Detail Information

Basic Information:


  VIRBase ID:  

HHID00098641

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 MXRA7
miRBase
Accession/Entrez ID		 hsa_circ_0002248 439921
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - -

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MXRA7
chr17:74686927(-) A-I      intronic
chr17:74703508(-) A-I      intronic
chr17:74703665(-) A-I      intronic
chr17:74673192(-) A-I      3'UTR
chr17:74698481(-) A-I      intronic
chr17:74698497(-) A-I      intronic
chr17:74692055(-) A-I      intronic
chr17:74692069(-) A-I      intronic
chr17:74692053(-) A-I      intronic
chr17:74688382(-) A-I      intronic
chr17:74698478(-) A-I      intronic
chr17:74692049(-) A-I      intronic
chr17:74685969(-) A-I      intronic
chr17:74685970(-) A-I      intronic
chr17:74685971(-) A-I      intronic
chr17:74686918(-) A-I      intronic
chr17:74692478(-) A-I      intronic
chr17:74692535(-) A-I      intronic
chr17:74690793(-) A-I      intronic
chr17:74689405(-) A-I      intronic
chr17:74689410(-) A-I      intronic
chr17:74689464(-) A-I      intronic
chr17:74689484(-) A-I      intronic
chr17:74690788(-) A-I      intronic
chr17:74690765(-) A-I      intronic
chr17:74689840(-) A-I      intronic
chr17:74689828(-) A-I      intronic
chr17:74689702(-) A-I      intronic
chr17:74689495(-) A-I      intronic
chr17:74690671(-) A-I      intronic
chr17:74692534(-) A-I      intronic
chr17:74690841(-) A-I      intronic
chr17:74690837(-) A-I      intronic
chr17:74690836(-) A-I      intronic
chr17:74690835(-) A-I      intronic
chr17:74690806(-) A-I      intronic
chr17:74689402(-) A-I      intronic
chr17:74692508(-) A-I      intronic
chr17:74692399(-) A-I      intronic
chr17:74692077(-) A-I      intronic
chr17:74692065(-) A-I      intronic
chr17:74692562(-) A-I      intronic
chr17:74692033(-) A-I      intronic
chr17:74691983(-) A-I      intronic
chr17:74691074(-) A-I      intronic
chr17:74690856(-) A-I      intronic
chr17:74690852(-) A-I      intronic
chr17:74698785(-) A-I      intronic
chr17:74688614(-) A-I      intronic
chr17:74698546(-) A-I      intronic
chr17:74698540(-) A-I      intronic
chr17:74698538(-) A-I      intronic
chr17:74698466(-) A-I      intronic
chr17:74698458(-) A-I      intronic
chr17:74696326(-) A-I      intronic
chr17:74696222(-) A-I      intronic
chr17:74688608(-) A-I      intronic
chr17:74688607(-) A-I      intronic
chr17:74688508(-) A-I      intronic
chr17:74688412(-) A-I      intronic
chr17:74696217(-) A-I      intronic
chr17:74688253(-) A-I      intronic
chr17:74688215(-) A-I      intronic
chr17:74686934(-) A-I      intronic
chr17:74686922(-) A-I      intronic
chr17:74686913(-) A-I      intronic
chr17:74686905(-) A-I      intronic
chr17:74695441(-) A-I      intronic
chr17:74686887(-) A-I      intronic
chr17:74686562(-) A-I      intronic
chr17:74686540(-) A-I      intronic
chr17:74685877(-) A-I      intronic
chr17:74685441(-) A-I      intronic
chr17:74685388(-) A-I      intronic
chr17:74685350(-) A-I      intronic
chr17:74695088(-) A-I      intronic
chr17:74695084(-) A-I      intronic
chr17:74694953(-) A-I      intronic
chr17:74694913(-) A-I      intronic
chr17:74694902(-) A-I      intronic
chr17:74694881(-) A-I      intronic
chr17:74694835(-) A-I      intronic
chr17:74686901(-) A-I      intronic
chr17:74685283(-) A-I      intronic
chr17:74688404(-) A-I      intronic
chr17:74672745(-) A-I      3'UTR
chr17:74673118(-) A-I      3'UTR
chr17:74672883(-) A-I      3'UTR
chr17:74673207(-) A-I      3'UTR
chr17:74673203(-) A-I      3'UTR
chr17:74672857(-) A-I      3'UTR
chr17:74673336(-) A-I      3'UTR
chr17:74673183(-) A-I      3'UTR
