Detail Information

Basic Information:


  VIRBase ID:  

HHID00098290

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa_circ_0001680 APLF
miRBase
Accession/Entrez ID		 hsa_circ_0001680 200558
Organism Homo sapiens Homo sapiens
Category circRNA mRNA
Alias - APFL//C2orf13//PALF//Xip1//ZCCHH1

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR APLF
chr2:68701901(+) A-I      intronic
chr2:68726794(+) A-I      intronic
chr2:68752968(+) A-I      intronic
chr2:68726949(+) A-I      intronic
chr2:68752348(+) A-I      intronic
chr2:68702009(+) A-I      intronic
chr2:68707633(+) A-I      intronic
chr2:68701959(+) A-I      intronic
chr2:68711667(+) A-I      intronic
chr2:68752349(+) A-I      intronic
chr2:68711774(+) A-I      intronic
chr2:68704559(+) A-I      intronic
chr2:68704563(+) A-I      intronic
chr2:68703495(+) A-I      intronic
chr2:68701930(+) A-I      intronic
chr2:68752956(+) A-I      intronic
chr2:68703408(+) A-I      intronic
chr2:68703362(+) A-I      intronic
chr2:68703462(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED APLF
chr2:68724865(+) A-G intron -    22484847
chr2:68724913(+) A-G intron -    22484847
chr2:68703362(+) A-G intron -    22484847
chr2:68703408(+) A-G intron -    22484847
chr2:68703488(+) A-G intron -    22484847
chr2:68703495(+) A-G intron -    22484847
chr2:68704559(+) A-G intron -    22484847
chr2:68704563(+) A-G intron -    22484847
chr2:68707633(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase APLF
chr2:68765063-68765064(+) m6A 3'UTR//CDS//exon       22608085
chr2:68765079-68765080(+) m6A 3'UTR//CDS//exon       24981863//22608085
chr2:68765098-68765099(+) m6A 3'UTR//CDS//exon       24981863//22608085
chr2:68765116-68765117(+) m6A 3'UTR//CDS//exon       24981863//22608085
chr2:68765138-68765139(+) m6A 3'UTR//CDS//exon       24981863//22608085
chr2:68805041-68805042(+) m6A 3'UTR//CDS//exon       27773535
chr2:68805075-68805076(+) m6A 3'UTR//CDS//exon       27773535
chr2:68870881-68870882(+) m6A intron       25456834
chr2:68870943-68870944(+) m6A intron       25456834
chr2:68870949-68870950(+) m6A intron       25456834
chr2:68872839-68872840(+) m6A exon       25456834//24981863
chr2:68872901-68872902(+) m6A exon       25456834//24981863
chr2:68872959-68872960(+) m6A CDS//exon       25456834
chr2:68873191-68873192(+) m6A CDS//exon       25456834//24981863
chr2:68873228-68873229(+) m6A CDS//exon       25456834//24981863
chr2:68873314-68873315(+) m6A CDS//exon       25456834//24981863
chr2:68882643-68882644(+) m6A CDS//exon       25456834//24981863
chr2:68882649-68882650(+) m6A CDS//exon       25456834//24981863
chr2:68882657-68882658(+) m6A CDS//exon       25456834//24981863
chr2:68882688-68882689(+) m6A CDS//exon       25456834//24981863
chr2:68882698-68882699(+) m6A CDS//exon       25456834//24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa_circ_0001680
Exosome Blood     -
APLF
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa_circ_0001680
Interactor2: APLF

Evidence Support:


Weak-Evidence Illumina sequencing
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression None
Description The mRNA-circRNA pairs with strong positive correlations were defined as those having r >0.7 and cP <0.05.

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