Detail Information

Basic Information:


  VIRBase ID:  

HHID00098604

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 ATP6V0E2
miRBase
Accession/Entrez ID		 hsa_circ_0002248 155066
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - ATP6V0E2L//C7orf32

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ATP6V0E2
chr7:149573279(+) A-I      intronic
chr7:149573371(+) A-I      intronic
chr7:149573386(+) A-I      intronic
chr7:149574444(+) A-I      intronic
chr7:149574539(+) A-I      intronic
chr7:149573415(+) A-I      intronic
chr7:149573447(+) A-I      intronic
chr7:149574413(+) A-I      intronic
chr7:149574460(+) A-I      intronic
chr7:149574365(+) A-I      intronic
chr7:149574518(+) A-I      intronic
chr7:149574471(+) A-I      intronic
chr7:149574455(+) A-I      intronic
chr7:149574348(+) A-I      intronic
chr7:149574535(+) A-I      intronic
chr7:149573283(+) A-I      intronic
chr7:149574411(+) A-I      intronic
chr7:149574545(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ATP6V0E2
chr7:149575569(+) A-I intron -    15342557   //15258596
chr7:149575575(+) A-I intron -    15342557   //15258596
chr7:149575590(+) A-I intron -    15342557   //15258596
chr7:149575594(+) A-I intron -    15342557   //15258596
chr7:149575650(+) A-I intron -    15342557   //15258596
chr7:149575652(+) A-I intron -    15342557   //15258596
chr7:149575654(+) A-I intron -    15342557   //15258596
chr7:149575688(+) A-I intron -    15258596

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ATP6V0E2
chr7:149570602-149570603(+) m6A 5'UTR       24981863//27371828//27773536//22608085
chr7:149570616-149570617(+) m6A 5'UTR       24981863//27371828//27773536//22608085
chr7:149570625-149570626(+) m6A 5'UTR       27773536//22608085
chr7:149570779-149570780(+) m6A 5'UTR       25456834//27773536
chr7:149570793-149570794(+) m6A 5'UTR       25456834//27773536
chr7:149570867-149570868(+) m6A 5'UTR       25456834
chr7:149570888-149570889(+) m6A 5'UTR       -
chr7:149571090-149571091(+) m6A 5'UTR//CDS       24981863
chr7:149575795-149575796(+) m6A 3'UTR//CDS//exon//intron       -
chr7:149575827-149575828(+) m6A 3'UTR//CDS//exon//intron       24284625
chr7:149575921-149575922(+) m6A 3'UTR//intron       24284625
chr7:149576273-149576274(+) m6A 3'UTR//intron       -
chr7:149576480-149576481(+) m6A 3'UTR//CDS//exon       -
chr7:149576750-149576751(+) m6A 3'UTR//CDS       25456834//24981863//26404942
chr7:149576771-149576772(+) m6A 3'UTR       25456834//24981863//26404942
chr7:149576855-149576856(+) m6A 3'UTR       25456834//24981863
chr7:149577392-149577393(+) m6A 3'UTR       24284625//24209618
chr7:149577532-149577533(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085
chr7:149577746-149577747(+) m6A 3'UTR       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
ATP6V0E2
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: ATP6V0E2

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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