chr17:74672763(-) A-I      3'UTR
chr17:74672665(-) A-I      3'UTR
chr17:74672696(-) A-I      3'UTR
chr17:74673305(-) A-I      3'UTR
chr17:74672762(-) A-I      3'UTR
chr17:74673274(-) A-I      3'UTR
chr17:74672682(-) A-I      3'UTR
chr17:74673145(-) A-I      3'UTR
chr17:74673239(-) A-I      3'UTR
chr17:74673130(-) A-I      3'UTR
chr17:74672679(-) A-I      3'UTR
chr17:74673265(-) A-I      3'UTR
chr17:74672588(-) A-I      3'UTR
chr17:74673212(-) A-I      3'UTR
chr17:74673226(-) A-I      3'UTR
chr17:74673225(-) A-I      3'UTR
chr17:74673218(-) A-I      3'UTR
chr17:74672736(-) A-I      3'UTR
chr17:74672733(-) A-I      3'UTR
chr17:74672723(-) A-I      3'UTR
chr17:74672701(-) A-I      3'UTR
chr17:74690751(-) A-I      intronic
chr17:74685863(-) A-I      intronic
chr17:74685378(-) A-I      intronic
chr17:74690668(-) A-I      intronic
chr17:74685421(-) A-I      intronic
chr17:74696232(-) A-I      intronic
chr17:74685300(-) A-I      intronic
chr17:74685832(-) A-I      intronic
chr17:74685878(-) A-I      intronic
chr17:74689785(-) A-I      intronic
chr17:74688432(-) A-I      intronic
chr17:74695404(-) A-I      intronic
chr17:74694916(-) A-I      intronic
chr17:74703512(-) A-I      intronic
chr17:74690983(-) A-I      intronic
chr17:74688214(-) A-I      intronic
chr17:74692354(-) A-I      intronic
chr17:74686047(-) A-I      intronic
chr17:74694969(-) A-I      intronic
chr17:74689406(-) A-I      intronic
chr17:74691060(-) A-I      intronic
chr17:74690740(-) A-I      intronic
chr17:74699187(-) A-I      intronic
chr17:74685814(-) A-I      intronic
chr17:74700704(-) A-I      intronic
chr17:74694942(-) A-I      intronic
chr17:74685309(-) A-I      intronic
chr17:74694982(-) A-I      intronic
chr17:74686574(-) A-I      intronic
chr17:74700684(-) A-I      intronic
chr17:74685448(-) A-I      intronic
chr17:74695427(-) A-I      intronic
chr17:74695326(-) A-I      intronic
chr17:74685341(-) A-I      intronic
chr17:74695292(-) A-I      intronic
chr17:74694943(-) A-I      intronic
chr17:74688599(-) A-I      intronic
chr17:74689295(-) A-I      intronic
chr17:74673242(-) A-I      3'UTR
chr17:74685264(-) A-I      intronic
chr17:74690757(-) A-I      intronic
chr17:74685470(-) A-I      intronic
chr17:74690828(-) A-I      intronic
chr17:74685310(-) A-I      intronic
chr17:74695406(-) A-I      intronic
chr17:74685257(-) A-I      intronic
chr17:74685923(-) A-I      intronic
chr17:74695407(-) A-I      intronic
chr17:74685945(-) A-I      intronic
chr17:74673292(-) A-I      3'UTR
chr17:74673246(-) A-I      3'UTR
chr17:74695410(-) A-I      intronic
chr17:74673360(-) A-I      3'UTR
chr17:74692175(-) A-I      intronic
chr17:74685464(-) A-I      intronic
chr17:74700815(-) A-I      intronic
chr17:74694901(-) A-I      intronic
chr17:74698790(-) A-I      intronic
chr17:74699167(-) A-I      intronic
chr17:74691982(-) A-I      intronic
chr17:74688281(-) A-I      intronic
chr17:74673262(-) A-I      3'UTR
chr17:74685337(-) A-I      intronic
chr17:74685897(-) A-I      intronic
chr17:74698858(-) A-I      intronic
chr17:74672594(-) A-I      3'UTR
chr17:74686011(-) A-I      intronic
chr17:74673234(-) A-I      3'UTR
chr17:74695352(-) A-I      intronic
chr17:74700059(-) A-I      intronic
chr17:74690779(-) A-I      intronic
chr17:74688237(-) A-I      intronic
chr17:74692009(-) A-I      intronic
chr17:74686091(-) A-I      intronic
chr17:74688338(-) A-I      intronic
chr17:74685442(-) A-I      intronic
chr17:74685859(-) A-I      intronic
chr17:74685981(-) A-I      intronic
chr17:74698407(-) A-I      intronic
chr17:74673209(-) A-I      3'UTR
chr17:74695405(-) A-I      intronic
chr17:74691939(-) A-I      intronic
chr17:74685872(-) A-I      intronic
