Detail Information

Basic Information:


  VIRBase ID:  

HHID00098617

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 MPV17L
miRBase
Accession/Entrez ID		 hsa_circ_0002248 255027
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - M-LPH//MLPH1//MLPH2//MPV17L1

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MPV17L
chr16:15497296(+) A-I      intronic
chr16:15502605(+) A-I      3'UTR
chr16:15502876(+) A-I      3'UTR
chr16:15496685(+) A-I      intronic
chr16:15496675(+) A-I      intronic
chr16:15496665(+) A-I      intronic
chr16:15502601(+) A-I      3'UTR
chr16:15497349(+) A-I      intronic
chr16:15497310(+) A-I      intronic
chr16:15502615(+) A-I      3'UTR
chr16:15502768(+) A-I      3'UTR
chr16:15502805(+) A-I      3'UTR
chr16:15497210(+) A-I      intronic
chr16:15501531(+) A-I      intronic
chr16:15501499(+) A-I      intronic
chr16:15501479(+) A-I      intronic
chr16:15500715(+) A-I      intronic
chr16:15500668(+) A-I      intronic
chr16:15500582(+) A-I      intronic
chr16:15500573(+) A-I      intronic
chr16:15500568(+) A-I      intronic
chr16:15500002(+) A-I      intronic
chr16:15499362(+) A-I      intronic
chr16:15497268(+) A-I      intronic
chr16:15497208(+) A-I      intronic
chr16:15497111(+) A-I      intronic
chr16:15495570(+) A-I      intronic
chr16:15495562(+) A-I      intronic
chr16:15493332(+) A-I      intronic
chr16:15492183(+) A-I      intronic
chr16:15502881(+) A-I      3'UTR
chr16:15502765(+) A-I      3'UTR
chr16:15503038(+) A-I      3'UTR
chr16:15502721(+) A-I      3'UTR
chr16:15502663(+) A-I      3'UTR
chr16:15502521(+) A-I      3'UTR
chr16:15503113(+) A-I      3'UTR
chr16:15503105(+) A-I      3'UTR
chr16:15503019(+) A-I      3'UTR
chr16:15502960(+) A-I      3'UTR
chr16:15502898(+) A-I      3'UTR
chr16:15503000(+) A-I      3'UTR
chr16:15497470(+) A-I      intronic
chr16:15497519(+) A-I      intronic
chr16:15501345(+) A-I      intronic
chr16:15493801(+) A-I      intronic
chr16:15498422(+) A-I      intronic
chr16:15498558(+) A-I      intronic
chr16:15497297(+) A-I      intronic
chr16:15499524(+) A-I      intronic
chr16:15492082(+) A-I      intronic
chr16:15497132(+) A-I      intronic
chr16:15501439(+) A-I      intronic
chr16:15496958(+) A-I      intronic
chr16:15495615(+) A-I      intronic
chr16:15502837(+) A-I      3'UTR
chr16:15503119(+) A-I      3'UTR
chr16:15502823(+) A-I      3'UTR
chr16:15502589(+) A-I      3'UTR
chr16:15503139(+) A-I      3'UTR
chr16:15502621(+) A-I      3'UTR
chr16:15502800(+) A-I      3'UTR
chr16:15502693(+) A-I      3'UTR
chr16:15502900(+) A-I      3'UTR
chr16:15502831(+) A-I      3'UTR
chr16:15502849(+) A-I      3'UTR
chr16:15503068(+) A-I      3'UTR
chr16:15497473(+) A-I      intronic
chr16:15497079(+) A-I      intronic
chr16:15495423(+) A-I      intronic
chr16:15501520(+) A-I      intronic
chr16:15493723(+) A-I      intronic
chr16:15497146(+) A-I      intronic
chr16:15495557(+) A-I      intronic
chr16:15493890(+) A-I      intronic
chr16:15497416(+) A-I      intronic
chr16:15495422(+) A-I      intronic
chr16:15499926(+) A-I      intronic
chr16:15492162(+) A-I      intronic
chr16:15497394(+) A-I      intronic
chr16:15496721(+) A-I      intronic
chr16:15499484(+) A-I      intronic
chr16:15497098(+) A-I      intronic
chr16:15499471(+) A-I      intronic
chr16:15496601(+) A-I      intronic
chr16:15497105(+) A-I      intronic
chr16:15497147(+) A-I      intronic
chr16:15496609(+) A-I      intronic
chr16:15497449(+) A-I      intronic
chr16:15499525(+) A-I      intronic
chr16:15497171(+) A-I      intronic
chr16:15496578(+) A-I      intronic
chr16:15500758(+) A-I      intronic
chr16:15497384(+) A-I      intronic
chr16:15500708(+) A-I      intronic
chr16:15496799(+) A-I      intronic
chr16:15497010(+) A-I      intronic
chr16:15497176(+) A-I      intronic
chr16:15495583(+) A-I      intronic
chr16:15497313(+) A-I      intronic
chr16:15499870(+) A-I      intronic
chr16:15495566(+) A-I      intronic
chr16:15498516(+) A-I      intronic
chr16:15500711(+) A-I      intronic
chr16:15498591(+) A-I      intronic
chr16:15498423(+) A-I      intronic
chr16:15498502(+) A-I      intronic
chr16:15498559(+) A-I      intronic
chr16:15500732(+) A-I      intronic
chr16:15497039(+) A-I      intronic
chr16:15497401(+) A-I      intronic
chr16:15493725(+) A-I      intronic
chr16:15497047(+) A-I      intronic
chr16:15493940(+) A-I      intronic
chr16:15501328(+) A-I      intronic
chr16:15492027(+) A-I      intronic
chr16:15492040(+) A-I      intronic
chr16:15497906(+) A-I      intronic
chr16:15502978(+) A-I      3'UTR
chr16:15503084(+) A-I      3'UTR
chr16:15502564(+) A-I      3'UTR
chr16:15503040(+) A-I      3'UTR
chr16:15502599(+) A-I      3'UTR
chr16:15502665(+) A-I      3'UTR
chr16:15502869(+) A-I      3'UTR
chr16:15502877(+) A-I      3'UTR
chr16:15502667(+) A-I      3'UTR
chr16:15502899(+) A-I      3'UTR
chr16:15502563(+) A-I      3'UTR
chr16:15502586(+) A-I      3'UTR
chr16:15502756(+) A-I      3'UTR
chr16:15503122(+) A-I      3'UTR
chr16:15502539(+) A-I      3'UTR
chr16:15502804(+) A-I      3'UTR
chr16:15503013(+) A-I      3'UTR
chr16:15503018(+) A-I      3'UTR
chr16:15502778(+) A-I      3'UTR
chr16:15502784(+) A-I      3'UTR
chr16:15503048(+) A-I      3'UTR
chr16:15502722(+) A-I      3'UTR
chr16:15502560(+) A-I      3'UTR
chr16:15502559(+) A-I      3'UTR
chr16:15502962(+) A-I      3'UTR
chr16:15502764(+) A-I      3'UTR
chr16:15503091(+) A-I      3'UTR
chr16:15502716(+) A-I      3'UTR
chr16:15503039(+) A-I      3'UTR
chr16:15502820(+) A-I      3'UTR
chr16:15503126(+) A-I      3'UTR
chr16:15502912(+) A-I      3'UTR
chr16:15503078(+) A-I      3'UTR
chr16:15502577(+) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED MPV17L
chr16:15502962(+) A-I intron -    21960545
chr16:15503078(+) A-I intron -    21960545

