Detail Information

Basic Information:


  VIRBase ID:  

HHID00096593

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-150-5p:           TLR3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-150-5p TLR3
miRBase
Accession/Entrez ID
MIMAT0000451 7098
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CD283//IIAE2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-150-5p
rs1303487637 chr19:49500840    C/A
rs1339016814 chr19:49500833    A/AGGCC
rs1368638183 chr19:49500833    A/C
rs1405626581 chr19:49500837    G/A
rs1407035158 chr19:49500839    A/G
rs955899705 chr19:49500843    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TLR3
chr4:187001863(+) A-I      intronic
chr4:187003336(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TLR3
chr4:186990367-186990368(+) m6A 5'UTR       24981863
chr4:186997778-186997779(+) m6A CDS       24981863
chr4:187003525-187003526(+) m6A 5'UTR//CDS//exon       24981863
chr4:187003579-187003580(+) m6A 5'UTR//CDS//exon       24981863
chr4:187003649-187003650(+) m6A 5'UTR//CDS//exon       24981863
chr4:187003659-187003660(+) m6A 5'UTR//CDS//exon       24981863
chr4:187003978-187003979(+) m6A CDS//exon       24981863
chr4:187004022-187004023(+) m6A CDS//exon       24284625//24981863
chr4:187004037-187004038(+) m6A CDS//exon       24284625//24981863
chr4:187004177-187004178(+) m6A CDS//exon       24209618//24981863
chr4:187004260-187004261(+) m6A CDS//exon       24284625//24209618//24981863
chr4:187004635-187004636(+) m6A CDS//exon       24981863
chr4:187004686-187004687(+) m6A CDS//exon       24981863
chr4:187004746-187004747(+) m6A CDS//exon       24981863
chr4:187004829-187004830(+) m6A CDS//exon       24284625//24209618//24981863
chr4:187004906-187004907(+) m6A CDS//exon       24284625//24209618//24981863
chr4:187004932-187004933(+) m6A CDS//exon       24284625//24209618//24981863
chr4:187004948-187004949(+) m6A CDS//exon       24284625//24209618//24981863
chr4:187005082-187005083(+) m6A CDS//exon       24284625//24981863
chr4:187005090-187005091(+) m6A CDS//exon       24284625//24981863
chr4:187005095-187005096(+) m6A CDS//exon       24284625//24981863
chr4:187005155-187005156(+) m6A CDS//exon       24284625//24981863
chr4:187005181-187005182(+) m6A CDS//exon       24284625//25456834//24981863
chr4:187005214-187005215(+) m6A CDS//exon       25456834//24981863
chr4:187005236-187005237(+) m6A CDS//exon       25456834//24981863
chr4:187005310-187005311(+) m6A CDS//exon       24981863
chr4:187005888-187005889(+) m6A CDS//exon       24981863
chr4:187005893-187005894(+) m6A CDS//exon       24981863
chr4:187005944-187005945(+) m6A CDS//exon       24981863
chr4:187006013-187006014(+) m6A CDS//exon       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-150-5p
Exosome Peripheral blood     31746410
Exosome Primary ovarian tumor cells|Serum     18589210
Exosome Saliva     19627513
Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk     22211110
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Serum     25135963
Exosome Blood|B lymphoblastoid cells|Colon tissue|Endothelial cells|Lymphoma tissue|Mast cells     -
Extracellular Vesicle Plasma     28588009
Extracellular vesicle HEK-293T cells     22849433
Lysosome HeLa cells|MCF-7 cells     29784380
Microvesicle Follicular fluid     23666971
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Human cervical cancer cell line (HeLa)|Breast cancer cell line (MCF-7)     29784380
TLR3
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID
Function
ncDR hsa-miR-150-5p
Iodine Green 9956454 Drug sensitive
Piperidine, 2-methyl-6-undecyl- 99090 Drug sensitive
