Detail Information

Basic Information:


  VIRBase ID:  

HHID00098299

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0002248 hsa-miR-619-5p
miRBase
Accession/Entrez ID		 hsa_circ_0002248 MIMAT0026622
Organism Homo sapiens Homo sapiens
Category circRNA miRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-619-5p
rs1173633685 chr12:108836970    C/A
rs1360600602 chr12:108836973    G/A
rs368283564 chr12:108836983    C/A
rs747519669 chr12:108836968    T/A
rs747519669 chr12:108836968    T/G
rs1395416108 chr12:108836979    C/G
rs1466244611 chr12:108836977    T/C

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0002248
Exosome Blood     -
hsa-miR-619-5p
Exosome Pooled sera     27278097
Exosome Serum     24683445
Exosome Kidney tissue     -
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0002248
Interactor2: hsa-miR-619-5p

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression Downregulation
Tissue or cell line Calu-3 cells Interactor2 expression Upregulation
Description The circRNA-miRNA pairs with strong negative correlations were selected for circRNA-miRNA binding site prediction using miRanda (http://www.microrna.org/) v3.3a.

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