Detail Information

Basic Information:


  VIRBase ID:  

HHID00098637

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 SLC25A35
miRBase
Accession/Entrez ID		 hsa_circ_0002248 399512
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - -

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SLC25A35
chr17:8195595(-) A-I      intronic
chr17:8191659(-) A-I      3'UTR
chr17:8191489(-) A-I      3'UTR
chr17:8191509(-) A-I      3'UTR
chr17:8191690(-) A-I      3'UTR
chr17:8195594(-) A-I      intronic
chr17:8191676(-) A-I      3'UTR
chr17:8191534(-) A-I      3'UTR
chr17:8196967(-) A-I      intronic
chr17:8195117(-) A-I      intronic
chr17:8195417(-) A-I      intronic
chr17:8195565(-) A-I      intronic
chr17:8195554(-) A-I      intronic
chr17:8191549(-) A-I      3'UTR
chr17:8191677(-) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SLC25A35
chr17:8191422-8191423(-) m6A 3'UTR       24284625
chr17:8191538-8191539(-) m6A 3'UTR//exon       24284625//24981863
chr17:8191546-8191547(-) m6A 3'UTR//exon       24284625//24981863
chr17:8191680-8191681(-) m6A 3'UTR//exon       -
chr17:8191931-8191932(-) m6A 3'UTR//intron       24981863
chr17:8192133-8192134(-) m6A 3'UTR//intron       24284625//24981863
chr17:8192545-8192546(-) m6A 3'UTR//intron       -
chr17:8192619-8192620(-) m6A 3'UTR//intron       27371828
chr17:8192634-8192635(-) m6A 3'UTR//intron       27371828
chr17:8192647-8192648(-) m6A 3'UTR//intron       27371828
chr17:8192944-8192945(-) m6A 3'UTR//CDS       24284625
chr17:8193214-8193215(-) m6A 3'UTR//CDS       24284625//25456834//24981863//22608085
chr17:8193244-8193245(-) m6A CDS       24284625//25456834//24981863//22608085
chr17:8193444-8193445(-) m6A 3'UTR//intron       25456834//24981863//27773535//22608085
chr17:8193466-8193467(-) m6A 3'UTR//intron       24981863//27773535
chr17:8193484-8193485(-) m6A 3'UTR//intron       24981863//27773535
chr17:8193499-8193500(-) m6A 3'UTR//intron       27773535
chr17:8193628-8193629(-) m6A 3'UTR//intron       27773535
chr17:8193713-8193714(-) m6A 3'UTR//intron       27773535
chr17:8193832-8193833(-) m6A CDS//intron       24284625//24981863//27773535
chr17:8193859-8193860(-) m6A CDS//intron       24284625//24981863//27773535
chr17:8193947-8193948(-) m6A CDS//intron       24284625//27773535
chr17:8193956-8193957(-) m6A CDS//intron       24284625//27773535
chr17:8198029-8198030(-) m6A CDS       -
chr17:8198052-8198053(-) m6A CDS       24981863
chr17:8198120-8198121(-) m6A CDS       24284625//24981863//27773535
chr17:8198215-8198216(-) m6A 5'UTR       24284625//24981863//27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
SLC25A35
Chromatin K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: SLC25A35

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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