2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug sensitive
5-Iodo-8-quinolinol 96111 Drug sensitive
Actinomycin X4357G methoxime 9573583 Drug sensitive
[[4-(3-Aminophenyl)-2-pyridyl]methyleneamino]thiourea 9556427 Drug sensitive
5-Fluorouridine 9427 Drug sensitive
Dichlorodipropylstannane 93562 Drug sensitive
Cyclo[N-methyl-L-alanyl-beta-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl] 91746256 Drug sensitive
Ethyl phenylpropiolate 91516 Drug sensitive
[(1R,2Z,4R,8R,9R,11R,12S)-1,12-Dihydroxy-2-(hydroxymethyl)-11-methyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] (Z)-2-methylbut-2-enoate 90475906 Drug sensitive
[(1R,2S,6R,7R,9S,12S,13S)-13-(Acetyloxymethyl)-12-hydroxy-9-methyl-5-methylidene-4-oxo-3,14-dioxatricyclo[7.4.1.02,6]tetradecan-7-yl] (Z)-2-(acetyloxymethyl)but-2-enoate 90473692 Drug sensitive
(3R,10S,13S,16S,19R)-16-[(2S)-Butan-2-yl]-10,11,14-trimethyl-3-(2-methylpropyl)-13-propan-2-yl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone 90471303 Drug sensitive
2,5-Dimethyl-1,4-benzoquinone 8718 Drug sensitive
Acid Green 27 80837 Drug sensitive
Secalonic acid D 73431 Drug sensitive
Jacaranone 73307 Drug sensitive
Redoxal 72571 Drug sensitive
4-(2-Naphthylamino)phenol 7141 Drug sensitive
NO Data IN this field 6711510 Drug sensitive
Antineoplastic-301477 6711219 Drug sensitive
Verrucarin A 6326658 Drug sensitive
Chalcone analog 6296717 Drug sensitive
Primaquine phosphate 6135 Drug sensitive
Piriqualone 6015423 Drug sensitive
Verrucarin A, 3'-(acetyloxy)-7'-deoxo-2'-deoxy-4'-hydroxy-7'-(1-hydroxyethyl)- 5933240 Drug sensitive
Triethylenemelamine 5799 Drug sensitive
Liatris laevigata lactone #2 5477810 Drug sensitive
Caracemide 54747 Drug sensitive
7Z-Plakortide H 5472712 Drug sensitive
Tetrocarcin A, sodium salt 54724658 Drug sensitive
Artelasticin 5471311 Drug sensitive
Kijanimicin sodium salt 54707591 Drug sensitive
3-Deazauridine 54684286 Drug sensitive
(8R,9S,13S,14S,17S)-13-Methyl-2-[(E)-prop-1-enyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 5468270 Drug sensitive
(Z)-4-Bromo-4-iodo-3-phenylbut-3-en-2-one 5467656 Drug sensitive
[3-Keto-Bmt(sup 1)]-[Val(sup 2)]-Cyclosporin 5467197 Drug sensitive
3,19-(4-Acetamido)benzylidineandrographolide 54612901 Drug sensitive
9-alpha-Acetoxyparthenolide 54611286 Drug sensitive
p-Chloranilinum[bis(p-chloraniline)dioxalatoruthenate(III)] 54608061 Drug sensitive
Selendale 54601159 Drug resistant
Stereoisomer of 672120 (MW=262) 5459262 Drug sensitive
Betuletol 5459196 Drug sensitive
Cuspidatin C 5459164 Drug sensitive
Trunculin A 5459125 Drug sensitive
Thiram 5455 Drug sensitive
(E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive
Heliangolide 5384466 Drug sensitive
(1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive
Crassin, acetate 5355441 Drug sensitive
Hemiasterlin 5352092 Drug sensitive
Dihydro-5-azacytidine 5351280 Drug sensitive
4-(N-(4-Cyclohexylbenzyl)-2-(2,3,4,5,6-pentafluoro-N-methylphenylsulfonamido)acetamido)-2-hydroxybenzoic acid 53388144 Drug sensitive
Improsulfan hydrochloride 5284401 Drug sensitive
Erioflorin acetate 5281443 Drug sensitive
8-Hydroxymanzamine A 5270765 Drug sensitive
Pyrimethamine 4993 Drug sensitive
Ammonia; dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498559 Drug sensitive
Lychnopholide 49767028 Drug sensitive
Elsinochrome C 495866 Drug sensitive
1,4-Benzoquinone 4650 Drug sensitive
SMA-838 (HCl salt of NSC 188491) 45028430 Drug sensitive
Mycophenolic acid 446541 Drug sensitive
Isopinnatal 44558939 Drug sensitive
Oxyacanthine 442333 Drug sensitive
