040128-44040129(+) m6A 3'UTR       25456834
chr18:44041528-44041529(+) m6A 3'UTR       -
chr18:44041595-44041596(+) m6A 3'UTR       24981863
chr18:44041600-44041601(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
RNF165
Exosome Blood     -
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: RNF165

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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