Detail Information

Basic Information:


  VIRBase ID:  

HHID00098616

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 NAPEPLD
miRBase
Accession/Entrez ID		 hsa_circ_0002248 222236
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - C7orf18//FMP30//NAPE-PLD

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR NAPEPLD
chr7:102782887(-) A-I      intronic
chr7:102782890(-) A-I      intronic
chr7:102782953(-) A-I      intronic
chr7:102783009(-) A-I      intronic
chr7:102780873(-) A-I      intronic
chr7:102769530(-) A-I      intronic
chr7:102771118(-) A-I      intronic
chr7:102756633(-) A-I      intronic
chr7:102767182(-) A-I      intronic
chr7:102756624(-) A-I      intronic
chr7:102776947(-) A-I      intronic
chr7:102767225(-) A-I      intronic
chr7:102746223(-) A-I      intronic
chr7:102746214(-) A-I      intronic
chr7:102767228(-) A-I      intronic
chr7:102778953(-) A-I      intronic
chr7:102777408(-) A-I      intronic
chr7:102776951(-) A-I      intronic
chr7:102777525(-) A-I      intronic
chr7:102780869(-) A-I      intronic
chr7:102758512(-) A-I      intronic
chr7:102776613(-) A-I      intronic
chr7:102771289(-) A-I      intronic
chr7:102764904(-) A-I      intronic
chr7:102776700(-) A-I      intronic
chr7:102778141(-) A-I      intronic
chr7:102764649(-) A-I      intronic
chr7:102756729(-) A-I      intronic
chr7:102767108(-) A-I      intronic
chr7:102746208(-) A-I      intronic
chr7:102776760(-) A-I      intronic
chr7:102778177(-) A-I      intronic
chr7:102778181(-) A-I      intronic
chr7:102756637(-) A-I      intronic
chr7:102743338(-) A-I      3'UTR
chr7:102740605(-) A-I      3'UTR
chr7:102743349(-) A-I      3'UTR
chr7:102743354(-) A-I      3'UTR
chr7:102743359(-) A-I      3'UTR
chr7:102743362(-) A-I      3'UTR
chr7:102743373(-) A-I      3'UTR
chr7:102743377(-) A-I      3'UTR
chr7:102743335(-) A-I      3'UTR
chr7:102743324(-) A-I      3'UTR
chr7:102743320(-) A-I      3'UTR
chr7:102743315(-) A-I      3'UTR
chr7:102740582(-) A-I      3'UTR
chr7:102740581(-) A-I      3'UTR
chr7:102740576(-) A-I      3'UTR
chr7:102740560(-) A-I      3'UTR
chr7:102756704(-) A-I      intronic
chr7:102758514(-) A-I      intronic
chr7:102758572(-) A-I      intronic
chr7:102777589(-) A-I      intronic
chr7:102756713(-) A-I      intronic
chr7:102764531(-) A-I      intronic
chr7:102766251(-) A-I      intronic
chr7:102758621(-) A-I      intronic
chr7:102756692(-) A-I      intronic
chr7:102758553(-) A-I      intronic
chr7:102778563(-) A-I      intronic
chr7:102767192(-) A-I      intronic
chr7:102776602(-) A-I      intronic
chr7:102766569(-) A-I      intronic
chr7:102764823(-) A-I      intronic
chr7:102777651(-) A-I      intronic
chr7:102756689(-) A-I      intronic
chr7:102762657(-) A-I      intronic
chr7:102776476(-) A-I      intronic
chr7:102766168(-) A-I      intronic
chr7:102776774(-) A-I      intronic
chr7:102742868(-) A-I      3'UTR
chr7:102758379(-) A-I      intronic
chr7:102766551(-) A-I      intronic
chr7:102756649(-) A-I      intronic
chr7:102764783(-) A-I      intronic
chr7:102779189(-) A-I      intronic
chr7:102776912(-) A-I      intronic
chr7:102777524(-) A-I      intronic
chr7:102764532(-) A-I      intronic
chr7:102777590(-) A-I      intronic
chr7:102764905(-) A-I      intronic
chr7:102756623(-) A-I      intronic
chr7:102784389(-) A-I      intronic
chr7:102778562(-) A-I      intronic
chr7:102779044(-) A-I      intronic
chr7:102772032(-) A-I      intronic
chr7:102766528(-) A-I      intronic
chr7:102778463(-) A-I      intronic
chr7:102766151(-) A-I      intronic
chr7:102758447(-) A-I      intronic
chr7:102767207(-) A-I      intronic
chr7:102767151(-) A-I      intronic
chr7:102764492(-) A-I      intronic
chr7:102772478(-) A-I      intronic
chr7:102764781(-) A-I      intronic
chr7:102772024(-) A-I      intronic
chr7:102767194(-) A-I      intronic
chr7:102764793(-) A-I      intronic
chr7:102767169(-) A-I      intronic