Isobrucein A 441802 Drug sensitive
Physalolactone 433866 Drug sensitive
Oridonin (thiol adduct OF) 432952 Drug sensitive
S-(Diisopropylarsino)-3-mercapto-1,2-propanediol 406478 Drug sensitive
11-Hydroxyusambarine Chlorhydrate 401426 Drug sensitive
Triacetyl crambescidin 800 hydrochloride 400721 Drug sensitive
Artelastin 399488 Drug sensitive
1H-Indole, 5-bromo-3-[2-(2-pyridinyl)-4-thiazolyl]- 397551 Drug sensitive
7-Epi-3,4-bis-nor-dolastatin 11 396354 Drug sensitive
Loratadine 3957 Drug sensitive
Lomustine 3950 Drug sensitive
2,5-Bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione 394347 Drug sensitive
Sjg-136 393111 Drug sensitive
2-Amino-4-(2-hydroxy-4-methylphenyl)-5-phenylpyrimidine 392744 Drug sensitive
1-(4'-Phthalimidopropyl-carbonyl)-5-fluorouracil 388985 Drug sensitive
beta-Lapachone 3885 Drug sensitive
3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant
N-(2-Bromo-5-methoxybenzylidene)-6,7-dimethoxy-1-naphthalenamine 387181 Drug sensitive
ARQ monoacetate 385441 Drug sensitive
Stereoisomer of NSC 674066-O 384359 Drug sensitive
1-Azido-2-phenyl-3-phenalenone 381891 Drug sensitive
2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant
Antineoplastic-656904 376224 Drug sensitive
Benzoxazole, 2-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]- 364608 Drug sensitive
4-(1-Benzofuran-2-yl)-7-methoxychromen-2-one 364364 Drug resistant
4-Nitro-6-(trifluoromethyl)-2,1,3-benzoselenadiazole 362897 Drug sensitive
Aplidazole C . TFA 362402 Drug sensitive
4-N,N-Bis-2'-cyanoethylaminobenzylidene-4-fluoro aniline 359414 Drug sensitive
Dolastatin 11 354399 Drug sensitive
Predorine 333830 Drug sensitive
4-Ethyl-6-methoxy-7-(oxiran-2-ylmethoxy)quinazoline 333565 Drug sensitive
Rocaglamide 331783 Drug sensitive
Helenin 327378 Drug sensitive
6-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)sulfanyl]-7H-purin-2-amine 3246652 Drug sensitive
Dmask 32465 Drug sensitive
2,2',3,3'-Tetrahydroxy-1,1'-binaphthyl 316673 Drug sensitive
2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive
1,4-Diaminoanthraquinone 31420 Drug sensitive
1,1-Dimethyl-5-(2-naphthalenyl)dithiobiuret 3004012 Drug sensitive
Carmofur 2577 Drug sensitive
2'-Deoxy-5-(trifluoromethyl)uridine 253083 Drug sensitive
9H-Purine, 6-(benzylthio)-9-(2-chloroethyl)- 246230 Drug sensitive
2[4'Aminobiphenyl]5,6dichlorobenzimidazole 24205088 Drug sensitive
Cinerubin A hcl 24196924 Drug sensitive
9H-Purin-2-amine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9-(2-methylpropyl)- 239491 Drug sensitive
9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive
7-Fluoro-2-benzoyl-3-trifluoromethylquioxaline 1,4-dioxide 23635154 Drug sensitive
[(1S,2Z,4R,8R,9R,11R,13S)-13-Acetyloxy-1-hydroxy-2,11-dimethyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] 2-methylpropanoate 23255746 Drug sensitive
Helenalin 23205 Drug sensitive
Drostanolone propionate 224004 Drug sensitive
Amsacrine 2179 Drug sensitive
(1S,3R,7Z,9R,12S,13R,15R)-13-Hydroxy-3,7,12-trimethyl-13-prop-1-en-2-yl-10,14,16-trioxatetracyclo[7.5.1.13,6.012,15]hexadeca-5,7-diene-4,11-dione 20835084 Drug sensitive
4-Chloro-5-(pyridin-2-ylthio)-3H-1,2-dithiole-3-thione 16766538 Drug sensitive
4-Chloro-5-phenoxy-3H-1,2-dithiole-3-thione 16766044 Drug sensitive
P-Dioxane,5-bis[(benzoyloxymercuri)methyl]- 16683647 Drug sensitive
1,2:5,6-Dianhydrogalactitol 15942827 Drug sensitive
2,6-Dibenzylidenecyclohexanone 1550330 Drug sensitive
8-Chloroadenosine 147569 Drug sensitive
