Detail Information

Basic Information:


  VIRBase ID:  

HHID00096417

  Virus:  

Human immunodeficiency virus (HIV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-150-3p:           TK2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-150-3p TK2
miRBase
Accession/Entrez ID		 MIMAT0004610 7084
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - MTDPS2//MTTK//PEOB3//SCA31

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-150-3p
rs1222701309 chr19:49500798    T/C
rs1268655804 chr19:49500801    C/T
rs1479556921 chr19:49500803    C/A
rs900688289 chr19:49500802    C/T
rs1184577625 chr19:49500811    T/C
rs1270941119 chr19:49500816    C/T
rs1413039185 chr19:49500817    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TK2
chr16:66574148(-) A-I      intronic
chr16:66574173(-) A-I      intronic
chr16:66574174(-) A-I      intronic
chr16:66574178(-) A-I      intronic
chr16:66580832(-) A-I      intronic
chr16:66580857(-) A-I      intronic
chr16:66572066(-) A-I      intronic
chr16:66572064(-) A-I      intronic
chr16:66580826(-) A-I      intronic
chr16:66580833(-) A-I      intronic
chr16:66580831(-) A-I      intronic
chr16:66580823(-) A-I      intronic
chr16:66580819(-) A-I      intronic
chr16:66580803(-) A-I      intronic
chr16:66580744(-) A-I      intronic
chr16:66580086(-) A-I      intronic
chr16:66580025(-) A-I      intronic
chr16:66580021(-) A-I      intronic
chr16:66579547(-) A-I      intronic
chr16:66579484(-) A-I      intronic
chr16:66578921(-) A-I      intronic
chr16:66578907(-) A-I      intronic
chr16:66567436(-) A-I      intronic
chr16:66567434(-) A-I      intronic
chr16:66567110(-) A-I      intronic
chr16:66553003(-) A-I      intronic
chr16:66552976(-) A-I      intronic
chr16:66574214(-) A-I      intronic
chr16:66580799(-) A-I      intronic
chr16:66560560(-) A-I      intronic
chr16:66580883(-) A-I      intronic
chr16:66580097(-) A-I      intronic
chr16:66578914(-) A-I      intronic
chr16:66558274(-) A-I      intronic
chr16:66567058(-) A-I      intronic
chr16:66575467(-) A-I      intronic
chr16:66580829(-) A-I      intronic
chr16:66580687(-) A-I      intronic
chr16:66579958(-) A-I      intronic
chr16:66580859(-) A-I      intronic
chr16:66574335(-) A-I      intronic
chr16:66580001(-) A-I      intronic
chr16:66580834(-) A-I      intronic
chr16:66558530(-) A-I      intronic
chr16:66556766(-) A-I      intronic
chr16:66580793(-) A-I      intronic
chr16:66580928(-) A-I      intronic
chr16:66579967(-) A-I      intronic
chr16:66560508(-) A-I      intronic
chr16:66580051(-) A-I      intronic
chr16:66580835(-) A-I      intronic
chr16:66580080(-) A-I      intronic
chr16:66580852(-) A-I      intronic
chr16:66567153(-) A-I      intronic
chr16:66580931(-) A-I      intronic
chr16:66579976(-) A-I      intronic
chr16:66580083(-) A-I      intronic
chr16:66578913(-) A-I      intronic
chr16:66567069(-) A-I      intronic
chr16:66553477(-) A-I      intronic
chr16:66580738(-) A-I      intronic
chr16:66579985(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TK2
chr16:66543502-66543503(-) m6A 3'UTR//intron       24284625
chr16:66543519-66543520(-) m6A 3'UTR//intron       24284625
chr16:66543695-66543696(-) m6A 3'UTR//intron       24284625//27773536
chr16:66543704-66543705(-) m6A 3'UTR//intron       24284625//27773536
chr16:66543801-66543802(-) m6A 3'UTR//intron       24284625//27773536
chr16:66544082-66544083(-) m6A 3'UTR//intron       27773535
chr16:66544197-66544198(-) m6A 3'UTR//intron       24981863
chr16:66544254-66544255(-) m6A 3'UTR//intron       24981863
chr16:66544269-66544270(-) m6A 3'UTR//intron       24981863
chr16:66544555-66544556(-) m6A 3'UTR//intron       24209618//25456834//24981863//27773535//22608085
chr16:66544589-66544590(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22608085
chr16:66544600-66544601(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22608085
chr16:66544722-66544723(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr16:66544763-66544764(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr16:66544879-66544880(-) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22608085
chr16:66545053-66545054(-) m6A 3'UTR//intron       24284625//24209618//24981863//22608085
chr16:66545120-66545121(-) m6A 3'UTR//exon//intron       24284625//24209618//24981863//22608085
chr16:66545217-66545218(-) m6A 3'UTR//intron       24284625//24209618//24981863//22608085
chr16:66545234-66545235(-) m6A 3'UTR//intron       24284625//24981863
chr16:66545399-66545400(-) m6A 3'UTR//intron       24284625//24981863
chr16:66545678-66545679(-) m6A 3'UTR//exon//intron       24284625//24981863
chr16:66545893-66545894(-) Gm 3'UTR//CDS//exon//intron       -
chr16:66583598-66583599(-) m6A 5'UTR//intron       27773536
chr16:66583669-66583670(-) m6A 5'UTR//intron       27773536
chr16:66583994-66583995(-) m6A 5'UTR//CDS//intron       24981863
chr16:66584030-66584031(-) m6A 5'UTR//CDS//intron       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-150-3p
Exosome Saliva     19627513
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
TK2
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-150-3p
Ginsenoside Rh2 119307 Drug interaction    RC00006970
Androstanolone 10635 Drug interaction    RC00006969
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-150-3p
Imatinib 5291       25349971

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-150-3p
Interactor2: TK2

Evidence Support:


Weak-Evidence Small RNA sequencing
Prediction-Evidence miRNet
Support Database ViRBase

References:


PMID 33045840 Target region None
Source ViRBase Interactor1 expression Downregulation
Tissue or cell line PBMC cells Interactor2 expression Upregulation
Description FIG. 2.(A) Downregulated miRNAs with their predicted upregulated gene targets.

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