chr17:74685270(-) A-I      intronic
chr17:74685348(-) A-I      intronic
chr17:74695325(-) A-I      intronic
chr17:74696248(-) A-I      intronic
chr17:74686054(-) A-I      intronic
chr17:74688396(-) A-I      intronic
chr17:74690887(-) A-I      intronic
chr17:74688351(-) A-I      intronic
chr17:74686024(-) A-I      intronic
chr17:74690914(-) A-I      intronic
chr17:74689293(-) A-I      intronic
chr17:74685248(-) A-I      intronic
chr17:74689387(-) A-I      intronic
chr17:74685363(-) A-I      intronic
chr17:74686010(-) A-I      intronic
chr17:74689805(-) A-I      intronic
chr17:74690735(-) A-I      intronic
chr17:74700675(-) A-I      intronic
chr17:74685932(-) A-I      intronic
chr17:74686895(-) A-I      intronic
chr17:74698366(-) A-I      intronic
chr17:74699501(-) A-I      intronic
chr17:74686898(-) A-I      intronic
chr17:74698812(-) A-I      intronic
chr17:74689384(-) A-I      intronic
chr17:74689463(-) A-I      intronic
chr17:74685402(-) A-I      intronic
chr17:74695076(-) A-I      intronic
chr17:74695416(-) A-I      intronic
chr17:74685944(-) A-I      intronic
chr17:74679403(-) A-I      intronic
chr17:74689223(-) A-I      intronic
chr17:74695431(-) A-I      intronic
chr17:74685304(-) A-I      intronic
chr17:74692094(-) A-I      intronic
chr17:74703471(-) A-I      intronic
chr17:74690832(-) A-I      intronic
chr17:74695455(-) A-I      intronic
chr17:74689885(-) A-I      intronic
chr17:74699607(-) A-I      intronic
chr17:74699458(-) A-I      intronic
chr17:74698507(-) A-I      intronic
chr17:74688403(-) A-I      intronic
chr17:74689693(-) A-I      intronic
chr17:74692012(-) A-I      intronic
chr17:74688433(-) A-I      intronic
chr17:74685277(-) A-I      intronic
chr17:74685357(-) A-I      intronic
chr17:74695501(-) A-I      intronic
chr17:74695034(-) A-I      intronic
chr17:74696223(-) A-I      intronic
chr17:74690827(-) A-I      intronic
chr17:74688228(-) A-I      intronic
chr17:74671903(-) A-I      3'UTR
chr17:74673291(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED MXRA7
chr17:74671903(-) A-I exon 3'UTR    15342557
chr17:74685248(-) A-I intron -    15342557
chr17:74685257(-) A-I intron -    15342557
chr17:74685264(-) A-I intron -    15342557
chr17:74685270(-) A-I intron -    15342557
chr17:74685277(-) A-I intron -    15342557
chr17:74685300(-) A-I intron -    15342557
chr17:74685309(-) A-I intron -    15342557
chr17:74685310(-) A-I intron -    15342557
chr17:74685348(-) A-I intron -    15342557
chr17:74685357(-) A-I intron -    15342557
chr17:74685363(-) A-I intron -    15342557
chr17:74685378(-) A-I intron -    15342557
chr17:74685402(-) A-I intron -    15342557
chr17:74685421(-) A-I intron -    15342557
chr17:74685442(-) A-I intron -    15342557
chr17:74685464(-) A-I intron -    15342557
chr17:74685470(-) A-I intron -    15342557
chr17:74685863(-) A-I intron -    15342557
chr17:74685872(-) A-I intron -    15342557
chr17:74685878(-) A-I intron -    15342557
chr17:74685897(-) A-I intron -    15342557
chr17:74685923(-) A-I intron -    15342557
chr17:74685932(-) A-I intron -    15342557
chr17:74685944(-) A-I intron -    15342557
chr17:74685945(-) A-I intron -    15342557
chr17:74685981(-) A-I intron -    15342557
chr17:74686010(-) A-I intron -    15342557
chr17:74686011(-) A-I intron -    15342557
chr17:74686024(-) A-I intron -    15342557
chr17:74686047(-) A-I intron -    15342557
chr17:74686054(-) A-I intron -    15342557
chr17:74686091(-) A-I intron -    15342557
chr17:74673246(-) A-I exon 3'UTR    21960545
chr17:74673291(-) A-I exon 3'UTR    21960545
chr17:74673292(-) A-I exon 3'UTR    21960545
chr17:74672619(-) A-I exon 3'UTR    21960545