Methyl (7E,9Z,11S,12R,13S,14R,15R,17R,18S,19S,20E)-2,16-diacetyloxy-11,12,14,18,19,31-hexahydroxy-3,7,11,13,17,19,21,27-octamethyl-6,28-dioxo-23,25-dioxa-5-azatetracyclo[20.7.1.14,29.026,30]hentriaconta-1,3,7,9,20,22(30),26,29(31)-octaene-15-carboxylate 138319233 Drug sensitive
Methyl (3'R)-3,4',9',10-tetrahydroxy-3'-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-7'-methoxy-5',8',9-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate 137326876 Drug sensitive
Astrazon Orange R 135747272 Drug sensitive
C8, Carbonyl prodigiosine 135540857 Drug sensitive
5-[(E)-[Amino(methyl)amino]azo]-1H-imidazole-4-carboxamide 135493930 Drug sensitive
Cysteine, S-[(4-aminocarbonyl-1H-imidazol-5-yl)azo]- 135493928 Drug sensitive
Mercury, (4-aminophenyl)(6-thioguanosinato-N7,S6)- 135403617 Drug sensitive
Inosine dialdehyde 135400916 Drug sensitive
DTIC-Dome 135398738 Drug sensitive
(1R,2S,5S,8S,9S,17R,18R,21S,24R,26S,27S)-14-Chloro-5,15-dihydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacos-11-ene-4,10,22,29-tetrone 134715214 Drug sensitive
2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-Deoxy-alpha-L-mannopyranosyl)-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-beta-D-glucopyranoside 132274946 Drug sensitive
Sendanin 12806435 Drug sensitive
Methotrexate 126941 Drug sensitive
15-Deacetylsergeolide 125729 Drug sensitive
(2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive
(1S,3R,7Z,9R,12S,13R,15S)-13-Butan-2-yl-13-hydroxy-3,7,12-trimethyl-10,14,16-trioxatetracyclo[7.5.1.13,6.012,15]hexadeca-5,7-diene-4,11-dione 11972510 Drug sensitive
Melampodinin 11953936 Drug sensitive
Unii-C616DV5Y11 117587576 Drug sensitive
p-Toluquinone 11122 Drug sensitive
Unii-9JU14BJ5QG 109374088 Drug sensitive
6-[4-(1-Cyclohexenyl)-1,3-butadiyn-1-yl]-2(2H)-pyranone 10263039 Drug sensitive
Fusariotoxin T-2 102515111 Drug sensitive
(7S,9S)-7-[[(3As,4S,7aS)-1-[[(3aS,4S,7aS)-4-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-1-yl]methyl]-4-methyl-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-6-yl]oxy]-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 101713728 Drug sensitive
Erigerol 101318126 Drug sensitive
[(1S,2S,4Z,8Z,12R,13S)-12-Hydroxy-4,8,12-trimethyl-16-methylidene-15-oxo-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] acetate 100921072 Drug sensitive
Cinnoline, 4-nitro-, 1-oxide 100397 Drug sensitive
1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1H-pyrazole - Drug resistant
1-naphthalenecarboxamide, n,n'-1,8-(octanediyl)bis- - Drug resistant
6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant
N3-[1-(3-phenoxybenzyl)-1H-1,2,3-triazol-4-yl]methyl-2-(4-fluoroanilino)nicotinamide - Drug resistant
(E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-5-(3-methyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole - Drug sensitive
1,1'-biphenyl, 4,4'bis(thiomethyl)- - Drug sensitive
1,3-isoquinolinedione, 4-[(3,4-dimethoxyphenyl)methylene]- - Drug sensitive
2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive
3,19-benzylidine-14-deoxy-11,12-didehydroandrographolide - Drug sensitive
4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug sensitive
4-[3-(3,4-dihydro-1H-isoquinolin-2-yl)prop-1-en-2-yl]-N-pyrazin-2-ylbenzamide - Drug sensitive
4'-deoxy-13',17-dinitro-3',4'-epoxy-vincaleukoblastine - Drug sensitive
4-morpholinecarbodithioic acid, antimony complex - Drug sensitive
4-piperidinone, 3,5-bis[(4-fluorophenyl)methylene]-, (e,e)- - Drug sensitive
5,6-dimethyl-9-oxo-9h-xanthene-4-acetic acid, sodium salt - Drug sensitive
7h-5,6-dithioleno[4,3-d]uracil - Drug sensitive
9h-purine, 2-amino-6-(2,4-dichlorobenzylthio)-9-isobutyl- - Drug sensitive
acetamide, n-(2-mercaptoethyl)-, benzoate (6ci, 7ci) - Drug sensitive
