Detail Information

Basic Information:


  VIRBase ID:  

HHID00096392

  Virus:  

Human immunodeficiency virus (HIV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-2-3p:           RHOC:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-2-3p RHOC
miRBase
Accession/Entrez ID		 MIMAT0004518 389
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ARH9//ARHC//H9//RHOH9

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-2-3p
rs1341798864 chr3:160404818    A/C
rs373202341 chr3:160404806    C/T
rs768780684 chr3:160404809    T/C
rs768780684 chr3:160404809    T/G
rs746992239 chr3:160404798    C/CA
rs775368833 chr3:160404800    A/G
rs775368833 chr3:160404800    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RHOC
chr1:113249052(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED RHOC
chr1:113249052(-) A-I intron -    21960545

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RHOC
chr1:113244035-113244036(-) m6A 3'UTR//exon       24284625//26404942//27773535
chr1:113244192-113244193(-) m6A 3'UTR//CDS//exon       24284625//27773535//27371828//27773536
chr1:113244256-113244257(-) m6A 3'UTR//CDS//exon       24284625//27773535//27371828//27773536
chr1:113244297-113244298(-) m6A 3'UTR//CDS//exon       24284625//24981863//26404942//27773535//27371828//27773536//22575960
chr1:113244306-113244307(-) m6A 3'UTR//CDS//exon       24284625//24981863//26404942//27773535//27371828//27773536//22575960
chr1:113245233-113245234(-) m6A 3'UTR//CDS//exon       24284625//24981863//26404942//27773535//27371828//27773536//22575960
chr1:113245294-113245295(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//27371828//27773536//22575960
chr1:113245311-113245312(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//27371828//27773536//22575960
chr1:113245400-113245401(-) m6A exon//intron       27773535//27371828//27773536
chr1:113245425-113245426(-) m6A exon//intron       27773535//27371828//27773536
chr1:113245597-113245598(-) m6A exon//intron       27773535
chr1:113245670-113245671(-) m6A 3'UTR//CDS//exon       24284625//27773535//27371828//27773536//22575960
chr1:113245703-113245704(-) m6A 3'UTR//CDS//exon       24284625//27773535//27371828//27773536//22575960
chr1:113245721-113245722(-) m6A 3'UTR//CDS//exon       24284625//27773535//27371828//27773536//22575960
chr1:113246147-113246148(-) m6A exon//intron       27773535
chr1:113246287-113246288(-) m6A CDS//exon       24284625//26404942//27773535//27371828//27773536//22575960
chr1:113246299-113246300(-) m6A CDS//exon       24284625//26404942//27773535//27371828//27773536//22575960
chr1:113246366-113246367(-) m6A CDS//exon       24284625//25456834//24981863//27371828//27773536//22575960
chr1:113246906-113246907(-) m6A 5'UTR//intron       24284625//25456834//24981863//27371828//27773536
chr1:113246925-113246926(-) m6A 5'UTR//intron       24284625//25456834//24981863//27371828//27773536
chr1:113247737-113247738(-) m6A 5'UTR//CDS//exon//intron       24284625//25456834//24981863//27371828//27773536
chr1:113247817-113247818(-) m6A 5'UTR//intron       24981863//27773536
chr1:113247862-113247863(-) m6A 5'UTR//intron       24981863//27773536
chr1:113249410-113249411(-) m6A 5'UTR//intron       27773536
chr1:113249483-113249484(-) m6A 5'UTR//intron       27773536
chr1:113249524-113249525(-) m6A 5'UTR//intron       27773536
chr1:113249573-113249574(-) m6A 5'UTR//intron       27773536
chr1:113249657-113249658(-) m6A 5'UTR//intron       24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-2-3p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Blood|Chronic lymphocytic leukemia cells|Tongue tissue     -
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
RHOC
Chromatin K562 cells     -
Cytoplasm Esophageal squamous cells     25624724
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-2-3p
Interactor2: RHOC

Evidence Support:


Weak-Evidence Small RNA sequencing
Prediction-Evidence miRNet
Support Database ViRBase

References:


PMID 33045840 Target region None
Source ViRBase Interactor1 expression Downregulation
Tissue or cell line PBMC cells Interactor2 expression Upregulation
Description FIG. 2.(A) Downregulated miRNAs with their predicted upregulated gene targets.

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