Basic Information:

  VIRBase ID:  

HHID00096421

  Virus:  

Human immunodeficiency virus (HIV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-150-3p:  MIMAT0004610          WDR64:  NM_001367482     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-150-3p	WDR64
miRBase Accession/Entrez ID	MIMAT0004610	128025
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-150-3p	rs1222701309 chr19:49500798    T/C rs1268655804 chr19:49500801    C/T rs1479556921 chr19:49500803    C/A rs900688289 chr19:49500802    C/T rs1184577625 chr19:49500811    T/C rs1270941119 chr19:49500816    C/T rs1413039185 chr19:49500817    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	WDR64	chr1:241960056(+) A-I      intronic chr1:241960078(+) A-I      intronic chr1:241916140(+) A-I      intronic chr1:241916010(+) A-I      intronic chr1:241915991(+) A-I      intronic chr1:241915987(+) A-I      intronic chr1:241915970(+) A-I      intronic chr1:241948003(+) A-I      intronic chr1:241936871(+) A-I      intronic chr1:241872077(+) A-I      intronic chr1:241837809(+) A-I      intronic chr1:241963850(+) A-I      intronic chr1:241963869(+) A-I      intronic chr1:241840068(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-150-3p	Exosome Saliva     19627513 Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
	WDR64	Cytosol K562 cells     - Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-150-3p	Ginsenoside Rh2 119307 Drug interaction    RC00006970 Androstanolone 10635 Drug interaction    RC00006969

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-150-3p	Imatinib 5291       25349971

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-150-3p
Interactor2: WDR64

Evidence Support:

Weak-Evidence	Small RNA sequencing
Prediction-Evidence	miRNet
Support Database	ViRBase

References:

PMID	33045840	Target region	None
Source	ViRBase	Interactor1 expression	Downregulation
Tissue or cell line	PBMC cells	Interactor2 expression	Upregulation
Description	FIG. 2.(A) Downregulated miRNAs with their predicted upregulated gene targets.