Detail Information

Basic Information:


  VIRBase ID:  

HHID00098599

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 CCDC24
miRBase
Accession/Entrez ID		 hsa_circ_0002248 149473
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - -

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CCDC24
chr1:44460007(+) A-I      ncRNA
chr1:44459968(+) A-I      ncRNA
chr1:44459862(+) A-I      ncRNA
chr1:44459970(+) A-I      ncRNA
chr1:44459908(+) A-I      ncRNA
chr1:44459863(+) A-I      ncRNA
chr1:44459974(+) A-I      ncRNA
chr1:44460360(+) A-I      ncRNA
chr1:44460049(+) A-I      ncRNA
chr1:44460373(+) A-I      ncRNA
chr1:44460000(+) A-I      ncRNA
chr1:44459919(+) A-I      ncRNA
chr1:44459992(+) A-I      ncRNA
chr1:44458857(+) A-I      intronic
chr1:44460230(+) A-I      ncRNA
chr1:44460256(+) A-I      ncRNA
chr1:44459956(+) A-I      ncRNA
chr1:44459912(+) A-I      ncRNA
chr1:44459922(+) A-I      ncRNA
chr1:44459939(+) A-I      ncRNA
chr1:44460053(+) A-I      ncRNA
chr1:44460365(+) A-I      ncRNA
chr1:44459932(+) A-I      ncRNA
chr1:44460252(+) A-I      ncRNA
chr1:44460242(+) A-I      ncRNA
chr1:44459965(+) A-I      ncRNA
chr1:44459931(+) A-I      ncRNA
chr1:44460187(+) A-I      ncRNA
chr1:44459967(+) A-I      ncRNA
chr1:44460028(+) A-I      ncRNA
chr1:44460324(+) A-I      ncRNA
chr1:44460389(+) A-I      ncRNA
chr1:44460249(+) A-I      ncRNA
chr1:44459860(+) A-I      ncRNA
chr1:44460254(+) A-I      ncRNA
chr1:44460295(+) A-I      ncRNA
chr1:44459918(+) A-I      ncRNA
chr1:44460387(+) A-I      ncRNA
chr1:44460320(+) A-I      ncRNA
chr1:44460087(+) A-I      ncRNA
chr1:44460059(+) A-I      ncRNA
chr1:44459940(+) A-I      ncRNA
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CCDC24
chr1:44459860(+) A-I intron -    15342557   //22327324
chr1:44459918(+) A-I intron -    15342557
chr1:44459931(+) A-I intron -    15342557
chr1:44459932(+) A-I intron -    15342557
chr1:44459940(+) A-I intron -    15342557
chr1:44459967(+) A-I intron -    15342557
chr1:44460028(+) A-I intron -    15342557
chr1:44460053(+) A-I intron -    15342557
chr1:44460059(+) A-I intron -    15342557
chr1:44460087(+) A-I intron -    15342557
chr1:44460187(+) A-I intron -    15342557   //15258596
chr1:44460242(+) A-I intron -    15342557   //15258596
chr1:44460249(+) A-I intron -    15342557
chr1:44460252(+) A-I intron -    15342557
chr1:44460254(+) A-I intron -    15342557
chr1:44460295(+) A-I intron -    15342557
chr1:44460320(+) A-I intron -    15342557   //15258596
chr1:44460324(+) A-I intron -    15342557   //15258596
chr1:44460365(+) A-I intron -    15342557   //15258596
chr1:44460387(+) A-I intron -    15342557   //15258596
chr1:44460389(+) A-I intron -    15342557   //15258596

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CCDC24
chr1:44457363-44457364(+) m6A 5'UTR//exon//intron       25456834
chr1:44457400-44457401(+) m6A 5'UTR//exon//intron       25456834
chr1:44457650-44457651(+) m6A CDS//exon       24284625
chr1:44461466-44461467(+) m1A 3'UTR//CDS//exon       26863410
chr1:44462090-44462091(+) m6A 3'UTR//exon       24981863
chr1:44462130-44462131(+) m6A 3'UTR//exon       24981863
chr1:44462136-44462137(+) m6A 3'UTR//exon       24981863
chr1:44462160-44462161(+) m6A 3'UTR//exon       24981863
chr1:44462191-44462192(+) m6A 3'UTR//exon       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
CCDC24
Chromatin K562 cells     -
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: CCDC24

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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