Detail Information

Basic Information:


  VIRBase ID:  

HHID00098628

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 FFAR4
miRBase
Accession/Entrez ID		 hsa_circ_0002248 338557
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - BMIQ10//GPR120//GPR129//GT01//O3FAR1//PGR4

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR FFAR4
chr10:95344727(+) A-I      intronic
chr10:95343052(+) A-I      intronic
chr10:95347571(+) A-I      3'UTR
chr10:95348499(+) A-I      3'UTR
chr10:95337508(+) A-I      intronic
chr10:95348543(+) A-I      3'UTR
chr10:95337516(+) A-I      intronic
chr10:95348582(+) A-I      3'UTR
chr10:95348521(+) A-I      3'UTR
chr10:95345633(+) A-I      intronic
chr10:95348507(+) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase FFAR4
chr10:95326450-95326451(+) m6A 5'UTR       24981863
chr10:95347163-95347164(+) m6A CDS//intron       24981863
chr10:95347229-95347230(+) m6A CDS//intron       24981863
chr10:95347322-95347323(+) m6A CDS//intron       24981863
chr10:95347419-95347420(+) m6A 3'UTR//intron       24981863
chr10:95347472-95347473(+) m6A 3'UTR//intron       24981863
chr10:95347486-95347487(+) m6A 3'UTR//intron       24981863
chr10:95348719-95348720(+) m6A 3'UTR//intron       24981863
chr10:95348794-95348795(+) m6A 3'UTR//intron       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
FFAR4
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: FFAR4

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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