Detail Information

Basic Information:


  VIRBase ID:  

HHID00098622

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 EMC10
miRBase
Accession/Entrez ID		 hsa_circ_0002248 284361
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - C19orf63//HSM1//HSS1

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase EMC10
chr19:50979793-50979794(+) m1A 5'UTR       26863196//26863410
chr19:50979900-50979901(+) m6A CDS//intron       25456834//24981863//22575960
chr19:50980436-50980437(+) m6A CDS//intron       24981863
chr19:50980460-50980461(+) m6A CDS//intron       24981863
chr19:50983865-50983866(+) m6A 3'UTR//CDS       22575960
chr19:50983964-50983965(+) m6A 3'UTR//CDS       -
chr19:50984179-50984180(+) m6A 3'UTR//CDS       -
chr19:50984199-50984200(+) m6A 3'UTR//CDS       -
chr19:50985694-50985695(+) m6A 3'UTR//CDS       -
chr19:50985860-50985861(+) m6A 3'UTR//CDS       24284625
chr19:50986143-50986144(+) m6A 3'UTR       -
chr19:50986191-50986192(+) m6A 3'UTR       26404942
chr19:50986219-50986220(+) m6A 3'UTR       26404942
chr19:50986224-50986225(+) m6A 3'UTR       26404942
chr19:50986252-50986253(+) m6A 3'UTR       -
chr19:50986266-50986267(+) m6A 3'UTR       -
chr19:50986306-50986307(+) m6A 3'UTR       24284625
chr19:50986372-50986373(+) m6A 3'UTR       24284625//24981863
chr19:50986513-50986514(+) m6A 3'UTR       27773535
chr19:50986725-50986726(+) Cm 3'UTR       -
chr19:50991043-50991044(+) m6A 3'UTR       -
chr19:50991072-50991073(+) m6A 3'UTR       -
chr19:50991083-50991084(+) m6A 3'UTR       -
chr19:50991091-50991092(+) m6A 3'UTR       -
chr19:50991115-50991116(+) m6A 3'UTR       -
chr19:50991130-50991131(+) m6A 3'UTR       -
chr19:50991207-50991208(+) m6A 3'UTR       -
chr19:50991923-50991924(+) m6A 3'UTR       -
chr19:50991950-50991951(+) m6A 3'UTR       -
chr19:50991958-50991959(+) m6A 3'UTR       -
chr19:50992042-50992043(+) m6A 3'UTR       -
chr19:50992089-50992090(+) m6A 3'UTR       -
chr19:50992134-50992135(+) m6A 3'UTR       -
chr19:50992151-50992152(+) m6A 3'UTR       -
chr19:50992190-50992191(+) m1A 3'UTR       26863196
chr19:50992211-50992212(+) m6A 3'UTR       -
chr19:50992228-50992229(+) m6A 3'UTR       -
chr19:50992235-50992236(+) m6A 3'UTR       -
chr19:50992386-50992387(+) m6A 3'UTR       -
chr19:50992402-50992403(+) m1A 3'UTR       26863196
chr19:50992960-50992961(+) m6A 3'UTR       -
chr19:50992981-50992982(+) m6A 3'UTR       -
chr19:50993058-50993059(+) m6A 3'UTR       -
chr19:50993065-50993066(+) m6A 3'UTR       -
chr19:50993070-50993071(+) m6A 3'UTR       -
chr19:50993075-50993076(+) m6A 3'UTR       -
chr19:50993081-50993082(+) m6A 3'UTR       -
chr19:50993105-50993106(+) m6A 3'UTR       -
chr19:50993795-50993796(+) m6A 3'UTR       -
chr19:50993803-50993804(+) m6A 3'UTR       -
chr19:50993815-50993816(+) m6A 3'UTR       -
chr19:50993835-50993836(+) m6A 3'UTR       -
chr19:50993872-50993873(+) m6A 3'UTR       -
chr19:50993911-50993912(+) m6A 3'UTR       -
chr19:50994000-50994001(+) m6A 3'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
EMC10
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: EMC10

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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