Detail Information

Basic Information:


  VIRBase ID:  

HHID00098633

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 SFT2D2
miRBase
Accession/Entrez ID		 hsa_circ_0002248 375035
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - dJ747L4.C1.2//UNQ512

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SFT2D2
chr1:168209989(+) A-I      intronic
chr1:168209897(+) A-I      intronic
chr1:168209990(+) A-I      intronic
chr1:168209896(+) A-I      intronic
chr1:168209948(+) A-I      intronic
chr1:168209964(+) A-I      intronic
chr1:168209991(+) A-I      intronic
chr1:168210515(+) A-I      intronic
chr1:168209889(+) A-I      intronic
chr1:168209230(+) A-I      intronic
chr1:168209260(+) A-I      intronic
chr1:168196157(+) A-I      intronic
chr1:168209894(+) A-I      intronic
chr1:168209256(+) A-I      intronic
chr1:168209158(+) A-I      intronic
chr1:168196184(+) A-I      intronic
chr1:168196170(+) A-I      intronic
chr1:168196158(+) A-I      intronic
chr1:168209254(+) A-I      intronic
chr1:168207645(+) A-I      intronic
chr1:168209998(+) A-I      intronic
chr1:168209259(+) A-I      intronic
chr1:168209253(+) A-I      intronic
chr1:168209994(+) A-I      intronic
chr1:168209992(+) A-I      intronic
chr1:168210000(+) A-I      intronic
chr1:168209427(+) A-I      intronic
chr1:168209884(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SFT2D2
chr1:168196066(+) C-T intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SFT2D2
chr1:168195306-168195307(+) m6A 5'UTR//exon       24284625//25456834//24981863//22608085
chr1:168195321-168195322(+) m6A CDS//exon       24284625//25456834//24981863//22608085
chr1:168195332-168195333(+) m1A CDS//exon       26863196
chr1:168195351-168195352(+) m6A CDS//exon       24284625//25456834//24981863//22608085
chr1:168195360-168195361(+) m6A CDS//exon       24284625//25456834//24981863//22608085
chr1:168205963-168205964(+) m6A CDS//exon       24284625
chr1:168211817-168211818(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr1:168211831-168211832(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr1:168211854-168211855(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr1:168211869-168211870(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr1:168211913-168211914(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr1:168211954-168211955(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr1:168212070-168212071(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr1:168212164-168212165(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr1:168212255-168212256(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr1:168212274-168212275(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr1:168214406-168214407(+) m6A 3'UTR       24981863
chr1:168214442-168214443(+) m6A 3'UTR       24981863
chr1:168221522-168221523(+) m6A 3'UTR       24981863//26404942
chr1:168221532-168221533(+) m6A 3'UTR       24981863//26404942
chr1:168221543-168221544(+) m6A 3'UTR       24981863//26404942
chr1:168221567-168221568(+) m6A 3'UTR       24284625//24981863//26404942
chr1:168221580-168221581(+) m6A 3'UTR       24284625//24981863//26404942
chr1:168221611-168221612(+) m6A 3'UTR       24284625//24981863//26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
SFT2D2
Cytosol K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: SFT2D2

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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