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MXRA7
chr17:74668654-74668655(-) m6A 3'UTR       22608085
chr17:74668707-74668708(-) m6A 3'UTR       25456834//24981863//22608085
chr17:74668826-74668827(-) m6A 3'UTR       24981863//22608085
chr17:74668948-74668949(-) m6A 3'UTR       22608085
chr17:74669026-74669027(-) m6A 3'UTR       22608085
chr17:74669060-74669061(-) m6A 3'UTR       22608085
chr17:74669183-74669184(-) m6A 3'UTR       24209618//25456834//22608085
chr17:74669243-74669244(-) m6A 3'UTR       25456834//24981863//22608085
chr17:74669529-74669530(-) m6A 3'UTR       22608085
chr17:74669583-74669584(-) m6A 3'UTR       22608085
chr17:74669848-74669849(-) m6A 3'UTR       27773535
chr17:74669890-74669891(-) m6A 3'UTR       24981863//27773535
chr17:74669928-74669929(-) m6A 3'UTR       24981863//27773535
chr17:74670059-74670060(-) m6A 3'UTR       24981863//27773535
chr17:74670104-74670105(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr17:74670155-74670156(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr17:74670199-74670200(-) m6A 3'UTR       24981863//22608085
chr17:74670227-74670228(-) m6A 3'UTR       24981863//27773535//22608085
chr17:74670269-74670270(-) m6A 3'UTR       24981863//27773535//22608085
chr17:74670341-74670342(-) m6A 3'UTR       24981863//27773535
chr17:74670367-74670368(-) m6A 3'UTR       24981863//27773535
chr17:74670408-74670409(-) m6A 3'UTR       24981863
chr17:74670541-74670542(-) m6A 3'UTR       24981863
chr17:74670554-74670555(-) m6A 3'UTR       24981863
chr17:74670693-74670694(-) m6A 3'UTR       -
chr17:74670808-74670809(-) m6A 3'UTR       24981863//22608085
chr17:74670827-74670828(-) m6A 3'UTR       24981863//22608085
chr17:74670834-74670835(-) m6A 3'UTR       24981863//22608085
chr17:74670925-74670926(-) m6A 3'UTR       24981863
chr17:74671026-74671027(-) m6A 3'UTR       24981863
chr17:74671109-74671110(-) m6A 3'UTR       24981863
chr17:74671144-74671145(-) m6A 3'UTR       24981863//22608085
chr17:74671150-74671151(-) m6A 3'UTR       24981863//22608085
chr17:74671171-74671172(-) m6A 3'UTR       24981863//22608085
chr17:74671230-74671231(-) m6A 3'UTR       24981863
chr17:74673204-74673205(-) m6A 3'UTR       24209618
chr17:74673668-74673669(-) m6A 3'UTR       24209618//27371828
chr17:74673739-74673740(-) m6A CDS       24209618//24981863//27773535//27371828
chr17:74673771-74673772(-) m6A CDS       24209618//24981863//27773535//27371828
chr17:74675670-74675671(-) m6A 3'UTR//intron       24209618//24981863//27773535//27371828
chr17:74676372-74676373(-) m6A 3'UTR//intron       24284625
chr17:74676443-74676444(-) m6A 3'UTR//intron       24284625
chr17:74676513-74676514(-) m6A 3'UTR//intron       24284625//22608085
chr17:74676530-74676531(-) m6A 3'UTR//intron       24284625//24981863//22608085
chr17:74676540-74676541(-) m6A 3'UTR//intron       24284625//24981863//22608085
chr17:74676603-74676604(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr17:74676643-74676644(-) m6A 3'UTR//intron       24284625//24981863//22608085
chr17:74676667-74676668(-) m6A 3'UTR//intron       24284625//24981863//22608085
chr17:74676674-74676675(-) m6A 3'UTR//intron       24284625//24981863//22608085
chr17:74676765-74676766(-) m6A 3'UTR//intron       24284625//24981863//22608085
chr17:74676795-74676796(-) m6A 3'UTR//intron       24284625//24981863//22608085
chr17:74676808-74676809(-) m6A 3'UTR//intron       24284625//24981863//22608085
chr17:74676875-74676876(-) m6A 3'UTR//intron       24284625//24981863
chr17:74681201-74681202(-) m6A 5'UTR//CDS       24284625//24209618//24981863//27773535//27371828
chr17:74684244-74684245(-) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536
chr17:74684357-74684358(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536
chr17:74705661-74705662(-) m6A 5'UTR//intron       24981863
chr17:74706764-74706765(-) m6A CDS       24981863
chr17:74706899-74706900(-) m6A CDS       24209618

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
MXRA7
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: MXRA7

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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