Detail Information

Basic Information:


  VIRBase ID:  

HHID00098565

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 MYADM
miRBase
Accession/Entrez ID		 hsa_circ_0002248 91663
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - SB135

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MYADM
chr19:54379054(+) A-I      3'UTR
chr19:54378889(+) A-I      3'UTR
chr19:54378893(+) A-I      3'UTR
chr19:54378901(+) A-I      3'UTR
chr19:54378902(+) A-I      3'UTR
chr19:54378938(+) A-I      3'UTR
chr19:54379013(+) A-I      3'UTR
chr19:54379061(+) A-I      3'UTR
chr19:54378943(+) A-I      3'UTR
chr19:54378950(+) A-I      3'UTR
chr19:54378953(+) A-I      3'UTR
chr19:54379016(+) A-I      3'UTR
chr19:54379024(+) A-I      3'UTR
chr19:54379025(+) A-I      3'UTR
chr19:54379038(+) A-I      3'UTR
chr19:54379045(+) A-I      3'UTR
chr19:54379048(+) A-I      3'UTR
chr19:54379049(+) A-I      3'UTR
chr19:54379053(+) A-I      3'UTR
chr19:54374378(+) A-I      intronic
chr19:54374442(+) A-I      intronic
chr19:54375697(+) A-I      intronic
chr19:54375726(+) A-I      intronic
chr19:54375854(+) A-I      intronic
chr19:54375900(+) A-I      intronic
chr19:54376578(+) A-I      intronic
chr19:54374251(+) A-I      intronic
chr19:54374265(+) A-I      intronic
chr19:54374275(+) A-I      intronic
chr19:54374343(+) A-I      intronic
chr19:54374374(+) A-I      intronic
chr19:54375295(+) A-I      intronic
chr19:54376002(+) A-I      intronic
chr19:54375873(+) A-I      intronic
chr19:54375793(+) A-I      intronic
chr19:54375878(+) A-I      intronic
chr19:54375292(+) A-I      intronic
chr19:54376576(+) A-I      intronic
chr19:54376587(+) A-I      intronic
chr19:54376546(+) A-I      intronic
chr19:54375500(+) A-I      intronic
chr19:54375579(+) A-I      intronic
chr19:54376447(+) A-I      intronic
chr19:54375964(+) A-I      intronic
chr19:54374437(+) A-I      intronic
chr19:54376547(+) A-I      intronic
chr19:54376016(+) A-I      intronic
chr19:54374391(+) A-I      intronic
chr19:54376368(+) A-I      intronic
chr19:54374207(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MYADM
chr19:54371138-54371139(+) m6A 5'UTR//intron       24284625//24209618//24981863
chr19:54372689-54372690(+) m6A 5'UTR//intron       24284625//24209618//24981863
chr19:54373085-54373086(+) m6A 5'UTR//intron       24284625//24981863
chr19:54377186-54377187(+) m6A CDS       24284625//24981863
chr19:54377254-54377255(+) m6A CDS       24284625//24981863
chr19:54377323-54377324(+) m6A CDS       24284625//24981863//22575960
chr19:54377453-54377454(+) m6A CDS       24284625//24209618//24981863//26404942//22575960
chr19:54377654-54377655(+) m6A CDS       24284625//24209618//24981863
chr19:54377753-54377754(+) m6A 3'UTR       24284625//24209618//24981863
chr19:54378168-54378169(+) m6A 3'UTR       24284625//24209618//25456834//24981863
chr19:54378306-54378307(+) m6A 3'UTR       24209618
chr19:54378866-54378867(+) m6A 3'UTR       24284625//24209618//25456834//24981863
chr19:54378903-54378904(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr19:54379001-54379002(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr19:54379007-54379008(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr19:54379083-54379084(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:54379093-54379094(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:54379129-54379130(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:54379146-54379147(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:54379172-54379173(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:54379310-54379311(+) m6A 3'UTR       24284625//26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
MYADM
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: MYADM

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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