Basic Information:

  VIRBase ID:  

HHID00096416

  Virus:  

Human immunodeficiency virus (HIV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-150-3p:  MIMAT0004610          MPZ:  NM_000530     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-150-3p	MPZ
miRBase Accession/Entrez ID	MIMAT0004610	4359
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CHM//CHN2//CMT1//CMT1B//CMT2I//CMT2J//CMT4E//CMTDI3//CMTDID//DSS//HMSNIB//MPP//P0

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-150-3p	rs1222701309 chr19:49500798    T/C rs1268655804 chr19:49500801    C/T rs1479556921 chr19:49500803    C/A rs900688289 chr19:49500802    C/T rs1184577625 chr19:49500811    T/C rs1270941119 chr19:49500816    C/T rs1413039185 chr19:49500817    A/G

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MPZ	chr1:161274930-161274931(-) m6A 3'UTR       27773535 chr1:161275198-161275199(-) m6A 3'UTR//exon//intron       27773535 chr1:161275480-161275481(-) m6A 3'UTR//exon       25456834 chr1:161275486-161275487(-) m6A 3'UTR//exon       25456834 chr1:161275501-161275502(-) m6A 3'UTR//exon       25456834 chr1:161275526-161275527(-) m6A 3'UTR//exon       25456834 chr1:161275741-161275742(-) m6A CDS//exon       - chr1:161275816-161275817(-) m6A exon//intron       - chr1:161275857-161275858(-) m6A exon//intron       - chr1:161275874-161275875(-) m6A exon//intron       - chr1:161275887-161275888(-) m6A exon//intron       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-150-3p	Exosome Saliva     19627513 Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
	MPZ	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-150-3p	Ginsenoside Rh2 119307 Drug interaction    RC00006970 Androstanolone 10635 Drug interaction    RC00006969

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-150-3p	Imatinib 5291       25349971

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-150-3p
Interactor2: MPZ

Evidence Support:

Weak-Evidence	Small RNA sequencing
Prediction-Evidence	miRNet
Support Database	ViRBase

References:

PMID	33045840	Target region	None
Source	ViRBase	Interactor1 expression	Downregulation
Tissue or cell line	PBMC cells	Interactor2 expression	Upregulation
Description	FIG. 2.(A) Downregulated miRNAs with their predicted upregulated gene targets.