Detail Information

Basic Information:


  VIRBase ID:  

HHID00098621

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 TSEN54
miRBase
Accession/Entrez ID		 hsa_circ_0002248 283989
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - PCH2A//PCH4//PCH5//sen54//SEN54L

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TSEN54
chr17:73516874(+) A-I      intronic
chr17:73515769(+) A-I      intronic
chr17:73516882(+) A-I      intronic
chr17:73516926(+) A-I      intronic
chr17:73515705(+) A-I      intronic
chr17:73515743(+) A-I      intronic
chr17:73515744(+) A-I      intronic
chr17:73515747(+) A-I      intronic
chr17:73515761(+) A-I      intronic
chr17:73516775(+) A-I      intronic
chr17:73516965(+) A-I      intronic
chr17:73516986(+) A-I      intronic
chr17:73516569(+) A-I      intronic
chr17:73516859(+) A-I      intronic
chr17:73515834(+) A-I      intronic
chr17:73516782(+) A-I      intronic
chr17:73516441(+) A-I      intronic
chr17:73515906(+) A-I      intronic
chr17:73515916(+) A-I      intronic
chr17:73516447(+) A-I      intronic
chr17:73515675(+) A-I      intronic
chr17:73516781(+) A-I      intronic
chr17:73516617(+) A-I      intronic
chr17:73515928(+) A-I      intronic
chr17:73516914(+) A-I      intronic
chr17:73516475(+) A-I      intronic
chr17:73515915(+) A-I      intronic
chr17:73516795(+) A-I      intronic
chr17:73516888(+) A-I      intronic
chr17:73516987(+) A-I      intronic
chr17:73515713(+) A-I      intronic
chr17:73516455(+) A-I      intronic
chr17:73515863(+) A-I      intronic
chr17:73515785(+) A-I      intronic
chr17:73515934(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TSEN54
chr17:73515906(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TSEN54
chr17:73512177-73512178(+) m6A 5'UTR       25456834//24981863
chr17:73512291-73512292(+) m6A 5'UTR       25456834//24981863
chr17:73513057-73513058(+) m6A exon//intron       24284625
chr17:73513067-73513068(+) m6A exon//intron       24284625
chr17:73513172-73513173(+) m6A CDS//intron       24284625
chr17:73513179-73513180(+) m6A CDS//intron       24284625
chr17:73517814-73517815(+) m6A 3'UTR//CDS//intron       24284625//25456834//24981863
chr17:73517893-73517894(+) m6A 3'UTR//CDS//intron       24284625//25456834//24981863
chr17:73518051-73518052(+) m6A 3'UTR//CDS//intron       24284625//25456834//24981863//22608085
chr17:73518087-73518088(+) m6A 3'UTR//CDS       24284625//25456834//24981863//22608085
chr17:73518155-73518156(+) m6A 3'UTR//CDS       24284625//25456834//22575960//22608085
chr17:73518186-73518187(+) m6A 3'UTR//CDS       24284625//25456834//22575960//22608085
chr17:73518470-73518471(+) m6A CDS//intron       24284625//25456834//24981863//22575960//22608085
chr17:73518492-73518493(+) m6A CDS//intron       24284625//25456834//24981863//22575960//22608085
chr17:73518538-73518539(+) m6A CDS//intron       24284625//25456834//24981863//22575960//22608085
chr17:73520362-73520363(+) m6A CDS//exon       24284625
chr17:73520461-73520462(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085
chr17:73520531-73520532(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr17:73520537-73520538(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr17:73520554-73520555(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr17:73520581-73520582(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr17:73520649-73520650(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr17:73520696-73520697(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr17:73520703-73520704(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr17:73520717-73520718(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr17:73520743-73520744(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
TSEN54
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: TSEN54

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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