Basic Information:

  VIRBase ID:  

HHID00096410

  Virus:  

Human immunodeficiency virus (HIV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-148a-5p:  MIMAT0004549          ZNF788P:  NR_171043     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-148a-5p	ZNF788P
miRBase Accession/Entrez ID	MIMAT0004549	388507
Organism	Homo sapiens	Homo sapiens
Category	miRNA	pseudo
Alias	-	ZNF788

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-148a-5p	rs1169404442 chr7:25949960    A/G rs1305387183 chr7:25949963    C/T rs1340640170 chr7:25949981    T/C rs1382103906 chr7:25949968    T/C rs1392050107 chr7:25949964    G/A rs752022883 chr7:25949961    G/A rs758401446 chr7:25949962    TC/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZNF788P	chr19:12217557(+) A-I      intronic chr19:12217538(+) A-I      intronic chr19:12217560(+) A-I      intronic chr19:12205232(+) A-I      intronic chr19:12217567(+) A-I      intronic chr19:12219229(+) A-I      intronic chr19:12205354(+) A-I      intronic chr19:12205888(+) A-I      intronic chr19:12205920(+) A-I      intronic chr19:12217539(+) A-I      intronic chr19:12217602(+) A-I      intronic chr19:12217466(+) A-I      intronic chr19:12217610(+) A-I      intronic chr19:12218245(+) A-I      intronic chr19:12218317(+) A-I      intronic chr19:12218353(+) A-I      intronic chr19:12218362(+) A-I      intronic chr19:12218441(+) A-I      intronic chr19:12219096(+) A-I      intronic chr19:12219158(+) A-I      intronic chr19:12219212(+) A-I      intronic chr19:12204488(+) A-I      intronic chr19:12203713(+) A-I      intronic chr19:12203723(+) A-I      intronic chr19:12205916(+) A-I      intronic chr19:12218236(+) A-I      intronic chr19:12205037(+) A-I      intronic chr19:12203695(+) A-I      intronic chr19:12203772(+) A-I      intronic chr19:12204879(+) A-I      intronic chr19:12204367(+) A-I      intronic chr19:12219151(+) A-I      intronic chr19:12217637(+) A-I      intronic chr19:12205031(+) A-I      intronic chr19:12218231(+) A-I      intronic chr19:12217545(+) A-I      intronic chr19:12205947(+) A-I      intronic chr19:12217626(+) A-I      intronic chr19:12203759(+) A-I      intronic chr19:12206115(+) A-I      intronic chr19:12219203(+) A-I      intronic chr19:12204442(+) A-I      intronic chr19:12218760(+) A-I      intronic chr19:12217680(+) A-I      intronic chr19:12217652(+) A-I      intronic chr19:12218290(+) A-I      intronic chr19:12219086(+) A-I      intronic chr19:12218763(+) A-I      intronic chr19:12203750(+) A-I      intronic chr19:12204875(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-148a-5p	Exosome Peripheral blood     31746410 Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Breast milk     22211110 Exosome Plasma     23663360 Exosome B lymphoblastoid cells|Breast milk|Chronic lymphocytic leukemia cells|Seminal fluid     - Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	ZNF788P	Chromatin K562 cells     - Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-148a-5p
Interactor2: ZNF788P

Evidence Support:

Weak-Evidence	Small RNA sequencing
Prediction-Evidence	miRNet
Support Database	ViRBase

References:

PMID	33045840	Target region	None
Source	ViRBase	Interactor1 expression	Downregulation
Tissue or cell line	PBMC cells	Interactor2 expression	Upregulation
Description	FIG. 2.(A) Downregulated miRNAs with their predicted upregulated gene targets.