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MPV17L
chr16:15489693-15489694(+) m6A 5'UTR       24981863
chr16:15489752-15489753(+) m6A 5'UTR       24981863
chr16:15501936-15501937(+) m6A 3'UTR//CDS       24981863
chr16:15501979-15501980(+) m6A 3'UTR       24981863
chr16:15501993-15501994(+) m6A 3'UTR       24981863
chr16:15502032-15502033(+) m6A 3'UTR       24981863
chr16:15503411-15503412(+) m6A 3'UTR       24981863
chr16:15503423-15503424(+) m6A 3'UTR       24981863
chr16:15503443-15503444(+) m6A 3'UTR       24981863
chr16:15503453-15503454(+) m6A 3'UTR       24981863
chr16:15503494-15503495(+) m6A 3'UTR       24981863
chr16:15503524-15503525(+) m6A 3'UTR       24981863
chr16:15503572-15503573(+) m6A 3'UTR       24981863
chr16:15503581-15503582(+) m6A 3'UTR       24981863
chr16:15505009-15505010(+) m6A 3'UTR       24981863
chr16:15505091-15505092(+) m6A 3'UTR       24981863
chr16:15505099-15505100(+) m6A 3'UTR       24981863
chr16:15505110-15505111(+) m6A 3'UTR       24981863
chr16:15505400-15505401(+) m6A 3'UTR       24981863
chr16:15505611-15505612(+) m6A 3'UTR       24981863
chr16:15505634-15505635(+) m6A 3'UTR       24981863
chr16:15505668-15505669(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
MPV17L
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: MPV17L

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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