Basic Information:

  VIRBase ID:  

HHID00096509

  Virus:  

Human immunodeficiency virus (HIV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-4677-3p:  MIMAT0019761          ATPSCKMT:  NR_047669     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-4677-3p	ATPSCKMT
miRBase Accession/Entrez ID	MIMAT0019761	134145
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	FAM173B//hFAM173B//JS-2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-4677-3p	rs1254655423 chr1:243346244    A/G rs1481229343 chr1:243346235    C/T rs771267188 chr1:243346242    C/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ATPSCKMT	chr5:10234393(-) A-I      intronic chr5:10246484(-) A-I      intronic chr5:10229009(-) A-I      intronic chr5:10247536(-) A-I      intronic chr5:10232246(-) A-I      intronic chr5:10234396(-) A-I      intronic chr5:10234357(-) A-I      intronic chr5:10228955(-) A-I      intronic chr5:10228884(-) A-I      intronic chr5:10228224(-) A-I      intronic chr5:10228859(-) A-I      intronic chr5:10232123(-) A-I      intronic chr5:10228961(-) A-I      intronic chr5:10244981(-) A-I      intronic chr5:10229037(-) A-I      intronic chr5:10234248(-) A-I      intronic chr5:10228864(-) A-I      intronic chr5:10228938(-) A-I      intronic chr5:10229000(-) A-I      intronic chr5:10228238(-) A-I      intronic chr5:10229023(-) A-I      intronic chr5:10228860(-) A-I      intronic chr5:10234195(-) A-I      intronic chr5:10247716(-) A-I      intronic chr5:10228156(-) A-I      intronic chr5:10228937(-) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-4677-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	ATPSCKMT	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-4677-3p
Interactor2: ATPSCKMT

Evidence Support:

Weak-Evidence	Small RNA sequencing
Prediction-Evidence	miRNet
Support Database	ViRBase

References:

PMID	33045840	Target region	None
Source	ViRBase	Interactor1 expression	Downregulation
Tissue or cell line	PBMC cells	Interactor2 expression	Upregulation
Description	FIG. 2.(A) Downregulated miRNAs with their predicted upregulated gene targets.