chr7:102764822(-) A-I      intronic
chr7:102778211(-) A-I      intronic
chr7:102764805(-) A-I      intronic
chr7:102786761(-) A-I      intronic
chr7:102776768(-) A-I      intronic
chr7:102771923(-) A-I      intronic
chr7:102778944(-) A-I      intronic
chr7:102766148(-) A-I      intronic
chr7:102766085(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED NAPEPLD
chr7:102756704(-) A-I intron -    15258596
chr7:102758464(-) A-I intron -    15258596
chr7:102758467(-) A-I intron -    15258596
chr7:102748690(-) T-C intron -    22484847
chr7:102764531(-) A-G intron -    22484847
chr7:102764546(-) A-G intron -    22484847
chr7:102764781(-) A-G intron -    22484847
chr7:102764783(-) A-G intron -    22484847
chr7:102764793(-) A-G intron -    22484847
chr7:102764822(-) A-G intron -    22484847
chr7:102764823(-) A-G intron -    22484847
chr7:102766251(-) A-G intron -    22484847
chr7:102766551(-) A-G intron -    22484847
chr7:102766569(-) A-G intron -    22484847
chr7:102767139(-) A-G intron -    22484847
chr7:102767192(-) A-G intron -    22484847
chr7:102767274(-) A-G intron -    22484847
chr7:102767361(-) A-G intron -    22484847
chr7:102777515(-) A-G intron -    22484847
chr7:102777589(-) A-G intron -    22484847
chr7:102777590(-) A-G intron -    22484847
chr7:102778562(-) A-G intron -    22484847
chr7:102778563(-) A-G intron -    22484847
chr7:102779040(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NAPEPLD
chr7:102743142-102743143(-) m6A 3'UTR//exon//intron       27773535
chr7:102743228-102743229(-) m6A 3'UTR//exon//intron       27773535
chr7:102743768-102743769(-) m6A 3'UTR//exon//intron       27773535
chr7:102743810-102743811(-) m6A 3'UTR//exon//intron       24981863//27773535
chr7:102743822-102743823(-) m6A 3'UTR//exon//intron       24981863//27773535
chr7:102743882-102743883(-) m6A CDS//exon       24981863//27773535//22608085
chr7:102743950-102743951(-) m6A CDS//exon       24981863//27773535//22608085
chr7:102755526-102755527(-) m6A CDS//exon       24981863//27773535//22608085
chr7:102755556-102755557(-) m6A CDS//exon       24981863//27773535//22608085
chr7:102755594-102755595(-) m6A CDS//exon       27773535
chr7:102755684-102755685(-) m6A exon//intron       27773535
chr7:102760067-102760068(-) m6A CDS       27773535
chr7:102760192-102760193(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr7:102760244-102760245(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr7:102760272-102760273(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr7:102760389-102760390(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr7:102760442-102760443(-) m6A CDS       24284625//24209618//24981863//22608085
chr7:102760571-102760572(-) m6A CDS       24981863//27773535//22608085
chr7:102760655-102760656(-) m6A CDS       24981863//22608085
chr7:102760662-102760663(-) m6A CDS       24981863//22608085
chr7:102760667-102760668(-) m6A CDS       24981863//22608085
chr7:102767290-102767291(-) m6A exon//intron       22608085
chr7:102769002-102769003(-) m6A CDS//exon       24981863//27773535//22608085
chr7:102769076-102769077(-) m6A CDS//exon       24981863//27773535//22608085
chr7:102769088-102769089(-) m6A CDS//exon       24981863//27773535//22608085
chr7:102781827-102781828(-) m6A intron       24981863
chr7:102781890-102781891(-) m6A intron       24981863
chr7:102781943-102781944(-) m6A intron       24981863
chr7:102781966-102781967(-) m6A intron       24981863
chr7:102789630-102789631(-) m6A 5'UTR//intron       25456834
chr7:102789763-102789764(-) m6A 5'UTR       27773536
chr7:102789786-102789787(-) m6A 5'UTR       27773536
chr7:102789842-102789843(-) m6A 5'UTR       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
NAPEPLD
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: NAPEPLD

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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