b676297k277 3',4'-deoxypsorospermin 3',4'-chlorohydrin - Drug sensitive
benzamide, 5-bromo-2-hydroxy-n-[3-(trifluoromethyl)phenyl]- - Drug sensitive
benzofurazan, 4-nitro-7-(2-pyridinylthio)-, n-oxide - Drug sensitive
ethyl-2,3-oxido-(5-bromo-2-methoxyphenyl)propionate - Drug sensitive
furan-2(3h)-one, 5-(4-methylphenyl)-3,3-diphenyl- - Drug sensitive
n,n'-bis(oxydiethylene)thiocarbamoylsulfenamide - Drug sensitive
Paracymene-ruthenium(II)-[N-(3-(1H-imidazol-1-yl)propyl)-4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8 tetrahydronaphthalen-2-yl)vinyl)benzamide] dichloride - Drug sensitive
phenol, 4,4'-(5,5'-biisoxazole-3,3'-diyl)bis- - Drug sensitive
propan-1-one, 2,3-dichloro-1,3-bis(4-methylphenyl)- - Drug sensitive
roridin a, 8-hydroxy-9b,10b-epoxy- - Drug sensitive
salicylaldehyde, 5-bromo- (8ci) - Drug sensitive
tris(1,3-diphenylpropane-1,3-dionata)gallium(iii) - Drug sensitive
(Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive
[bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug sensitive
10-hydroxy-scandine - Drug sensitive
4'-chloro-3-nitro-o-salicylotoluidide - Drug sensitive
5-methoxy camptothecin - Drug sensitive
7-propanoyltaxol - Drug sensitive
antineoplastic-d665837 - Drug sensitive
aromoline - Drug sensitive
arylmethylene-f - Drug sensitive
bisarylpurine - Drug sensitive
chlorobis(4-ethyltropolonato)bismuth(iii) - Drug sensitive
devadarool (erthoxydiol-x) - Drug sensitive
dicarboxylic acid derivative of sorangicin a - Drug sensitive
erytroxytriol-p - Drug sensitive
Indenoisoquinoline derivative - Drug sensitive
insulin-methotrexate conjugate - Drug sensitive
largomycin f-ii - Drug sensitive
Methotrexate Derivative - Drug sensitive
mitaplatin - Drug sensitive
organosulfur compound - Drug sensitive
pyrazoline derivative - Drug sensitive
secafascaplysin - Drug sensitive
Tetraplatin - Drug sensitive
Resource Symbol Drug Name PubChem
ID
Function Link  
RNAInter hsa-miR-150-5p
D-Glucose 5793 Drug interaction    RC00003180
Dexamethasone 5743 Drug interaction    RC00003179
Sunitinib 5329102 Drug interaction    RC00003189
Eloxatine 5310940 Drug interaction    RC00003188
Imatinib 5291 Drug interaction    RC00003178
Morphine 5288826 Drug interaction    RC00003187
Oxyphenbutazone 4641 Drug interaction    RC00003177
Etoposide 36462 Drug interaction    RC00003184
Doxorubicin 31703 Drug interaction    RC00003183
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00003176
Arsenic trioxide 14888 Drug interaction    RC00003182
Imatinib mesylate 123596 Drug interaction    RC00003186
Crizotinib 11626560 Drug interaction    RC00003190
Methamphetamine 10836 Drug interaction    RC00003181
Natalizumab - Drug interaction    RC00003191
Pertuzumab - Drug interaction    RC00003192
platinum-based doublet chemotherapy - Drug interaction    RC00003193
1,2,6-Tri-O-galloyl-beta-D-glucopyranose - Drug interaction    RC00003194
Glucocorticoid - Drug interaction    RC00003195
Marine fungal metabolite 1386A - Drug interaction    RC00003196

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-150-5p
Interactor2: TLR3

Evidence Support:


Strong-Evidence qRT-PCR
Support Database ViRBase

References:


PMID 20636339 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line CD4(+) T cells Interactor2 expression None
Description Further more, TLR-3 activation in macrophages induced the expression of cellular microRNAs(miRNA-28, -125b, -150, -223 and -382), the newly identified intracellular HIV restriction factors. TLR-3 activation inhibits HIV-1 infection of macrophages

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